North America Protein A Resins Market Research Report – Segmented By Product Type, Application, End Users, Matrix Type & Country (The United States, Canada and Rest of North America) - Industry Analysis on Size, Share, Trends, COVID-19 Impact & Growth Forecast (2024 to 2029)

Updated On: January, 2024
ID: 338
Pages: 145

North America Protein A Resins Market Size (2023 to 2028)

The Protein A Resins Market size in North America was worth USD 194.30 million in 2023 and is estimated to be growing at a CAGR of 7.5% to reach USD 278.95 million by 2028.

The demand for protein A resins in the region rises as research and development efforts for new drug development increase. In most drugs discovery and approval procedures, chromatography using protein A resin has been utilized to capture monoclonal antibodies (mAb). In addition, protein A’s productivity, capacity, and operating velocity have improved in recent years, expanding its utility in drug development even more. 

Furthermore, as the number of people suffering from chronic diseases grows, investment in drug research is expected to result in a larger market. As a result, immunoprecipitation is used in research and development for protein purification. IP is a precise and effective approach for separating target antigens from crude cell lysates for analytical purposes. Moreover, protein A resin is used in Ip to remove immunological complexes that develop between an antigen and its particular antibody. As a result of the increasing use of immunoprecipitation, the segment is expected to increase rapidly.

The growing usage of chromatography techniques in chemical and biological disciplines will boost the protein A resins market in North America. Chromatography is a technique for isolating biological substances and identifying chemicals and biologicals. Chromatography is fast gaining popularity due to the wide range of advantages it provides over traditional approaches. Protein A resin is the most common affinity resin used in biomanufacturing, and it has become the industry standard for collecting recombinant mAb. The superiority and dependability of chromatography will drive protein A resins market size in the coming years.

The market for protein A resins in the North American region is projected to be restrained by increased awareness of alternative methods for purifying monoclonal antibodies. In addition, the high cost of protein A resin is a major restrain to the market growth. 

This research report on the North America Protein A Resins market has been segmented and sub-segmented into the following categories:

By Product Type: 

  • Natural Protein A Resin
  • Recombinant Protein A Resin

By Application: 

  • Immunoprecipitation
  • Antibody Purification

By Matrix Type: 

  • Glass or Silica
  • Agarose
  • Organic Polymer  

By End Users: 

  • Biopharmaceutical Manufacturers
  • Clinical Research Laboratories
  • Academic Institutions

By Country: 

  • The United States
  • Canada
  • Rest of North America

Geographically, the North American regional market held the largest share of the global protein A risen market in 2020. The regional market growth is attributed to the increasing technological developments and research and development efforts, including the availability of advanced healthcare infrastructure, favorable reimbursement policies, and increasing healthcare spending. Recombinant protein A resins are projected to gain traction among end-users in the United States and Canada. Through geographic expansion in the United States, stakeholders are expected to increase their market presence in North America. Product acceptance in the country will be aided by increasing technology developments and increased research and development efforts.

The United States market is anticipated to witness the largest share of the North American protein A risen market during the forecast period. The market growth is expected to be driven by the prevalence of chronic diseases, product approvals, and research and development activities. In addition, protein therapeutics will be manufactured faster due to vital initiatives done by scientific associations. As a result, the revenue share of the protein A resins business in the United States was estimated to be over 85 percent in 2019 and is expected to grow rapidly by 2028.

As drug research activities have stepped up in recent years, Canada will likely see a surge in investment. It’s worth noting that immunotherapy has become increasingly popular in the region. As a result, the Canadian protein A resins market is predicted to grow at a substantial CAGR of 8.5%.


Key players in the market enter into strategic agreements to develop raw materials required to manufacture Protein A resins. As a result, GE Healthcare, Repligen Corporation, Novasep, Tosoh Bioscience, GenScript, Thermo Fisher Scientific and EMD Millipore, and Expedeon Ltd dominate North American protein A resins market.

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