Immunoprecipitation Market

Global Immunoprecipitation Market Size (2023 to 2028)

The size of the global immunoprecipitation market is predicted to grow at a CAGR of 6.24% from 2023 to 2028 and be worth USD 941.01 million by 2028 from USD 695.27 million in 2023.

Global Immunoprecipitation Market Share Insights:

• Based on product, the reagents segment had the major share of the global immunoprecipitation market in 2022.
• Based on type, the individual protein segment held the leading share of the worldwide market in 2022.
• Based on end-user, the academic and research institutions segment occupied 45% of the worldwide market share in 2022.
• North America was the largest regional segment globally in 2022.

Impact of COVID-19 on the global immunoprecipitation market:

The pandemic of COVID-19 is projected to impact the market's growth positively. When the viral spike protein attaches to the ACE2 protein on the surface of human cells, the coronavirus enters the cell. Therefore, the existence of neutralizing antibodies that prevent this binding is expected to develop immunity among COVID-19-recovered patients. As a result, scientists are researching the protein interactions and activities of neutralizing antibodies. In the current COVID-19 pandemic, ChIP is critical for detecting protein-DNA interactions and understanding the SARS-Cov2 Virus's target binding sequences. As a result, the investigated segment is likely to rise significantly throughout the pandemic era as research continues in this area. Because immunoprecipitation is critical for investigating protein-DNA interactions and target binding sequences for the novel coronavirus, the COVID-19 pandemic has significantly increased its use. In addition, increased medication development research, a strong focus on COVID-19 vaccine development, developments in ChIP applications in genomic studies, and technological advancements in the ChIP method drive the worldwide immunoprecipitation market forward.

MARKET DRIVERS:

The rising prevalence of chronic diseases, growing opportunities for funding and investments in next-generation DNA sequencing and increasing R&D activities in the genomics filed by the governmental and non-governmental organizations majorly drive the global immunoprecipitation market growth. Immunoprecipitation approaches have seen considerable technological advancements. Advances in chromatin immunoprecipitation technology have resulted in Chromatrap Immunoprecipitation (ChIP) technology, a bead-free way of doing chromatin immunoprecipitation. The market is predicted to rise rapidly due to epigenetic advances made opportunities by ChIP-seq. In addition, the immunoprecipitation testing market is expected to grow due to the growing incidence of autoimmune disorders, which necessitates antibody-antigen interaction testing.

Collaborations between researchers and organizations have significantly aided the growth of the life science sector. Academic advancements in cellular and gene therapies have resulted in novel strategies for biological therapeutics. The scope of new findings is broadening due to increasing research efforts in genomics, immunotherapy, and microbiome. With advanced genetic tools, R&D for genomics for illness research, medication development, and tailored therapy design has grown steadily. In addition, many regulatory and federal agencies are launching strategic attempts to make genetic research more accessible.

The growing emphasis on personalized medicine, the expansion of the biopharmaceutical industry and rising emphasis on drug discovery and development favor the market growth. The growing awareness regarding the benefits of early disease detection and diagnosis fuels the use of immunoprecipitation techniques for biomarker identification and detection of disease-specific antibodies and the rising adoption of precision medicine supports the immunoprecipitation market growth. The growing use of antibody therapeutics for the treatment of various diseases, including cancer and autoimmune disorders, increasing focus on protein-protein interactions, rising investments for the R&D of proteomics, growing use of mass spectrometry for protein identification and characterization and increasing need for high-throughput techniques for large-scale protein analysis and screening further boost the growth rate of the immunoprecipitation market.

MARKET RESTRAINTS:

The high costs associated with immunoprecipitation reagents, antibodies and equipment are one of the major factors hampering the market growth. Lack of standardized protocols and variability in immunoprecipitation techniques, the complexity of immunoprecipitation techniques and the availability of alternative techniques for protein analysis and characterization, such as Western blotting, ELISA, and mass spectrometry hinder the market growth. The time-consuming nature of the immunoprecipitation technique, limited commercial availability of high-quality antibodies, regulatory hurdles, poor awareness and education about the benefits and applications of immunoprecipitation techniques among researchers and clinicians and compatibility issues of immunoprecipitation techniques with downstream applications, such as mass spectrometry or protein analysis platforms further limits the market’s growth rate.

REPORT COVERAGE:

This research report on the global immunoprecipitation market has been segmented and sub-segmented based on product, type, end-user, and region.

Immunoprecipitation Market – By Product:

• Kits
• Reagents
  • Antibodies
  • Beads
  • Others

Due to the widespread usage of various antibodies, beads, and buffers, the reagents segment dominated the global immunoprecipitation market in 2022. The growing use of reagents by researchers to customize their immunoprecipitation workflows by selecting specific reagents based on their requirements is one of the key factors driving segmental growth. The availability of a diverse range of immunoprecipitation reagents such as antibodies targeting different proteins, agarose beads with varied functionalities and optimized buffers and flexibility and customizability of reagents further boost the segmental growth.

On the other hand, the kits segment is predicted to grow at a promising CAGR throughout the forecast period due to the availability of a diverse product portfolio. The benefits of kits such as the convenience, time-saving benefits and standardized protocols primarily propel the segmental growth. The growing adoption of kits by academic and research institutions considering their ease of use, consistent results, and reduced training requirements further fuel the segment’s growth rate. The growing investments in proteomics research contribute to segmental growth.

Immunoprecipitation Market – By Type:

• Individual protein
• Protein complex
• Chromatin
• Ribonucleoprotein
• Tagged proteins

Based on type, the individual protein segment had the leading share of the global market in 2022 and is predicted to continue the segmental domination throughout the forecast period. The rising emphasis on protein-protein interactions research and increasing emphasis on developing new therapies and personalized medicine promote segmental growth.

On the other hand, the tagged protein segment is expected to grow at a promising CAGR during the forecast period. The growing use of tagged protein in recombinant protein expression systems for purification and detection and the significance of tagged protein in protein localization and interaction studies within cells primarily support segmental growth.

Immunoprecipitation Market – By End-User:

• Academic & Research Institutes 
• Pharmaceutical & Biotechnology Companies 
• Contract Research Organizations

Based on end-user, the academic and research institutes segment held the major share of the global market in 2022 and is predicted to grow at a healthy CAGR during the forecast period. The growing emphasis on proteomics and genomics research by academic and research institutes majorly drives segmental growth. The availability of financial resources, funding and grants by the governmental organizations to support the R&D efforts of academic and research institutes further fuel the segment’s growth rate.

The CROs segment is predicted to grow at the highest CAGR during the forecast period. The growing trend of outsourcing research activities by the pharmaceutical, biotechnology and academic institutions, cost-effective solutions and scalability in conducting research studies by CROs boost the segmental growth.

Immunoprecipitation Market – By Region:

• North America
• Europe
• Asia-Pacific
• Latin America
• Middle East and Africa

Geographically, the North American region had the largest share of the global market in 2022 and the regional domination is anticipated to continue throughout the forecast period. The availability of well-established pharmaceutical and biotechnology industries that drive demand for immunoprecipitation techniques in drug discovery and development is one of the major factors propelling the North American immunoprecipitation market. The strong presence of academic and research institutes conducting cutting-edge proteomics and genomics research and the availability of significant research funding and grants to support advancements in immunoprecipitation technology contribute to the growth of the North American market. The U.S. accounted for the major share of the North American market in 2022 and is expected to grow at a prominent CAGR during the forecast period. The rising emphasis on precision medicine and personalized healthcare, increasing demand for biomarker discovery and validation using immunoprecipitation, technological advancements and adoption of automated platforms for high-throughput immunoprecipitation analysis and growing focus on understanding protein-protein interactions for therapeutic target identification and validation in the U.S. further fuel the growth rate of the U.S. market.

The APAC immunoprecipitation market is another biggest regional segment in the worldwide immunoprecipitation market and is predicted to grow at the highest CAGR during the forecast period. Rapidly growing biotechnology and pharmaceutical industries are driving the demand for immunoprecipitation techniques in drug discovery and development in the Asia-Pacific region and propelling the APAC market growth. The growing investments for the R&D of proteomics and genomics using immunoprecipitation by academic and research institutions, the large patient population and the rising prevalence of chronic diseases promote the immunoprecipitation market growth in the Asia-Pacific region. China held the major share of the APAC market in 2022 and the same is predicted to continue during the forecast period. Technological advancements in healthcare infrastructure, rising adoption of advanced protein analysis techniques like immunoprecipitation, emphasis on precision medicine and personalized healthcare approaches, an increasing number of initiatives and funding support by the Chinese government for research and development in life sciences, including proteomics research and immunoprecipitation technology drive the Chinese market growth.

Europe immunoprecipitation market captured a considerable share of the global market in 2022 and is predicted to showcase a noteworthy CAGR during the forecast period. The growing number of research collaborations among academic institutions and biopharmaceutical companies that drive the innovation and adoption of immunoprecipitation techniques in Europe majorly support the market growth. The presence of well-established healthcare infrastructure supporting biomarker discovery and clinical proteomics research, growing investment in proteomics research and personalized medicine initiatives and strong regulatory frameworks promoting the adoption of advanced analytical techniques such as including immunoprecipitation in drug development further boost the European market growth. The United Kingdom, Germany and France collectively captured around 60% of the European market share in 2022 and the same pattern is predicted to continue throughout the forecast period. The rising emphasis on understanding epigenetic regulation and chromatin biology and the growing focus on studying post-transcriptional regulation and RNA-protein interactions favors the immunoprecipitation market in these countries.

Latin America is a noteworthy regional market for immunoprecipitation worldwide and is predicted to grow at a healthy CAGR during the forecast period. The growing investments in healthcare infrastructure and research institutions, increasing focus on understanding disease mechanisms and biomarker discovery for improved healthcare outcomes and the presence of biopharmaceutical companies and contract research organizations (CROs) offering immunoprecipitation services propel the Latin American market growth. Brazil accounted for the major share of the Latin American market in 2022.

MEA is predicted to witness steady growth during the forecast period. The growing initiatives and funding support by the governments of MEA countries for life sciences research, including proteomics and collaborative research efforts with international partners drive the regional market growth. Saudi Arabia held the major share of the MEA market in 2022.

KEY MARKET PARTICIPANTS:

Companies playing a promising role in the global immunoprecipitation market profiled in this report are Merck KGaA, Thermo Fisher Scientific, Abcam, Bio-Rad Laboratories, Abbkine Scientific Co. Ltd., Cell Signaling Technology, Rockland Immunochemicals, BioLegend, Takara Bio, GenScript Biotech Corporation, and Geno Technology.

RECENT HAPPENINGS IN THIS MARKET:

• In 2019, Merck announced plans to open a new life science center to focus on immunology, cancer, and immuno-oncology.
• In 2018, Thermo Fisher Scientific built a new bioprocess design center in Shanghai to interact with biologic developers and collaborate on developing efficient bioprocessing solutions.
• In 2019, Merck & Co. Inc. opened a new life science facility focusing on research and development activities in oncology, immunology, and immuno-oncology.
• Genscript USA, Inc. acquired FDA Emergency Use Authorization for their cPass SARS-CoV-2 Neutralizing Antibody Detection Kit in November 2020.
• In Bio-Protocol, 2020, chromatin immunoprecipitation was utilized in conjunction with quantitative PCR (Chip-qPCR) to identify DNA binding protein binding sites and detect histone modification in locus-specific regions of the genome.