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Global Ion Chromatography Market Size, Share, Trends, COVID-19 Impact & Growth Analysis Report – Segmented By Technology, Application & Region – Industry Forecast (2022 to 2027)

Published: March, 2023
ID: 12362
Pages: 190
Formats: report pdf report excel report power bi report ppt

Global Ion Chromatography Market Size (2022 to 2027)

The global ion chromatography market is predicted to rise at a CAGR of 7.02% during the forecast period and the market size is expected to grow from USD 3.17 billion in 2022 to USD 4.45 billion by 2027.

Global Ion Chromatography Market Share Insights:

  • Based on technology, the ion exchange segment had the major worldwide market share in 2021.
  • Based on application, the pharmaceutical segment occupied the largest share of the global market in 2021.
  • North America was the leading share of the global market in 2021.
  • The European region captured the second-largest worldwide market share in 2021 and is expected to be valued at USD 1.29 billion by 2027.
  • The Asia-pacific is estimated to hold a considerable share of the global market in the coming years and progress at a CAGR of 8.96%.

Ion chromatography is an effective method to determine the concentrations of anions and cations in liquid, gaseous, and solid samples. Regulatory analysis techniques have been devised utilizing this methodology by organizations such as the ISO, US EPA, ASTM, and AOAC. In ion chromatography, the two detection methods currently used are electrochemical and spectrometric. Based on the nature of the charge present on the ion, there are two types of ion exchange chromatography procedures. Anion exchange chromatography and cation exchange chromatography are the two methods. Ion exchange resins can be used as pharmaceutical carriers and in slow-release applications. For example, Cholestyramine is a dried and ground strong base anion resin that helps to reduce blood cholesterol by binding bile acid.

Impact of COVID-19 on the global ion chromatography market:

COVID-19 was announced as a pandemic by the World Health Organization (WHO) and hampered the world economy badly. Many governments worldwide have taken several measures such as lockdowns, travel bans, social distancing, and temporary shutdowns to curb the spread of the coronavirus. As a result, COVID-19 has had a significant negative impact on the worldwide ion chromatography market. Ion chromatography is used in various applications such as healthcare, F&B, and others. Due to COVID-19, the F&D industry has seen severe negative impacts, such as supply chain disruptions and halted manufacturing and business activities. However, the global ion chromatography market is expected to recover quickly and register a healthy CAGR in the coming years owing to the factors such as the declining impact of the COVID-19 pandemic and growing habituation towards new normalization.


The growing usage of ion exchange chromatography for purification and the growing need for monoclonal antibodies propel market growth.

Protein A affinity chromatography is more expensive; the process becomes more expensive. Various attempts are being made to make the process more cost-efficient. Using two-column ion exchange (cation and anion exchange) chromatography is one of the most successful ways. The global ion chromatography market is being driven by the growing use of ion exchange chromatography for purification and the increasing demand for monoclonal antibodies. Over the last decade, the use of monoclonal antibodies has skyrocketed, and estimates imply that mAbs and their variants account for over a third of all biopharmaceuticals in development, including vaccines and gene therapy. Biopharmaceutical goods must be pure, as any impurity can substantially impact the body's response to the medicine and cause various unneeded difficulties. Typically, a three-column chromatography technique is used to achieve this high level of purification.

One of the key advantages of ion exchange chromatography is that there is only one interaction in the separation: the analytical species interacting with the stationary phase. Because of the vast range of applications and connected markets, ion exchange chromatography has the largest market share. During the forecast period, this market share is expected to grow even more. Technology plays a vital role in product development and improvement. Advances in ion chromatography provide a massive opportunity for the market to cater to many applications, including environmental and chemical analysis. Furthermore, artificial intelligence and automation have already begun to be implemented at a greater level in the industry. As a result, data analysis should be significantly faster and more precise as AI and automation are combined. 

The recent advancements and growing ease in the process of ion chromatography are anticipated to favor the market's growth rate during the forecast period. For instance, the introduction of a new type of organic polymers, the reduction of the diameter of the tube, the rising capacity of ion exchange, growing column efficiency, new chemical layers in the tubes, introduction of reagent-free ICs and monolithic columns for liquid chromatography and others, driving the market growth. 


The global market for ion chromatography is projected to be hampered by the high equipment cost. Another aspect impeding the market is a scarcity of skilled personnel to operate the equipment. In addition, obtaining budget approvals for significant capital expenditures is frequently considered challenging.




Market Size Available

2021 to 2027

Base Year


Forecast Period

2022 to 2027

Segments Covered

By Technology, Application & Region

Various Analyses Covered

Global, Regional & Country Level Analysis, Segment-Level Analysis, Drivers, Restraints, Opportunities, Challenges; PESTLE Analysis; Porter's Five Forces Analysis; Competitive Landscape, Analyst Overview of Investment Opportunities

Regions Covered

North America, Europe, Asia Pacific, Latin America, Middle East & Africa


This research report on the global ion chromatography market has been segmented and sub-segmented based on technology, application, and region.

Ion Chromatography Market – By Technology:

  • Ion-exchange Chromatography
  • Ion-exclusion Chromatography
  • Ion-pair Chromatography

Based on technology, the ion exchange segment is anticipated to capture the most significant share of the worldwide market during the forecast period. The growing adoption of ion-exchange technology in various industries such as F&D, wastewater, and other industries to evaluate quality and safety primarily contributes to segmental growth.

On the other hand, the ion-pair chromatography segment is also expected to witness considerable growth during the forecast period due to its several advantages, such as the ability to segregate ionized and non-ionized molecules simultaneously along with its precision and fast detection capability, which enables it to be used in multiple sectors.

Ion Chromatography Market – By Application:

  • Environmental Testing
  • Pharmaceutical Industry
  • Food Industry
  • Chemicals Industry
  • Other Applications

Based on the application, the pharmaceutical industry is expected to grow at the fastest CAGR over the forecast period. Ion chromatography is an extensively utilized analytical technique for characterizing new drug ingredients and therapeutic products in the pharmaceutical segment. It is used throughout the process, from method development to dosage analysis. The approach has made sample analysis more comfortable in recent years. Because it may be done overnight with multiple samples, this process saves a lot of time and money. In addition, small molecules or giant molecules, such as proteins, can be analyzed.

However, the food segment is anticipated to hold a considerable share of the worldwide market during the forecast period owing to the growing usage of ion chromatography in the F&B industry to test the impurities of F&B products. Furthermore, the increasing need to eliminate the diseases associated with food and water further propels segmental growth. In addition, the stringent government regulations around F&B packaged products favor the segment's growth.

Ion Chromatography Market – By Region:

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • The Middle East and Africa

Geographically, the North American ion chromatography market captured the largest share of the worldwide market and is estimated to continue leading during the forecast period. The growing focus on limiting the incidence of diseases that spread through consuming poor-quality food and water is accelerating regional market growth. In addition, the presence of well-established healthcare infrastructure and key market participants, and increasing investments from the market participants to conduct R&D in this space promote regional market growth. Furthermore, the stringent regulations imposed by the North American governments favor the growth of the North American market. The emergence of novel ion separation techniques and rapid adoption of technological advancements are further fueling the growth rate of the North American market. The U.S. led the North American market in 2021, followed by Canada.

During the forecast period, the European ion chromatography market is expected to have promising growth owing to the increasing R&D activities. In addition, the increasing healthcare infrastructure is promoting regional market growth. As a result, countries such as the UK, Germany, and Italy are expected to hold a significant share of the European market during the forecast period.

The APAC ion chromatography market is estimated to grow at the fastest CAGR during the forecast period. Several market participants are investing considerably in the Asia-Pacific region to conduct R&D around ion chromatography, which is one of the key factors driving the APAC market growth. From Asia-Pacific, the Japanese market is anticipated to hold a considerable share of the regional market during the forecast period; China is anticipated to witness a healthy CAGR in the coming years. The growing adoption of ion chromatography techniques in this region's F&D and pharmaceutical industries is supporting the APAC market's growth rate. In addition, the rising wwaterpollution and air pollution levels are contributing to the growth of the APAC market.

The Latin American ion chromatography market is expected to hold a considerable share of the worldwide market during the forecast period.

The ion chromatography market in MEA is forecasted to grow at a moderate CAGR in the coming years.


Thermo Fisher Scientific, Metrohm, Qingdao Shenghan, Tosoh Bioscience, Shimadzu, Qingdao Ion Chromate Tograph, MembraPure, Mitsubishi Chemical Analytics, Qingdao Puren Instrument, East & West Analytical Instruments, Qingdao Luhai, Sykam, and Cecil Instruments are some of the prominent companies operating in the global ion chromatography market.


  • In June 2020, Waters Corporation announced Waters Arc HPLC System, a new HPLC for testing in the pharmaceutical, food, academic, and materials markets.
  • Researchers from the University of Verona in Italy announced in July 2020 that they had developed and validated a liquid chromatography-tandem spectrometry (LC-MS/MS) technique for simultaneously quantifying 15 bile acids species in serum samples.
  • Thermo Fisher released a new high-pressure ion chromatography system that improved performance in February 2018.

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How big is the global ion chromatography market?

As per our research report, the global ion chromatography market size is projected to be USD 4.1 billion by 2027.

Does this report include the impact of COVID-19 on the ion chromatography market?

Yes, we have studied and included the COVID-19 impact on the global ion chromatography market in this report.

Which region led the ion chromatography market in 2021?

Geographically, the North American regional market dominated the ion chromatography market in 2021.

Which are the significant players operating in the ion chromatography market?

Companies playing a major role in the global ion chromatography market are Thermo Fisher Scientific, Metrohm, Qingdao Shenghan, Tosoh Bioscience, Shimadzu, Qingdao Ion Chromate Tograph, MembraPure, Mitsubishi Chemical Analytech, Qingdao Puren Instrument, East & West Analytical Instruments, Qingdao Luhai, Sykam, and Cecil Instruments.

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