Bioadhesives Market Report

Global Bioadhesives Market Size

The global bioadhesives market size was valued at USD 9.68 billion in 2024 and is expected to reach USD 20.53 billion by 2033 from USD 10.52 billion in 2025. The market is projected to grow at a CAGR of 8.71% during the forecast period.

Bioadhesives refer to naturally derived or bio-based adhesives that form strong bonds with biological surfaces such as skin, mucous membranes, and tissues. These materials are widely used in medical, pharmaceutical, dental, and cosmetic applications due to their biocompatibility, biodegradability, and reduced toxicity compared to synthetic alternatives. Unlike conventional adhesives, which often contain harmful solvents and non-degradable components, bioadhesives are formulated using natural polymers like proteins, polysaccharides, and lipids, making them suitable for use in sensitive environments.

The growing emphasis on sustainable and eco-friendly product development has significantly increased interest in bioadhesives across industries. According to the United Nations Environment Programme, global concerns over plastic waste and chemical pollution have prompted manufacturers to seek renewable and environmentally safe alternatives. In addition, the healthcare sector’s demand for advanced wound care solutions, drug delivery systems, and surgical sealants has further accelerated the adoption of bioadhesive technologies.

As per the World Health Organization, the need for infection control and minimally invasive medical procedures has led to increased research into biocompatible materials, including bioadhesives. The European Commission has also introduced regulatory frameworks encouraging the development of green chemistry-based products, reinforcing the shift away from petroleum-derived adhesives.

So, with rising environmental awareness, stringent health regulations, and ongoing technological advancements, the bioadhesives market is witnessing robust growth, driven by both industrial innovation and evolving consumer expectations toward sustainability.

MARKET DRIVERS

Rising Demand for Biocompatible Medical Solutions

One of the primary drivers of the bioadhesives market is the increasing demand for biocompatible materials in the medical and healthcare sectors. As hospitals and clinics prioritize patient safety and reduce reliance on invasive procedures, bioadhesives have become essential in applications such as wound closure, tissue repair, and controlled drug delivery.

According to the World Health Organization, the global push for safer surgical outcomes has led to a surge in the adoption of bio-based surgical glues and hemostatic agents that minimize infection risks and improve healing times.

Moreover, traditional sutures and staples can cause inflammation and scarring, prompting a shift toward less intrusive alternatives. For instance, fibrin-based bioadhesives are increasingly used in cardiovascular and neurological surgeries due to their ability to bond tissues without causing adverse immune reactions.

Additionally, the rise in chronic diseases such as diabetes and cardiovascular disorders has expanded the need for advanced wound management products. As governments and healthcare institutions invest in better post-operative care, the demand for bioadhesives continues to grow, supported by continuous R&D efforts aimed at enhancing their mechanical strength and antimicrobial properties.

Increasing Regulatory Support for Sustainable and Green Manufacturing Practices

Another significant driver of the bioadhesives market is the growing regulatory support for sustainable and environmentally friendly manufacturing practices. Governments worldwide are implementing policies to reduce industrial carbon footprints and promote the use of biodegradable materials.

According to the European Commission, the EU’s Green Deal initiative includes incentives for companies that replace petroleum-based chemicals with renewable alternatives, directly benefiting the bioadhesives industry.

In the U.S., the Environmental Protection Agency has introduced guidelines under its Safer Choice Program, encouraging manufacturers to adopt greener formulations. As per the Organisation for Economic Co-operation and Development, these regulatory shifts have led to increased investments in bio-based material research, particularly in the packaging, textile, and biomedical sectors.

Furthermore, consumer awareness regarding environmental issues has pressured companies to reevaluate their supply chains and opt for sustainable raw materials. Industry leaders such as Henkel and BASF have launched eco-conscious adhesive lines derived from plant-based sources, aligning with corporate sustainability goals.

Universities and research institutions are also contributing by developing novel extraction techniques from agricultural waste and marine organisms.

MARKET RESTRAINTS

High Production Costs and Limited Shelf Life of Natural Ingredients

A major restraint affecting the bioadhesives market is the high production cost associated with sourcing and processing natural ingredients. Unlike synthetic adhesives, which rely on inexpensive petroleum-based feedstocks, bioadhesives require organic raw materials such as chitosan, gelatin, starch, and alginate, which are often more expensive to extract and refine.

Besides, many bioadhesives suffer from shorter shelf life due to microbial degradation and sensitivity to environmental conditions such as humidity and temperature. As per the American Chemical Society, some protein-based adhesives exhibit stability issues beyond six months, requiring additional preservatives or specialized packaging, which further increases costs.

These limitations hinder the economic viability of bioadhesives for mass production, particularly in industries where cost efficiency is crucial.

Technical Limitations in Adhesion Strength and Durability Compared to Synthetic Alternatives

Another key constraint in the bioadhesives market is the relatively lower adhesion strength and durability when compared to synthetic adhesives. Many bioadhesives struggle to maintain structural integrity under extreme mechanical stress, moisture exposure, or fluctuating temperatures.

As per the Journal of Biomedical Materials Research, this limitation restricts the use of bioadhesives in critical areas such as orthopedic surgery and deep tissue repair.

While researchers are exploring cross-linking agents and hybrid formulations to enhance performance, achieving parity with synthetic adhesives remains a challenge.

MARKET OPPORTUNITIES

Growing Application in Advanced Wound Care and Tissue Engineering

An emerging opportunity within the bioadhesives market lies in their expanding role in advanced wound care and tissue engineering. As the global burden of chronic wounds—such as diabetic ulcers, pressure sores, and surgical incisions—continues to rise, there is an increasing need for innovative solutions that accelerate healing while minimizing infection risks. According to the World Health Organization, millions of patients suffer from non-healing wounds annually, necessitating the development of bioactive and biocompatible wound dressings.

Bioadhesives play a crucial role in this domain by offering secure adherence to delicate tissues, enabling controlled drug release, and promoting cellular regeneration. As per the National Institutes of Health, recent advancements in hydrogel-based bioadhesives have demonstrated superior performance in sealing soft tissues and reducing scarring.

Besides, their integration into 3D-printed scaffolds for regenerative medicine is opening new avenues for personalized treatment approaches.

Expansion into Eco-Friendly Packaging and Textile Industries

Another significant opportunity for the bioadhesives market is the growing demand for sustainable adhesives in the packaging and textile industries. As environmental regulations tighten and consumer preferences shift toward recyclable and biodegradable products, manufacturers are actively seeking alternatives to petroleum-based glues used in labels, laminates, and fabric bonding. According to the Ellen MacArthur Foundation, the circular economy movement is driving brands to eliminate non-renewable materials from their supply chains, creating a favorable environment for bioadhesive adoption.

In the packaging sector, companies are integrating starch- and cellulose-based adhesives for corrugated board, flexible films, and food-safe containers. Similarly, in textiles, bioadhesives are being explored for garment lamination, non-woven fabrics, and smart apparel applications. As per the International Trade Centre, sustainable fashion initiatives have spurred interest in biodegradable binding agents that align with ethical production standards.

MARKET CHALLENGES

Lack of Standardization and Scalable Manufacturing Processes

One of the foremost challenges facing the bioadhesives market is the lack of standardized formulations and scalable manufacturing processes. Unlike synthetic adhesives, which follow well-established production protocols, bioadhesives often involve complex formulations derived from diverse natural sources, leading to inconsistencies in performance and quality. According to the Organisation for Economic Co-operation and Development, the absence of uniform testing methodologies and certification criteria hampers commercialization efforts and slows down regulatory approvals.

Moreover, scaling up production while maintaining batch-to-batch consistency remains a technical hurdle. As per the Journal of Industrial Microbiology and Biotechnology, variations in raw material composition—especially when sourced from agricultural or marine origins—can impact adhesive properties such as viscosity, curing time, and bonding strength. This variability complicates large-scale deployment and discourages widespread adoption in industries reliant on precision and reliability.

Limited Awareness and Adoption in Developing Markets

Another pressing challenge in the bioadhesives market is the limited awareness and slow adoption rates in developing economies. Despite growing global momentum toward sustainability, many manufacturers in emerging regions continue to rely on conventional adhesives due to familiarity, cost considerations, and inadequate access to updated information on bio-based alternatives.

In addition, the absence of government incentives and weak enforcement of environmental regulations contribute to low uptake. As per the International Renewable Energy Agency, only a handful of developing nations have implemented clear policy frameworks promoting bio-based industrial inputs, leaving businesses with little motivation to switch from cheaper synthetic options.

Educational gaps among industry professionals and limited availability of trained personnel further delay technology transfer and implementation.

REPORT COVERAGE

SEGMENTAL ANALYSIS

By Type Insights

The plant-based bioadhesives segment dominated the global bioadhesives market, accounting for 68.3% of total market revenue in 2024. This dominance is primarily attributed to the increasing demand for sustainable and renewable materials across industries such as packaging, paper, textiles, and personal care.

One key driver behind this segment’s leadership is the growing consumer preference for eco-friendly and biodegradable products, especially in light of rising environmental awareness and regulatory pressures on plastic reduction.

Another major factor is the availability and scalability of raw materials such as starch, cellulose, lignin, and natural gums , which are widely used in adhesive formulations. The Food and Agriculture Organization reports that global starch production exceeded 75 million metric tons in 2023, providing a steady supply base for adhesive manufacturers.

Besides, plant-based adhesives are often more cost-effective and easier to modify chemically for improved performance, making them attractive for industrial applications.

The animal-based bioadhesives segment is projected to grow at the fastest rate, registering a CAGR of 7.9%. While currently smaller than the plant-based segment, it is gaining momentum due to its superior biocompatibility and mechanical strength in medical and pharmaceutical applications.

A primary driver of this growth is the increasing use of animal-derived proteins such as gelatin, fibrin, collagen, and chitosan in surgical adhesives and wound healing products. According to the National Institutes of Health, animal-based bioadhesives exhibit excellent hemostatic properties and tissue integration, making them ideal for internal surgical bonding and controlled drug delivery systems.

In addition, advancements in recombinant protein engineering and marine-derived adhesives have expanded the functional capabilities of animal-based bioadhesives. With rising R&D funding and growing healthcare investments, the animal-based bioadhesives segment is poised for rapid expansion, particularly in advanced medical applications where performance and biocompatibility are critical.

By Application Insights

The paper and packaging application segment held the largest share of the bioadhesives market, contributing 34.1% of total industry revenue in 2024. This widespread usage stems from the industry's reliance on biodegradable adhesives for corrugated boxes, labels, laminates, and flexible packaging materials.

One of the key reasons for this segment’s dominance is the global shift toward sustainable packaging solutions driven by consumer demand and government regulations.

Additionally, bioadhesives offer enhanced compatibility with food-grade packaging , ensuring safety and reducing chemical migration risks. According to the International Trade Centre, starch-based and protein-derived adhesives are increasingly used in food and beverage packaging due to their non-toxic nature and ease of processing.

Moreover, the expansion of e-commerce and logistics sectors has led to higher demand for corrugated cardboard and shipping materials, further driving adhesive consumption.

The medical applications segment is anticipated to grow at the highest compound annual growth rate (CAGR) of 8.6% between 2023 and 2030 , as per Allied Market Research. This rapid expansion reflects the increasing adoption of bioadhesives in wound care, surgical bonding, tissue engineering, and drug delivery systems.

A primary driver of this growth is the rising prevalence of chronic wounds, surgical procedures, and diabetic ulcers, necessitating advanced wound management solutions. According to the World Health Organization, millions of patients worldwide suffer from non-healing wounds annually, prompting healthcare providers to seek effective and biocompatible treatment options.

Furthermore, technological advancements in hydrogel-based and mussel-inspired bioadhesives have enabled stronger bonding in wet environments , making them suitable for internal surgeries.

In addition, regulatory approvals and product launches by major players have accelerated market penetration . Companies such as Becton Dickinson and Ethicon have introduced FDA-approved surgical glues derived from natural sources, enhancing adoption in hospitals and ambulatory care centers.

REGIONAL ANALYSIS

North America

North America accounted for the largest share of the global bioadhesives market, capturing 32.5% of total revenue in 2024. The United States serves as the epicenter of innovation and early adoption, driven by stringent environmental regulations, robust R&D infrastructure, and a strong presence of major adhesive manufacturers.

A key factor behind North America’s leadership is the stringent regulatory framework promoting the use of bio-based materials , particularly in packaging and healthcare. According to the U.S. Environmental Protection Agency, federal initiatives such as the Safer Choice Program have encouraged companies to replace petroleum-based adhesives with greener alternatives, accelerating market growth.

In addition, the region benefits from high consumer awareness and brand-driven sustainability commitments, particularly among Fortune 500 companies in the consumer goods and pharmaceutical sectors. With strong government backing, extensive academic research, and a thriving startup ecosystem focused on green chemistry, North America continues to lead the transition toward sustainable adhesive solutions globally.

Europe

Europe is another key player in the market. The region has emerged as a frontrunner in adopting bio-based materials due to proactive environmental policies and growing corporate responsibility initiatives.

One of the main drivers is the European Union’s Green Deal strategy, which mandates a transition toward circular economy principles and reduced carbon emissions. According to the European Commission, member states have implemented tax incentives and subsidies for companies utilizing renewable raw materials, directly benefiting the bioadhesives industry.

Apart from these, Germany, France, and the Netherlands serve as innovation hubs , with universities and research institutions developing next-generation bioadhesive formulations.

Consumer demand for sustainable products is also influencing purchasing behavior, prompting major retailers and packaging firms to adopt bioadhesives in their operations.

Asia Pacific

Asia Pacific represents one of the fastest-growing regions in the bioadhesives market. Countries like China, India, Japan, and South Korea are witnessing rapid industrialization and increasing demand for sustainable materials across packaging, woodworking, and textile sectors.

China leads the region in terms of production and consumption. India has also seen significant growth, with according to the Indian Chemical Council, an increase in bioadhesive imports and local production between 2021 and 2023 , driven by expanding e-commerce and food packaging industries.

Moreover, Japanese and Korean companies are investing heavily in bio-based R&D , particularly for medical and electronic applications.

Latin America

Latin America contributes a notable share of the global bioadhesives market. Brazil plays a pivotal role due to its vast availability of sugarcane, cassava, and soybean derivatives, which serve as feedstocks for bio-based adhesives. Also, Mexico has also witnessed rising adoption, particularly in the automotive and construction sectors, where bioadhesives are used for interior components and insulation materials. With supportive trade agreements and increasing foreign direct investment, Latin America is becoming an increasingly important market for bioadhesives, offering long-term growth opportunities.

Middle East and Africa

The Middle East and Africa collectively represent a small but steadily growing region. While initial adoption rates have been slow, recent developments indicate increasing interest in sustainable material alternatives.

In the Gulf Cooperation Council (GCC) countries, governments are promoting green building standards and eco-friendly manufacturing practices.

South Africa leads the African sub-region in terms of industrial application, particularly in the packaging and textile industries. As digital transformation and environmental awareness continue to spread, the Middle East and Africa present untapped opportunities for bioadhesive market participants willing to adapt to regional needs and resource constraints.

KEY MARKET PLAYERS AND COMPETITIVE LANDSCAPE

Henkel AG (Germany), DuPont de Nemours, Inc., (US), Ashland Global Holdings Inc. (US), Arkema S.A., DaniMer Scientific LLC, The Compound Company (Netherlands), Cryolife Inc., (US), Jowat SE (Germany), Kollodis BioSciences, Inc., (US), Tate & Lyle PLC (UK), L.D. Davis Industries, Inc., and Ingredion Incorporated (US) are the key players in the global bioadhesives market.

The competition in the bioadhesives market is intensifying as both established chemical giants and emerging biotech firms vie for dominance in a rapidly evolving landscape. While traditional adhesive manufacturers are transitioning toward sustainable formulations to align with global environmental mandates, new entrants specializing in bio-based materials are challenging the status quo with innovative product offerings. Market leaders leverage their existing infrastructure, R&D budgets, and global distribution networks to maintain competitive advantage, but smaller niche players are gaining traction by offering highly specialized, eco-friendly alternatives tailored to specific industry needs.

Strategic differentiation is increasingly centered around performance enhancement, cost-efficiency, and customization, with companies investing heavily in biomaterials science and green chemistry. As sustainability becomes a core purchasing criterion across industries, the battle for market share is shifting from price and volume to innovation and environmental impact. With regulatory pressures mounting and consumer awareness rising, the bioadhesives sector is witnessing a dynamic transformation where adaptability and forward-thinking positioning determine long-term success.

TOP PLAYERS IN THE BIOADHESIVES MARKET

Henkel AG & Co. KGaA

Henkel is a global leader in adhesives, sealants, and functional coatings, with a strong presence in the bioadhesives sector. The company has been instrumental in developing sustainable adhesive solutions for packaging, consumer goods, and industrial applications. Henkel’s Loctite brand includes several bio-based formulations that support corporate sustainability goals while maintaining high-performance standards across diverse industries.

Ashland Global Holdings Inc.

Ashland is a major player in specialty chemicals, offering advanced bioadhesive solutions primarily for pharmaceutical, personal care, and food packaging sectors. The company emphasizes innovation through its research-driven product development, focusing on natural polymers and plant-derived ingredients to meet evolving regulatory and environmental standards across global markets.

BASF SE

BASF has integrated bio-based materials into its extensive adhesive portfolio, contributing significantly to the shift away from petroleum-derived alternatives. The company focuses on scalable, renewable feedstocks and collaborates with academic and industry partners to develop next-generation bioadhesives tailored for packaging, textiles, and medical applications, reinforcing its leadership in green chemistry.

TOP STRATEGIES USED BY KEY MARKET PLAYERS

Investing in R&D for Advanced Bio-Based Formulations

Leading companies are prioritizing research and development to create innovative bioadhesive products with improved performance characteristics such as enhanced bonding strength, faster curing times, and greater resistance to moisture and temperature variations.

Forming Strategic Partnerships and Collaborations

To accelerate market penetration and technological advancement, key players are forming alliances with universities, biotech firms, and raw material suppliers to co-develop novel adhesive technologies and ensure a stable supply chain of sustainable inputs.

Expanding Production Capacities and Regional Footprints

Major manufacturers are scaling up production capabilities and entering emerging markets to meet growing demand. This includes setting up new manufacturing units, acquiring regional players, and tailoring product offerings to local industry requirements.

RECENT HAPPENINGS IN THE MARKET

• In February 2024, Henkel launched a new line of plant-based adhesives under its Loctite brand, specifically designed for flexible packaging applications, aiming to support global brands in achieving recyclable and compostable packaging targets.
• In March 2024, BASF entered into a strategic partnership with a U.S.-based biotechnology firm to co-develop protein-based adhesives for use in wound care and surgical applications, enhancing its portfolio in the medical segment.
• In May 2024, Ashland announced the expansion of its bioadhesive production facility in Europe to meet rising demand from the personal care and pharmaceutical sectors, reinforcing its position as a leading supplier of natural excipients and binding agents.
• In June 2024, Solvay introduced a bio-based hot melt adhesive derived from lignin, targeting the woodworking and furniture industries, positioning itself as a key innovator in sustainable industrial bonding solutions.
• In July 2024, AkzoNobel invested in a startup specializing in mussel-inspired bioadhesives, aiming to commercialize high-strength, water-resistant adhesives for marine and biomedical applications, marking a significant step toward diversifying its sustainable product lineup.

MARKET SEGMENTATION

This research report on the global Bioadhesives market has been segmented and sub-segmented based on type, application, and region.

By Type

• Plant-Based
• Animal Based

By Application

• Paper and Packaging
• Construction
• Woodworking
• Personal Care
• Medical
• Others

By Region

• North America
• Europe
• Asia-Pacific
• Latin America
• Middle East and Africa