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Global Gene Expression Analysis Market Size, Share, Trends, COVID-19 Impact & Growth Analysis Report – Segmented By Technology, Consumables, Services, Application & Region - Industry Forecast (2022 to 2027)

Published: January, 2022
ID: 3390
Pages: 175
Formats: report pdf report excel report power bi report ppt

Gene Expression Analysis Market Size (2022 to 2027)

The global gene expression analysis market size was valued at USD 4.95 Billion in 2022. It is further projected to be growing at a CAGR of 9.5% and be worth USD 7.79 Billion by 2027.

Gene expression analysis studies the gene transcription process for functional gene product synthesis, called protein products or functional RNA species. This study provides information on gene regulation of normal cellular processes, such as differentiation, and abnormal or pathological processes. Gene expression analysis helps to produce a gene product by extracting data from a gene. This process will show its wide range of benefits in applications such as pharmacogenomics, diagnostics, biomarkers, and toxicology. Gene expression processes DNA pairs into a functional gene product such as proteins or RNA. In this analysis, the first step is translating DNA into RNA, then translating into proteins.

Some of the key findings of the report:

  • Based on technology, the DNA microarray and NGS segments had the leading share of the gene expression analysis market.
  • Based on the consumables, the DNA chips segment accounted for the major share of the market in 2021.
  • The North American gene expression analysis market is anticipated to be worth USD 6.06 billion by 2027.
  • Europe's gene expression analysis market was valued at USD 1.37 billion in 2021.
  • The Asia-Pacific gene expression analysis market is estimated to grow at a CAGR of 11.49% from 2022 to 2027.
  • The gene expression analysis market in Latin America and MEA are projected to grow at a CAGR of 10.44% and 7.76%, respectively, during the forecast period.


Increased research activities on DNA studies, YOY rise in the number of cancer patients, and increasing applications of gene expression analysis in diagnostics and treatment are propelling the market growth.

Decreasing costs of gene sequencing and various technological advances, such as biochips that help in studying DNA even better, are expected to propel the market. Furthermore, increasing incidences of chronic diseases worldwide and the rise in research on developing new drugs are other prominent factors propelling the market's growth. In addition, the growing prevalence of drug discovery and pharmacogenomics in pharmaceutical companies greatly supports the gene expression analysis market. Furthermore, various applications of genomics and growing expenditure on healthcare services, especially in rural areas, are further accelerating the growth rate of the gene expression analysis market.

One of the hallmarks of the evolving genomics revolution, which is the most significant factor driving the market growth, is the development of DNA chips or also called microarrays. Glass slides have an immobilized library of genes present on a grid where each dot contains DNA from a single gene binding to messenger RNA, making, it theoretically possible to visualize the entire transcriptome in a single procedure by isolating the mRNA pool of a specific tissue, elucidating many essential research questions.

Moreover, growth opportunities for the market lie in the increasing investments by the governments in the research and development centers in biotechnology to evaluate new products at a low cost. Creating awareness of the applications of genomics and its advantages through campaigns and digital advertisements also surges the growth rate of the gene expression analysis market. In addition, the introduction of innovative procedures with the help of the latest technologies, the growing scale of pharmaceutical companies, and the increasing demand for targeted therapies are bolstering the demand for the gene expression analysis market. Rising capital income in both developed and developing countries is another attribute of gearing market growth. Reducing the cost of sequencing techniques and growing demand to evaluate quality treatment procedures are fuelling market growth.


A significant drawback that might restrain the gene expression analysis market growth is the control of background hybridization.

However, strict rules for approving the latest equipment by government organizations are quietly hampering the growth of the gene expression analysis market. Also, this equipment requires massive amounts for installation and maintenance in the laboratories, which is a challenging factor for the market players. Moreover, it is ideal to have a suitable control for each cDNA found on the array. Currently, available filter arrays do not offer these controls. Additionally, table mistakes could result from contamination in the screening procedure's clones. The need for more skilled professionals to analyze the outcomes slightly limits the market's growth rate. In addition, the lack of complete knowledge of the procedure in undeveloped countries impedes the market's growth. Therefore, the absence of skilled professionals, lack of awareness, and the high price of the instruments used for the analysis are some of the major factors restraining the gene expression analysis market.

Impact of COVID-19 on the global gene expression analysis market:

The sudden outbreak of COVID-19 has been affecting millions of people and led to devastating mortality worldwide.

Studies uncover which cell types can be infected by SARS-COV-2 due to their viral entry factors. Increasing gene expression of the viral entry factors in some individuals partially explains the differences in COVID-19 severity based on the aged elements. However, the gene expression shows that COVID-19 affects everyone in different ways. Researchers found that expression of genes underlying the increased factors in older people's cells and slightly men compared to women. Coronavirus, SARS-COV-2, majorly emerges in the lung, affecting other organs too.

The gene expression analysis market has gained momentum during COVID-19, and it is anticipated to record a better CAGR in the years to come.




Market Size Available

2021 to 2027

Base Year


Forecast Period

2022 to 2027

Segments Covered

By Technology, Consumables, Services, Application, and Region

Various Analyses Covered

Global, Regional & Country Level Analysis, Segment-Level Analysis; DROC, PESTLE Analysis, Porter's Five Forces Analysis, Competitive Landscape, Analyst Overview of Investment Opportunities

Regions Covered

North America, Europe, APAC, Latin America, Middle East & Africa


This market research report on the global gene expression analysis market has been segmented and sub-segmented into the following categories and analyzed market size and forecast until 2027.

Gene Expression Analysis Market - By Technology:

  • DNA Microarray
  • PCR
  • NGS
  • SAGE
  • Northern Blotting

Based on technology, the DNA microarray and NGS segments are anticipated to account for the most of the share in the global market during the forecast period as these are the most used technology categories. These techniques contribute a significant share to the expression analysis market. This can be attributed to the micro-level analysis of gene expression. DNA microarray uses chip-based technology that reveals gene expression and helps trace the sequence of the genes. Next-generation sequencing, also known as NGS, is a type of DNA sequencing technology that uses parallel sequencing of multiple small DNA fragments, providing opportunities for gene expression profiling in various contexts. An excellent complement to the present methodology to study specific genes' response to stimuli and discover potentially novel genes or transcripts, which has dramatically increased the speed at a decreased cost for individual genome sequencing.

Gene Expression Analysis Market - By Consumables:

  • DNA Chips
  • Reagents

Of all these segments, the DNA chips segment is expected to dominate the market during the forecast period. DNA chips are mostly preferred for analyzing the sequence of genes easily using DNA chips. A DNA chip or biochip is a microscopic DNA dots collection affixed to a solid surface, used by scientists to genotype multiple regions of a genome. To detect gene expression, also known as the transcriptome or the collection of messenger RNA (mRNA) transcripts expressed by a gene cluster, DNA molecules linked to each slide serve as probes.

The reagents segment is also anticipated to foreseen to hold a substantial market share globally during the forecast period. By cataloging the variety of mutations, these mutation detection techniques can be used to diagnose genetic disorders in both prenatal and neonatal patients and to understand the function of the afflicted protein. Here is a review of two such mutation detection methods. Both procedures involve chemically altering mismatched nucleotides, either with carbodiimide or hydroxylamine and osmium tetroxide. The techniques are known as chemical mismatch cleavage (CCM), and carbodiimide (CDI) approaches.

Gene Expression Analysis Market - By Services:

  • Gene Expression Profiling
  • Bioinformatics

Based on Services, the gene expression profiling segment holds the largest market share due to the rising number of gene expression analysis tests. Gene expression profiling is used to measure mRNA levels, which show the pattern of genes expressed by a cell at the transcription level. This sometimes entails comparing the relative amounts of mRNA produced under two or more different experimental circumstances before determining which of those circumstances led to the expression of particular genes.

The bioinformatics segment is estimated to register the fastest growth rate during the forecast period. Bioinformatics is the latest technology that is growing at a faster pace. Bioinformatics is an interdisciplinary field that involves mathematics, computer science, physics, and biology. It is the application of computational and analytical tools for interpreting biological data used by Scientists and clinicians to organize and index biological information to improve medical care and understand health and disease. The growth can be attributed to technology and devices that sequence genes using information technology and artificial intelligence.

Gene Expression Analysis Market - By Application:

  • Research
  • Drug Discovery
  • Diagnostics

Based on the application, the research segment is anticipated to lead the gene expression analysis market during the forecast period. Research is the primary market for gene expression analysis, for analyzing disease-causing organisms, and it is used in analyzing for making drugs to treat such disorders. Of all these segments, research holds a significant share. But Gene expression analysis is also being used in diagnostics at a large scale; this can be attributed to the increased rate of gene therapies. Cancer is a hereditary disease where genetic abnormalities lead to genes that act abnormally and seem to change expression. Phenotypes and biological processes are controlled by proteins, which are the result of gene expression. As a result, gene expression levels can be detected in a clinical situation to predict cancer diagnosis, prognosis, and treatment.

Gene Expression Analysis Market - By Region:

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East and Africa

Geographically, the North American gene expression analysis market is estimated to record the highest share in the global gene expression analysis market in 2020, with an estimated revenue of more than 45%. The market growth is attributed to the active participation of several key players like Thermo Fisher Scientific. In addition, the market players in this region are continuously involved in research and development activities to develop advanced technology and methods dealing with gene expression analysis.

The European gene expression analysis market is expected to be the second-largest regional market, accounting for an impressive global gene expression analysis market share. The market growth is increased by factors such as the rising interest of dominant players in the European markets. In addition, the increasing adoption of advanced technologies contributes to market growth in this region.

However, the Asia Pacific gene expression analysis market is considered one of the fastest-growing regions in the global gene expression analysis market. China and India are witnessing dominating market players; increasing investments by governments and private organizations in improving healthcare infrastructure are anticipated to create market growth in this region. As a result, India, China, Japan, and Australia are the major contributors to the Gene expression Analysis market in the APAC region.

The Latin American gene expression analysis market is predicted to grow steadily during the forecast period. The collaboration of market players and local players with foreign countries to expand their market operations increases market growth. In addition, the increasing availability of gene expression databases and the prevalence of cancer diseases in this region promote the growth of the gene expression analysis market.

The Middle East & Africa Gene Expression Analysis Market is projected to grow sluggishly during the forecast period. UAE is leading with the highest shares of the market. On the other hand, countries like Qatar are to exhibit significant developments according to their respective genomics and personalized medicine fields.


The report's promising companies leading the global gene expression analysis market are Thermo Fisher Scientific, Inc, G.E. Healthcare, QIAGEN N.V., Life Technologies, Agilent Technologies, Roche, PerkinElmer, Affymetrix, Illumina, Inc, Bio-Rad Laboratories, Oxford Gene Technology, Luminex Corporation.


  • In November 2022, an innovative biotechnology company, Silence Therapeutics plc, presented data from Phase 1 APOLLO single-dose analysis, showing maintenance of median reductions more significant than 80% in people with SLN360 single dose.
  • In November 2022, Singleton Biotechnologies, a pioneer in developing single-cell sequencing analysis solutions, launched the ProMoSCOPE kit, helping make advanced high-throughput single-cell multimodal analysis more accessible.
  • In October 2022, Oxford Nanopore Technologies plc collaborated with 10x Genomics to help users with the ability to encompass users to features like yielding rich and cost-effective single-cell and spatial sequencing data.
  • In August 2018, the NovoFocus NSCLC CDx test received CFDA approval launched by the Tianjin Novogene Bioinformatics Technology subsidiary of Novogene Co. This is a diagnostic test that analyzes tumor samples based on next-generation sequencing.
  • In January 2017, the acquisition of Biorad and RainDance Technologies was announced. The acquisition between these companies will focus on the development of droplet-based technologies digital PCR (dPCR).

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which region accounted for the largest share in the global gene expression analysis market ?

The gene expression analysis market in North America is expected to grow significantly and hold the largest share of revenue during the forecast period.

who are the key players of the global gene expression analysis market?

Thermo Fisher Scientific, Inc, G.E. Healthcare, QIAGEN N.V., and Life Technologies are some of the key market players in the gene expression analysis market

what is the compound annual growth rate (CAGR%) of the gene expression analysis market during the forecast period?

The global gene expression analysis market is expected to grow at a CAGR of 9.5% during the forecast period.

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