Global Scaffold Technology Market Size, Share, Trends, COVID-19 Impact & Growth Analysis Report – Segmented By Type (Hydrogels, Wound Healing, Immunomodulation and 3d Bioprinting), Application (, End-Users & Region (North America, Europe, APAC, Latin America, Middle East and Africa) – Industry Forecast (2024 to 2029)

Updated On: January, 2024
ID: 12532
Pages: 190

Global Scaffold Technology Market Size (2023 to 2028)

The size of the global scaffold technology market is estimated to escalate at a CAGR of 9.12% from 2023 to 2028 and be worth USD 2.09 billion by 2028 from USD 1.35 billion in 2023.

The trend of increasingly used scaffold technology in tissue engineering and regenerative medicine research has been noticed recently. Using scaffold technology, 3D structures of extracellular matrix (ECM) of living tissues can be created, and these structures are majorly used in the in-vitro or in-vivo procedures. Using the scaffold technology, various types of tissues can also be created, such as bone, skin, cartilage, nerve, and muscle. The application of scaffold technology can also be seen in drug discovery and drug testing. Likewise, the scaffold technology has been practiced in several research areas to create functional organs and tissues that can be further used to treat various diseases. The scope, usage, and adoption of scaffold technology have grown substantially in the last few years, and the trend is expected to accelerate in the coming years.

Impact of COVID-19 on the scaffold technology market:

The pandemic has had a different impact on various sectors of society. The healthcare industry was one of the most affected sectors, among others. The epidemic has had a reasonably mixed effect on the global scaffold technology market. Tissue engineering is a process considered very effective in the study of virology. Therefore, the scaffold technology has extensively increased R&D to study and prevent the SARSCov-1 virus. Thus, the combined situation supported the growth of the market. 

On the other hand, COVID-19 has increased the need for scaffold technology, which is estimated to accelerate the market's growth rate during the forecast period.


The growing prevalence of chronic diseases contributes to the growth of the scaffold technology market.

The number of patients suffering from various chronic diseases such as osteoarthritis, diabetes, and cardiovascular diseases is growing significantly worldwide, which is propelling the need for new therapeutic solutions such as scaffold technology. Scaffold technology can help regenerate damaged cells, tissues, and organs that can help treat chronic diseases. Likewise, the growing patient count suffering from chronic diseases is anticipated to boost the demand for scaffold technology and offer a significant opportunity for the market players to develop new and innovative scaffold technologies to address the growing demand.

The growing global aging population is expected to fuel the scaffold technology market growth.

With growing age, people are much more prone to various chronic and other diseases. Especially the incidence of arthritis, Parkinson's disease, and Alzheimer's can be seen among the elderly, which needs tissue regeneration. As per the data published by the World Health Organization (WHO), 1 in every 6 people are expected to be aged 60 years and more by 2030, and the total population of the aged will reach 1.4 billion by 2030. Therefore, organ failures can be seen more in the elderly and require transplantation procedures. Moreover, the world is facing a significant organ shortage, and people waiting on the organ list are growing substantially. In such situations, scaffold technology can help create functional organs and tissues for organ transplantations.

The growing investments to conduct R&D around scaffold technologies by the market participants are anticipated to fuel the market’s growth rate. The demand for tissue engineering and regenerative medicine is growing significantly, and the adoption of scaffold technology in tissue engineering and regenerative medicine has increased notably recently. To meet the growing demand, the market participants invest significant amounts of R&D in developing new and innovative scaffold technologies and collaborating with academic institutions and research institutes.

The growing adoption of 3D printing in the healthcare industry is expected to boost the scaffold technology market growth.

The penetration of 3D printing technology in scaffold fabrication has increased over the last few years. The growing usage of 3D printing technology in tissue engineering is anticipated to increase demand for scaffold technology. The growing advancements in biomaterials are expected to favor the growth rate of the scaffold technology market. Biomaterials play a vital role in scaffold fabrication, and the development of new biomaterials with improved biomaterials is expected to result in the growing demand for scaffold technology. In addition, the growing number of organ transplantation procedures worldwide is expected to support the scaffold technology market growth. The world is facing a shortage of organs, and people waiting for organ transplants are growing significantly. Using scaffold technology, the creation of functional tissues and organs for transplantation is possible. In addition, the growing demand for personalized medicine is predicted to fuel the growth rate of the scaffold technology market.


The new scaffold-free cell culture technology being introduced in the multi-dimensional cell culturing market and the increment in the costs for implementation are expected to hinder the growth of the scaffold technology market. However, the high costs associated with the manufacturing of scaffold materials and the development of scaffold technologies are one of the key factors hampering the scaffold technology market growth. In addition, lack of standardization and poor availability of raw materials are further hindering the market growth. Furthermore, the complicated regulatory environment of tissue engineering and regenerative medicine is expected to have an unfavorable impact on the scaffold technology market.




Market Size Available

2022 to 2028

Base Year


Forecast Period

2023 to 2028

Segments Covered

By Type, Application, End-Users & Region

Various Analyses Covered

Global, Regional & Country Level Analysis, Segment-Level Analysis, Drivers, Restraints, Opportunities, Challenges; PESTLE Analysis; Porter’s Five Forces Analysis; Competitive Landscape, Analyst Overview of Investment Opportunities

Regions Covered

North America, Europe, Asia Pacific, Latin America, the Middle East, and Africa


This market research report on the global scaffold testing market has been segmented and sub-segmented based on the type, application, end-users & region.

Global Scaffold Technology Market - By Type:

  • Hydrogels 
    • Micropatterned Surface Microplates
    • Polymeric Scaffolds
    • Nanofiber-Based Scaffolds
  • Wound Healing
  • Immunomodulation
  • 3d Bioprinting

In 2022, the hydrogels segment accounted for the most significant share of 44% of the scaffold technology market based on type, emerging as a prominent sector. Shortly, it is anticipated that ongoing technological developments in the microfabrication of hydrogels will accelerate segment growth. In addition, companies are also introducing fresh hydrogels for drug depots, restenosis barriers, and cell transplantation.

Global Scaffold Technology Market - By Application:

  • Drug Discovery
  • Stem Cell Therapy, Regenerative Medicine, & Tissue Engineering
  • Others

Based on the application, the stem cell therapy, regenerative medicine, and tissue engineering segment dominated the scaffold technology market in 2022, with a share of more than 60%. The expansion is linked to the increasing use of scaffold technology in periodontology, colorectal surgery, soft tissue tumor repair, cosmetic surgery, abdominal wall repair, and reconstructive procedures.

On the other hand, the drug discovery segment is anticipated to rise significantly throughout the forecast period. The demand for scaffold technology in this segment has been driven by the necessity to create reliable and transportable tools for the study of biomedical science, including drug discovery and therapeutic development. 

Global Scaffold Technology Market - By End-User:

  • Hospitals And Diagnostic Centers
  • Research Laboratories and Institutes
  • Biotechnology And Pharmaceutical Industries
  • Others

With a share of 51% in 2022, the biotechnology and pharmaceutical industries segment dominated the market for scaffold technology. The extensive use of scaffold technology by these companies in tissue engineering sectors such as periodontal regeneration, cartilage development, bone creation, repair of nasal and auricular deformities, tendon repair, and heart valves is what is responsible for the segment's growth. In addition, biotechnology businesses are working together to create new synthetic scaffolds.

Scaffold Technology Market – By Region:

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East and Africa

In 2020, North America held the most significant revenue share of 40.6 percent in the market for scaffold technology, and it is anticipated that this dominance will last during the forecast period. The existence of well-known players in this area fuels its rise. Additionally, businesses in this area are introducing brand-new, cutting-edge solutions to aid in advancing 3D cell culture in countries like the U.S. and Canada, another factor contributing to the region's expansion.

Over the coming years, scaffold technology is anticipated to have profitable expansion in Asia-Pacific. The area's development is attributable to governmental institutions carrying out stem cell and regenerative medicine research. For instance, the Indian Council of Medical Research and the Ministry of Science and Technology prioritize stem cell and regenerative medicine research in India. Furthermore, the National Centre for Cell Science's research in stem cell biology and other areas of advanced medicine is anticipated to enhance the use of scaffold technology in the nation and countries like China, Japan, and South Korea.


Corning Incorporated, Bioquote Ltd, Avacta Life Sciences Limited, Nanofiber Solutions, Vericel Corporation, Allergen, NuVasive, Pelobiotech, 4titude, Molecular Matrix Inc., REPROCELL Inc, Xanofi, Tecan Trading AG, Thermo Fisher Scientific Inc, Becton Dickson and Company, Merck KGaA, 3D Biotek LLC, Nanofiber Solutions, Vericel Corporation, Akron Biotech, Bioquote Ltd are some of the major players in the global scaffold technology market profiled in this report.


  • In June 2022, in a recent article, scientists from the Boston University School of Medicine (BUSM) provided thorough information on mass spectrometry-based studies on neurological disorders, such as A.D., P.D., and S.Z., explicitly focusing on the expression of the brain's ECM components, opening doors for therapeutic approaches and treatment plans that will benefit patients with these disorders.
  • The brain's extracellular matrix (ECM) is a vast network of proteins and other chemicals that surround, support, and give structure to cells and tissues and are crucial for cell growth, migration, and other processes. The neuropathophysiology of illnesses, including Alzheimer's disease (A.D.), Parkinson's disease (P.D.), and schizophrenia (S.Z.), which affect an increasing percentage of the population, is also influenced by the ECM.
  • In June 2022, A novel 3D printing platform could help advance the development of artificial heart valves. Researchers have created scaffolding for prosthetic heart valves that match the various biomechanical features of heart valve tissue using a revolutionary 3D printing technique called melt electrowetting. Researchers at the Technical University of Munich (TUM) in Germany can combine numerous, exact bespoke patterns in the scaffold and adjust its mechanical properties so that the patient's cells generate new tissue as the scaffold degrades. Hopefully, this technology will result in lifelong pediatric implants that needn't be replaced.
  • CELLINK GLOBAL joined the TRIANKLE consortium in November 2020 to develop novel individualized gelatine and collagen-based implants for ankle joint tissue regeneration using 3D printing technology.
  • A reusable 3D cell culture microplate was launched by eNuvio, a Canadian company, in December 2020.
  • United Healthcare's MACI (autologous cultured chondrocytes on porcine collagen membrane) medical insurance was extended in January 2021 to cover persons with numerous cartilage abnormalities in the knee and patella.

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Frequently Asked Questions

What was the value of the scaffold technology market in 2022?

The global scaffold technology market size was valued at USD 1.24 billion in 2022.

How does COVID-19 impacted the scaffold technology market?

COVID-19 is currently showing a mixed impact on the scaffold technology market. However, the future of the market is expected to be bright.

Which region accounted for the major share in the global scaffold technology market?

Geographically, North America was the leading region in the global scaffold technology market and registered a share of 40% of the global market in 2022.

Who are some of the major players in the scaffold technology market?

Thermo Fisher Scientific, Inc., Merck KGaA, Tecan Trading AG, REPROCELL Inc., 3D Biotek LLC, Becton, Dickinson, and Company, Medtronic, Xanofi, Molecular Matrix, Inc. are a few of the notable players in the global scaffold technology market.

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