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Global Label Free Detection Market Size, Share, Trends, COVID-19 Impact & Growth Analysis Report – Segmented By Technology, Product Type, Application & Region – Industry Forecast (2022 to 2027)

Published: January, 2022
ID: 2832
Pages: 175
Formats: report pdf report excel report power bi report ppt

Global Label Free Detection Market Size (2022 to 2027)

As per our research report, the global label free detection market is estimated to grow at a CAGR of 11.99% during the forecast period. The market size is predicted to value USD 3.18 billion by 2027 and USD 1.8 billion in 2022.

LFDs (Label-Free Detection) is a technique for detecting biomolecules and their interactions without labels. The LFD method has made significant progress due to material science, computational design, and nanofabrication expertise. Label-free detection methods are widely utilized to get analytical data without dyes, specialized reagents, or reporter labels. These technologies offer a fast and real-time way to discover novel drugs. In addition, biochemical and cell-based tests are often detected using label-free detection. The increased demand for label-free detection techniques is due to a growth in outsourcing pharmaceutical activities and R&D activities by academic institutions. Because they efficiently handle the complexity of many signaling pathways, these techniques are in great demand.


Innovations in unlabelled detection technologies and increased drug discovery programs through research partnerships between pharmaceutical companies and academic institutions drive the growth of the global label free detection market.

The growth of the pharmaceutical and biotechnology industries, the development of more sensitive non-marker technologies, and the increase of life sciences research activities in emerging markets are further anticipated to promote the growth rate of the label free detection market. In addition, introducing technologically advanced products and increasing the prevalence of effective product delivery favor market growth. The label-free detection market provides many opportunities for probing interactions of the molecules without the quenching effects of labels.

Companies leading the global label free detection market, such as AstraZeneca, GlaxoSmithKline, Sanofi, and Johnson & Johnson, have also announced plans to invest in R&D activities in emerging markets in coming years. These increasing investments in emerging markets are escalating research and development activities, presenting growth opportunities for market players.


The expensive nature associated with the instruments required for label free detection is majorly hampering the market growth. Furthermore, poor awareness regarding the benefits of label free detection is another significant factor restricting the global label free detection market growth from unleashing its full potential.

Impact of COVID-19 on the global Label-Free Detection Market:

As per the research at the ETH Zurich of Switzerland, a demonstration of the LSPR (Localized Surface Plasmon Resonance) with the highest accuracy and sensitivity is used to detect RNA COVID-19. In label-free detection surface plasmon, Resonance is the market's primary technique and growth percentile indicator. For COVID-19 research, label-free products, like SPR systems and biosensors, are also used. Unfortunately, nearly 44% of clinical trials were closed due to the pandemic for a few months. However, the market players are coming up with different strategies to fight against coronavirus to help gain profits during the coming years. 




Market Size Available

2021 to 2027

Base Year


Forecast Period

2022 to 2027

Segments Covered

By Technology, Product Type, Application, and Region

Various Analyses Covered

Global, Regional & Country Level Analysis, Segment-Level Analysis; DROC; PESTLE Analysis; Porter's Five Forces Analysis, Competitive Landscape, Analyst Overview of Investment Opportunities

Regions Covered

North America, Europe, APAC, Latin America, Middle East & Africa


This research report on the global label free detection market has been segmented and sub-segmented based on technology, product type, application, and region.

Label Free Detection Market - By Technology:

  • Bio-layer Interferometry
  • Cellular Dielectric Spectroscopy
  • Optical Waveguide Grating Technology
  • Surface Plasmon Resonance

The surface plasmon resonance segment accounts for segment technology's significant share of the label-free detection market. It has factors like the high technology sensitivity and wide usage in determining the specialties and kinetic parameters during the micro-molecule binding. The technology segment is divided into Isothermal Titration Calorimetry, Surface Plasmon Resonance, Differential Scanning Calorimetry, and Bio-layer Interferometry.

Label Free Detection Market - By Product Type:

  • Consumables Such as Biosensor Chips
  • Microplates
  • Instruments

The biosensor chips segment accounted for the most significant portion of the consumables market based on the product type. This is due to their high specificity and real-time ability to observe molecular interactions.

Label Free Detection Market - By Application:

  • Binding Kinetics
  • Binding Thermodynamics
  • Endogenous Receptor Detection
  • Hit Confirmation
  • Lead Generation

The application segment also contributes to a significant share in the label-free detection market due to advantageous factors.

Label Free Detection Market - By Region:

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East and Africa

Geographically, the North American region accounted for a significant portion of the global market, followed by the European countries and the Asia-pacific region in 2021. The presence of key market participants, growing R&D activities, and availability of funds are a few factors promoting the label free detection market in the North American region.

The market in the APAC region is estimated to register the highest CAGR during the forecast period. The growth of Asian economies, especially China and India, and growing biotechnology industry in this region, and increasing drug discovery investments are driving the label free detection market in Asia. Most Asian countries have not created business models but have the scientific talent to develop solid local biotech industries. In addition, many Asian economies have modified regulations, policies, and guidelines to support investment, innovation, and commercialization. As a result, research activities in the life sciences sector are increasing.

The United Kingdom held the largest share of the label free detection market in Europe due to an increasing number of pharmaceutical and biotechnology companies. France and Spain are next to the UK in holding the share with the rise in legal take of new approaches to discovering drugs. In addition, initiative steps by the government and growing R & D activities in these countries are likely to bolster the market demand. In some areas, constant economic growth also presents opportunities for the label-free detection market in this region.


Key participants playing a promising role in the global label free detection market profiled in this report are Ametek, Inc., Bio-Rad Laboratories, Inc., BiOptix, Corning, Inc., Danaher Corporation, General Electric Corporation, Pall Corporation, PerkinElmer, Attana AB, and Roche.


  • In April 2019, the TA instruments launched ElectroForce 3300 series III. The flexible and powerful instrument helps achieve high efficiency in testing materials.
  • In Feb 2019, Hitachi High-Technologies Corporation and Asia Clean Capital Limited became one, i.e., they collaborated in the distribution of solar power projects to develop Japanese enterprise operations in the Chinese market. 
  • In June 2018, Bruker Corporation completed the acquisition of sierra sensors Gmbh to expand its product portfolio.
  • In Aug 2017, Malvern Panalytical, a global leader, announced a collaboration with TetraScience partnership, a computer network providing Internet of Things (IoT) company, to deploy the IoT-enabled power to do something interconnected with the instruments. In addition, the collaboration aims to provide access to dashboards, data collection and analytics, and system scheduling and monitoring.

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How much was the global label free detection market worth in 2021?

The global label free detection market size was worth USD 1.61 billion in 2021.

Which segment by technology dominated the label free detection market in 2021?

The surface plasma resonance segment had the major share in the global label free detection market in 2021.

Which region is anticipated to grow the fastest in the global label free detection market?

Geographically, the Asia-Pacific region is expected to showcase the fastest CAGR in the global market during the forecast period.

What are some of the notable players in the label free detection market?

Ametek, Inc., Bio-Rad Laboratories, Inc., BiOptix, Corning, Inc., Danaher Corporation, General Electric Corporation, Pall Corporation, PerkinElmer, Attana AB, and Roche are a few of the noteworthy companies in the label free detection market.

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