Global Flash Chromatography Market Size, Share, Trends, COVID-19 Impact & Growth Analysis Report – Segmented By Technique Type (Size Exclusion, Chiral Separation, Reverse Phase, Ion Exchange), End-User (Pharmaceuticals & Biotechnology Industries, Contract Research Organizations, Others), and Region (North America, Europe, APAC, Latin America, Middle East and Africa) – Industry Forecast from 2024 to 2029

Updated On: January, 2024
ID: 13252
Pages: 190

Global Flash Chromatography Market Size (2023 to 2028)

The global flash chromatography market is expected to grow to USD 396.9 million by 2028 from USD 307.7 million in 2023, growing at a CAGR of 5.22% from 2023 to 2028.

Flash chromatography is a purification technique that uses air pressure and produces a rapid separation of smaller silica gel particles. A gas pressure of 50–200 psi distinguishes it from conventional column techniques. With silica gel particle sizes between 40 and 60 mm, flash chromatography columns are commonly pre-packaged plastic cartridges. A gradient pump, injection ports, a UV detector, and a fraction collector to collect the eluent are among the components of automated flash chromatography systems that are typically found on HPLC systems. Flash chromatography as a purification technique is gaining worldwide recognition and demand in recent times and is expected to continue growing during the forecast period.

The market for flash chromatography deals with the products and services of flash chromatography for different end-users and procedures. It provides the companies which require the technique with appropriate devices and technology. Aside from production, the research and development area of the market is also a prevalent segment. 

Impact of COVID-19 on the global flash chromatography market:

The flash chromatography market is expected to increase during the COVID-19 pandemic. Researchers are using chromatography, a sophisticated laboratory-based analytical technique, to understand the Sars-CoV-2 virus better, and create innovative vaccinations and test equipment to help in the fight against the COVID-19 pandemic. Following the COVID-19 pandemic, the increasing use of flash chromatography systems in pharmaceutical R&D is anticipated to promote market expansion. Users continue to favor flash devices with complex detectors like single quad mass spectrometers and evaporative light scattering detectors (ELSD) (SQMS). The chromatography stage is one of the most crucial purification steps for separating the vaccine from the rest of the combination. Another essential step in producing vaccines is purifying and filtering the vaccines at various locations. Therefore, one of the most required purifying methods involves using chromatography columns to separate the immunization from the rest of the combination. In the forecast period, some of the biggest drivers of the flash chromatography market include advances in chromatography technology, such as increased automation in chromatography tools, the rising demand for purification and filtration by biotech companies, and developing federal investment opportunities in the biotechnology and pharmaceutical industries.


The low-pressure technique called flash chromatography is frequently used in pharmaceutical laboratories to synthesize chemical compounds, drug discovery, DNA purification, and R&D. The market is being driven ahead by technological advancements in flash chromatography systems as an increase in research-based activities globally. The technique of flash chromatography is used to separate and purify the desired component from a mixture. The need for flash chromatography for drug development will soar due to increased research and development efforts by pharmaceutical and biotechnology companies, driving the flash chromatography market forward.

Growing equipment and demand have fuelled the growth of the global flash chromatography market.

The rise in chromatography equipment automation has dramatically impacted the market's expansion. In addition, the biotech and pharmaceutical industries' growing need for filtration and purification has also driven growth in the flash chromatography sector. Worldwide, governments are also making significant investments in biotech and pharmaceutical companies. Furthermore, expanding uses of flash chromatography in several sectors, including forensic science, life science, and food & beverage, are further fuelling the expansion of the flash chromatography market. Additionally, partnerships between research labs and flash chromatography producers will fuel the market's development during the projected period.


Lack of awareness and skilled professionals hinders the growth of the flash chromatography market.

The flash chromatography industry is rapidly running out of competent workers. To operate flash chromatography equipment correctly, one needs expertise in various chromatography techniques and relevant experience. However, a lack of knowledge and study of chromatography is anticipated to restrict the market growth.




Market Size Available

2022 to 2028

Base Year


Forecast Period

2023 to 2028

Segments Analysed

By Technique Type, End-User & Region.

Various Analyses Covered

Global, Regional & Country Level Analysis, Segment-Level Analysis, DROC, PESTLE Analysis, Porter’s Five Forces Analysis, Competitive Landscape, Analyst Overview of Investment Opportunities

Regions Analysed

North America, Europe, Asia Pacific, Latin America, the Middle East, and Africa


This research report on the global flash chromatography market has been segmented and sub-segmented into the following categories.

Global Flash Chromatography Market - By Technique Type:

  • Size Exclusion
  • Chiral Separation
  • Reverse Phase
  • Ion Exchange

Due to the pharmaceutical and biotech industries' continuous use of reverse-phase chromatography for protein purification and drug development, the reverse-phase category held the biggest market share in 2020. In addition, significant development drivers for the market will also come from the growing use of aqueous solutions for sample preparation by key nations around the globe.

Global Flash Chromatography Market - By End-User:

  • Pharmaceuticals & Biotechnology Industries
  • Contract Research Organizations
  • Others

Due to their ongoing R&D efforts and production activities, which rely heavily on flash chromatography systems, the pharmaceutical and biotechnology segment held the highest share in 2022.

Global Flash Chromatography Market - By Region:

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East and Africa

Geographically, North America is anticipated to witness a significant share of the global market during the forecast period. The regional market growth is fuelled by the presence of key market players and the advanced healthcare infrastructure. In addition, growing pharmaceutical industry research efforts and chromatography technology improvements further boost the market growth. Furthermore, emerging markets such as the United States and Canadian markets are contributing to the North American regional market growth. 

Europe is anticipated to occupy a sizable share of the global flash chromatography market. Favorable government healthcare policies and rising demand for flash chromatography in the biopharmaceutical & biotechnology industry, food industry, and forensic pathology across the region. Additionally, increasing pharmaceutical R&D expenditures are expected to boost market expansion. For example, consider the Horizon 2020 financing program for science R&D and innovation, which was formed by the European Union and granted approximately USD 90 billion in funding from 2014 to 2020.

The Asia Pacific is projected to grow faster during the forecast period due to rising healthcare infrastructure investment and an increase in contract research & manufacturing firms. Additionally, the market expansion is aided by the efforts of key international players to extend their operations in the Asia-Pacific region. Emerging markets such as China, Japan, and India are helping the APAC regional market expansion. China accounted for the largest share of the market during the forecast period.


There are several companies and industries in the global flash chromatography market. Here are some key players, VMR, Buchi Corp., Teledyne ISCO, Biotage AB, Shimadzu Corporation, GE Healthcare, Interim SA, Tosoh Corporation, Agilent Technologies, PerkinElmer Inc., Thermo Fisher Scientific Inc., Gilson, Waters Corporation, W R Grace and Company, etc.


  • On May 30, 2022, a new flash purification platform called the Biotage Selekt Enkel was released from Biotage. The Biotage Enkel is a devoted purification workhorse with a modular architecture that enables application customization. Additionally, it uses the Biotage Selekt family's low-solvent consumption process for more environmentally friendly operation and sustainability.
  • The new Biotage Selekt Enkel is a dependable and sturdy instrument designed to execute routine purifications in the drug discovery workflow with a decreased environmental effect.
  • On June 10, 2021, reverse phase (C18AQ) flash chromatography cartridges were used in sample desalting. a C18AQ cartridge is utilized to purify the sample using a step gradient for the flash chromatography to confirm that the salt impurities with an MW are very closely targeted and removed using pure water, thus ensuring desalting. 

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Frequently Asked Questions

Which region accounted for the largest share of the global flash chromatography market in 2021?

The North American region accounted for more than 40% of the global market share in 2021. 

Which region has the fastest CAGR in the global flash chromatography market by 2027?

Geographically, the APAC regional market is estimated to register the fastest CAGR of 7.13% from 2022 to 2027.

Based on technique, which was the largest segment in 2021?

Based on technique, the reverse phase segment led the market accounting for more than 35% of the global market share in 2021.

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