Aptamers Market

Global Aptamers Market Size (2022 to 2027)

The global aptamers market size is estimated to value USD 242.3 million in 2022 and grow USD 523.5 million by 2027, growing at a CAGR of 16.66 % during the forecast period.

Aptamers are oligonucleotides that bind to a target protein, lipid, or nucleic acid molecules with high specificity. Aptamers are generated quickly and applied in the inhibition, characterization of proteins, and specific detection and can be used as pharmaceutical leads, functional proteomic levels with antibodies, detection reagents, and small molecules. Aptamers can be engineered to have higher specificity and affinity for several targets.

The key players' enormous opportunities are drug discovery, biomarker discovery, and diagnostics segments. The launch of Macugen, the first aptamer drug and the first diagnostic test for testing mycotoxins in grains, has recognized the potential of aptamers in diagnostics and therapeutics. The global market for aptamers is expected to grow, backed by technological advancements concerning selection processes and synthesis.

MARKET DRIVERS:

The primary factors driving the growth of the global aptamers market are technological advancements and increasing R & D investments in the pharmaceutical and biotechnology industries.

Low cost and high efficacy in binding to large molecules compared to antibodies and the patent expiration of systematic evolution of ligands by exponential enrichment technology (SELEX) will positively boost this market.

Additionally, factors such as betterments in the development technologies of aptamers, growing investments for the R&D by the key market players to develop and produce recombinant products are supporting the global aptamers market. Increasing the aptamers for drug discoveries and disease treatment may enhance market growth during the forecast period. Growing FDA approvals for the first aptamers drug is expected to drive market growth during the forecast period. Increasing awareness by producers and encouraging pipeline are escalating market growth. Less cost of the aptamers market, growing research, and development investments towards biotechnology and pharmaceutical sectors boost the aptamers market growth globally.

The growing adoption of aptamers in chemical and food industries and increasing demand among the public for the aptamers due to their benefits, such as their high efficiency and low cost compared to antibodies, are further expected to drive the global aptamers market.

MARKET RESTRAINTS:

Stringent regulations in the use of aptamers, Ethical issues of the aptamers obtained from the animals, slow in reaching the marketplace due to regulatory hurdles, hinder the market's growth. Furthermore, the Lack of proper regular guidelines on molecular development hinders the overall growth during the period. The shortage of trained and expert professionals may obstruct the aptamer's growth. Less market acceptance restricts the market growth during the forecast period. Low awareness about the latest technologies in middle and low-income countries and insufficient regulatory structure impedes growth globally. Many aptamers have failed to meet the required safety and efficiency standards over the clinical studies during the forecast period. Unfavorable characteristics of the aptamers obstruct the growth.

Impact of COVID-19 on the global aptamers market:

As COVID-19, which SARS-CoV-2 causes, continues to infect millions of people worldwide, the race to develop new diagnoses, treatment, and preventive measures is more important than ever. To build a complete management regimen, a framework of diagnostics, treatments, and, most critically, vaccinations are being developed.

Aptamer, a single-stranded folded RNA or DNA that can bind and detect different nucleic and non-nucleic acid compounds with great affinity and specificity, is one of the new DNA receptors. In recent years, the use of aptamer probes for viral detection has grown. Aptamers, which are multipotent biological probes, might be great choices for developing sensitive and specific biosensors. Although just a few types of research have focused on specific coronavirus aptamer types, they may aid in determining the optimal method for obtaining particular aptamers for this virus. Any viral infection sign, including viral genes, proteins, and antibodies, might be detected using aptamers. Aptamers may be beneficial in this pandemic because they may be used to both screens for and treat COVID-19, which is particularly beneficial given the limitations of existing techniques due to resource and equipment availability. Considering the aforementioned factors, the global aptamers market is expected to showcase healthy growth during the forecast period.

REPORT COVERAGE:

This research report on the global aptamers market has been segmented and sub-segmented based on the type, application, end-user, and region.

Aptamers Market - By Type:

• Peptide Aptamers
• Nucleic Acid Aptamers
  • DNA-Based Aptamers
  • RNA-Based Aptamers
  • XNA-Based Aptamers

Based on type, the DNA-based aptamers segment dominates the global aptamer market concerning product type and contributes a significant share of revenues to the market. This segment is likely to grow at an ample pace during the forecast period due to increasing research and development initiatives on DNA-based aptamers.

Aptamers Market - By Application:

• Therapeutics Development
• Diagnostics
• Research and Development

The Diagnostic segment has contributed a significant share of revenues to the recent past aptamers market based on the application. It is anticipated to be growing rapidly due to a continually increasing population with various diseases leading to a boost in demand for different diagnostic techniques.

Aptamers Market - By End User:

• Pharmaceutical Companies
• Bio-Pharmaceutical companies
• Academic and Research Centres

Based on end-user, the academic and research institutes segment has contributed significantly to the recent years. It is likely to grow further during the forecast period.

Aptamers Market - By Region:

• North America
• Europe
• Asia Pacific
• Latin America
• The Middle East and Africa

Regionally, North America dominates the global Aptamers market with the highest share, followed by Europe Asia - Pacific. Asia-Pacific is expected to account for the highest growth during the forecast period.

North America was the leader in the global aptamers market in 2019 and is expected to continue growing throughout the forecast period. This region is strongly driven by factors such as advancements in technology and increasing R&D activities. The United States is playing a leading role in the North American market owing to the favorable government initiatives and a rising number of research laboratories.

The aptamers market in the European region is ranked as the second-largest region in the global market. The increasing number of approvals for existing advanced technologies, the rising occurrence rate of chronic diseases, and the growing demand for therapies of aptamers in Europe actively support market growth. It is likely to be at the forefront and advanced within a short period of time in the forthcoming years. This region's growth is attributed to increasing approvals for existing advanced technologies, increasing the occurrence rate of chronic diseases, and growing demand for therapies of aptamers of this region.

The growth of the aptamers market in the Asia-Pacific market is driven by the collective efforts of the key players of the developed regions to push into untapped markets. Increasing R & D investments in the pharmaceutical and biotechnology industries also bolstered the aptamers market growth during the forecast period. Furthermore, factors such as combined efforts taken by the key players of the developed regions to push into untapped markets, fueling the market. Increasing research and development investments in the pharmaceutical and biotechnology industries also bolsters the aptamers market growth during the forecast period.

Latin America, Middle East, and Africa regions are likely to have a stable growth rate during the forecast period. Latin American growth is expected to drive by the improvements in aptamer development technologies; many companies investing in this market are accelerating the market. These aptamers have failed to meet the needs of protected and efficient standards in clinical studies of the market.

The aptamers market in the Middle East & Africa region is anticipated to have significant shares due to technological advancements. However, strict regulations for aptamers' usage and ethical issues for aptamers hamper the market growth in this region.

KEY MARKET PLAYERS:

Companies leading the global aptamers market profiled in the report are AM Biotechnologies, Aptagen, Aptamer Sciences Inc., Aptamer Solutions Ltd, Aptus Biotech S.L, Base Pair Biotechnologies Inc., NeoVentures Biotechnology Inc., SomaLogic Inc., TriLink BioTechnologies Inc., and Vivonics, Inc.

NOTABLE HAPPENINGS IN THIS MARKET IN THE RECENT PAST:

• In February 2019, Base pair biotechnologies Inc. developed the point-of-care tests to diagnose neonatal abstinence syndrome based on aptamer with the SBIR grant's assistance.
• In January 2019, Aptamer Group announced that the AstraZeneca Company has agreed to collaborate to expand the aptamer technology application potential. With this collaboration, AstraZeneca will adapt to the aptamer group's technology to improve the advanced drug delivery vehicles named after Aptamer Drug Conjugates (ApDCs).