As per our research report, the global antibody market size was valued at USD 145.7 Billion in 2022 and is estimated to grow USD 248.9 Billion by the end of 2027. The market is growing at a CAGR of 11.31% during the forecast period.
Antibodies are proteins that are produced in response to specific antigens by plasma cells. They are also called immunoglobulin. These antibodies are used as diagnostics as well as Therapeutic purposes for several indications of diseases, including but not limited to rheumatoid arthritis, non-Hodgkin lymphoma, psoriasis, Crohn’s disease, macular degeneration, hypercholesterolemia, and asthma. Owing to several product launches, the antibodies market is projected to witness steady growth. Effective harmonization of product development, approval, and registration guidelines in some of the major markets, such as the United States and the European Union, can speed up the research and development of antibody-related products.
MARKET DRIVERS
A key factor driving the market growth during the forecast period is the increasing demand for therapeutic antibodies, including monoclonal and polyclonal antibodies. Antibodies are also the dominant biopharmaceuticals targeting the abnormal cells specifically. Therefore, many pharmaceutical and biotechnology companies have started to focus on developing advanced antibodies to treat chronic diseases like cancer, rheumatic heart disease, and arthritis.
In managing healthcare costs, high drug costs, particularly biologics, are becoming an increasingly important issue. With increasing spending on health care, the economic burden of cancer and other chronic diseases is growing. Improvements in the production of therapeutic antibodies have reduced the cost of manufacturing, and therefore, the penetration of antibodies has increased in cost-sensitive markets.
Another major factor driving the growth of the antibody market is the patent expiry of several successful monoclonal antibodies shortly. In a couple of years, most antibodies like Avastin, Herceptin, and Mabthera will lose their patents. For example, Herceptin's license (trastuzumab) expired in July 2014 in Europe and will expire in June 2019 in the United States. Many firms, including Amgen Inc., Synthon, Biocon, and Pfizer Inc., are developing trastuzumab biosimilar, which is expected to boost demand for products producing antibodies.
MARKET RESTRAINTS:
Variations in the antibody techniques have resulted in inadequate reproductive results. No standards for their validation reproducibility across every antibody offering. The variations in the antibodies affect the results of research and clinical screening tests. The development process of monoclonal antibodies is a time-consuming and complicated procedure. One of the main concerns is that technologies require large bioreactors and filtration systems for antibody production, which is expected to impede global antibody market growth.
Impact of COVID-19 on the global antibodies market:
In March 2020, the world health organization announced COVID-19 as the pandemic. The emergence of COVID-19 has positively impacted the antibody market growth during the COVID-19 period. It has boosted the research activities due to the efforts made to understand the dynamics of infection. According to recent reports, most research and reagent manufacturing with personalized medicine will have a better share in the coming years. This is because many companies have mounted their operations for testing and identifying coronavirus. The latest technologies of genetic and molecular testing have been used to test the COVID-19.
REPORT COVERAGE:
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REPORT METRIC |
DETAILS |
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Market Size Available |
2021 to 2027 |
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Base Year |
2021 |
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Forecast Period |
2022 to 2027 |
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Segments Analysed |
By Product Type, Indication, End User, Application, and Region |
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Various Analyses Covered |
Global, Regional & Country Level Analysis, Segment-Level Analysis, Drivers, Restraints, Opportunities Challenges, PESTLE Analysis, Porter’s Five Forces Analysis, Competitive Landscape, Analyst Overview on Investment Opportunities |
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Regions Analysed |
North America, Europe, Asia Pacific, Latin America, Middle East, and Africa |
This research report on the global antibodies market has been segmented based on the product type, indication, end-user, application, and region.
Antibodies Market - By Product Type:
Based on Product Type, the Monoclonal antibodies segment to dominate the global antibodies market during the forecast period. The monoclonal antibodies are laboratory-made proteins that boost the immune system to fight against harmful pathogens such as a virus. The monoclonal market is anticipated to hold the largest market share in the coming years.
Antibodies Market - By Indication:
Based on the indication, the cancer segment is forecasted to account for the leading share during the forecast period. Over the years the cancer diseases have been increasing due to the uncontrollable growth of abnormal cells in the body. This factor is propelling the cancer indication segment to the extent. The autoimmune diseases segment is anticipated to rule the growth rate of the market in the coming years.
Antibodies Market - By End User:
Based on End User, the Cancer indication type segment is predicted to account highest market share over the forecast period due to the broad range of applications of monoclonal antibodies for the treatment of various cancers. Prevalence of cancer disease, rising number of research activities on antibodies, and improving healthcare infrastructure facilities drive the growth of these segments.
Antibodies Market – By Application:
Based on Application, the medical and experimental segments are expected to have the majority share in the market as an increase in the research and development activities on antibodies' production. The rising demand for antibodies in the global market is more likely to encourage the growth of these segments.
Antibodies Market – By Region:
In the last few years, North America was the market's largest revenue-generating area. Due to the presence of many other leading biopharmaceutical and biotechnology firms in this market, this region is expected to maintain its role during the forecast period. Increasing focus on biomedical, stem cell, and cancer research is the primary factor influencing the North American Antibodies market growth. Like cardiovascular and blood diseases, the rising prevalence of chronic diseases is expected to drive market growth during the forecast period. American cancer society estimates 1,735,350 people have been diagnosed with chronic diseases in the recent period. The rising number of biotechnology and biopharmaceutical companies are adopting advanced research antibodies and products to examine the stem cells are more likely to accelerate the market.
The European antibodies market held a substantial share in the global antibodies market during the forecast period, and it is projected to register promising CAGR during the forecast period. It is owing to the growing prevalence of cardiovascular diseases and blood diseases. Increasing demand for antibodies for research reproductivity and R&D expenditure and funding expected to witness a steady rise in the coming years.
The Asia pacific antibodies market is expected to be the fastest-growing regional market and was one of the largest market shareholding regions in 2019 with an increasing CAGR of research antibodies and reagents market during the previous year. Moreover, improving healthcare infrastructure, lowering regulatory hurdles, and increasing pharmaceuticals investments are projected to augment market growth.
The Latin American antibodies market is estimated to hike at a steady rate between 2020 to 2025. Government investments in improving healthcare infrastructure are projected to drive market growth over the forecast period.
The Middle East Africa Antibodies market had accounted for a smaller share in the global market but was estimated to register a healthy CAGR during the forecast period. Substantial increase in the research and development activities to develop effective diagnostic therapy and an increasing number of research activities are projected to propel the market growth of antibodies market in this region.
KEY MARKET PARTICIPANTS:
Notable companies leading the global antibodies market profiled in the report are Abbott Diagnostics, Novartis AG, Pfizer Inc., Thermo Fisher Scientific Inc., Eli Lilly and company, A.G. Scientific, Inc., Bristol-Myers Squibb, AbbVie Inc., and F. Hoffmann-La Roche Ltd.
RECENT MARKET DEVELOPMENTS:
In April 2016, the U.S. approved ERELZI-Novartis biosimilar to Enbrel. The European Union subsequently approved ERELZI in April 2017. Novartis opened the enormous market opportunity for RA in 28 EU member states with this authorization.
1.Introduction
1.1 Market Definition
1.2 Study Deliverables
1.3 Base Currency, Base Year and Forecast Periods
1.4 General Study Assumptions
2. Research Methodology
2.1 Introduction
2.2 Research Phases
2.2.1 Secondary Research
2.2.2 Primary Research
2.2.3 Econometric Modelling
2.2.4 Expert Validation
2.3 Analysis Design
2.4 Study Timeline
3. Overview
3.1 Executive Summary
3.2 Key Inferences
4. Drivers, Restraints, Opportunities, and Challenges Analysis (DROC)
4.1 Market Drivers
4.2 Market Restraints
4.3 Key Challenges
4.4 Current Opportunities in the Market
5. Market Segmentation
5.1 By Product Type
5.1.1 Monoclonal Antibodies
5.1.1.1 Murine
5.1.1.2 Chimeric
5.1.1.3 Humanized
5.1.1.4 Human
5.1.2 Polyclonal Antibodies
5.1.2.1 Type I
5.1.2.2 Type II
5.1.2.3 Type III
5.1.2.4 Type IV
5.1.2.5 Type V
5.1.2.6 Type VI
5.1.2.7 Type VII
5.1.2.8 Type VIII
5.1.3 Antibody-Drug Complexes
5.1.3.1 Immunogen Technology
5.1.3.2 Seattle Genetics Technology
5.1.3.3 Immunomedics Technology
5.2 By Indication
5.2.1 Cancer
5.2.2 Autoimmune Diseases
5.2.3 Infectious Diseases
5.2.4 Cardiovascular Diseases
5.2.5 CNS Disorders
5.2.6 Others (Inflammatory, Microbial Diseases, & Other)
5.3 End User
5.3.1 Hospitals/Clinics
5.3.2 Research Institute
5.3.3 Diagnostic Laboratories
5.4 Application
5.4.1 Medical
5.4.2 Experimental
5.4.2.1 Western Blot
5.4.2.2 ELISA
5.4.2.3 Radioimmune Assays
5.4.2.4 Immunofluorescence
5.4.2.5 Other (Immunohistochemistry, Immunoprecipitation, & Immunocytochemistry)
6. Geographical Analysis
6.1 North America
6.1.1 Introduction
6.1.2 United States
6.1.3 Canada
6.2 Europe
6.2.1 Introduction
6.2.2 U.K
6.2.3 Spain
6.2.4 Germany
6.2.5 Italy
6.2.6 France
6.3 Asia-Pacific
6.3.1 Introduction
6.3.2 China
6.3.3 India
6.3.4 Japan
6.3.5 South Korea
6.3.6 Australia
6.4 Latin America
6.4.1 Introduction
6.4.2 Brazil
6.4.3 Argentina
6.4.4 Mexico
6.5 Middle East & Africa
6.5.1 Introduction
6.5.2 Middle-East
6.5.3 Africa
7. Pipeline Product Analysis
7.1 Overview
7.2 Pipeline Development Landscape
7.3 Molecular Targets in the Pipeline
7.4 Clinical Trials
7.4.1 Clinical Trial Duration by Stage of Development, Indication, Molecule Type and Molecular Target
7.4.2 Clinical Trial Size by Stage of Development, Indication, Molecule Type and Molecular Target
7.5 Key Trends in Antibodies Development
7.5.1 Targeted Therapies
7.6 Promising Antibodies in Pipeline
7.7 Heat Map of Safety and Efficacy for Pipeline and Marketed Antibodies
8.Strategic Analysis
8.1 PESTLE analysis
8.1.1 Political
8.1.2 Economic
8.1.3 Social
8.1.4 Technological
8.1.5 Legal
8.1.6 Environmental
8.2 Porter’s Five analysis
8.2.1 Bargaining Power of Suppliers
8.2.2 Bargaining Power of Consumers
8.2.3 Threat of New Entrants
8.2.4 Threat of Substitute Products and Services
8.2.5 Competitive Rivalry within the Industry
9.Market Leaders' Analysis
9.1 Abbott Diagnostics (U.S.)
9.1.1 Overview
9.1.2 Product Analysis
9.1.3 Financial analysis
9.1.4 Recent Developments
9.1.5 SWOT analysis
9.1.6 Analyst View
9.2 Novartis AG (Switzerland)
9.3 Pfizer Inc. (U.S.)
9.4 Thermo Fisher Scientific Inc. (U.S.)
9.5 Eli Lilly and Company (U.S.)
9.6 A.G. Scientific, Inc. (U.S.)
9.7 Bristol-Myers Squibb (U.S.)
9.9 F. Hoffmann-La Roche Ltd. (Switzerland)
9.10 AbbVie Inc. (U.S.)
10.Competitive Landscape
10.1 Market share analysis
10.2 Merger and Acquisition Analysis
10.3 Agreements, collaborations and Joint Ventures
10.4 New Product Launches
11.Expert Opinions
11.1 Market Outlook
11.2 Investment Opportunities
Appendix
a) List of Tables
b) List of Figures
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