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Global HPLC (High-Performance Liquid Chromatography) Market Size, Share, Trends and Growth Analysis Report – Segmented By Product (Instruments, Consumables and Accessories), Application (Clinical Research, Diagnostics and Forensics) and Region - Industry Forecast from 2023 to 2028

Published: March, 2023
ID: 7736
Pages: 175
Formats: report pdf report excel report power bi report ppt

Global HPLC Market Size (2023 to 2028)

The global market size for high-performance liquid chromatography is expected at around USD 4.02 Billion in 2023 and is expected to grow at a CAGR of 5.7% to reach USD 5.31 Billion by 2028.

Global HPLC Market Share Insights:

  • Based on product, the instruments segment led the market and captured 42.5% of the global HPLC market share in 2022.
  • Based on application, the clinical research segment dominated the market and held 36.4% of the global market share in 2022.
  • North America had the biggest worldwide market share in 2022, which was 31.7%. 
  • The European region accounted for a notable share of the global market in 2022. 

High-Performance Liquid Chromatography (HPLC) is a method in analytical chemistry. The HPLC is used to separate, identify, and measure the quality of each component in a mixture. The HPLC is a multipurpose method used in the clinical diagnosis of diseases & disorders and in the food industry for quality control. Furthermore, HPLC can be used for analysis in pharmaceutical labs and scientific research. Moreover, HPLC is an expensive and sophisticated technique. Therefore, HPLC was mostly preferred over other chromatography techniques like gas chromatography because of its reliability and accuracy. In contrast, standard liquid chromatography relies on gravity to pass the mobile phase through the column.


HPLC is a high-sensitivity technique and offers greater accuracy, due to which the adoption is growing significantly and resulting in the HPLC market growth.

In addition, high-performance liquid chromatography's ability to identify the drug, monitor diseases, and adopt hyphenated techniques further accelerates the market's growth rate. Moreover, an increase in R&D investments is fuelling the HPLC market. Furthermore, the rise in global contract research organizers and pharmaceutical industries may propel market growth. Furthermore, the rise in the economy of the countries like China and India may boost the market in the coming years. 

The manufacturers mainly concentrate on new technologies to help researchers get high-quality analysis, a significant opportunity for the growth of High-Performance Liquid Chromatography. Moreover, increasing demand for the HPLC technique will boost the market.


The major restrain of the HPLC industry is the high cost of HPLC systems. The lack of highly professional laborers may hinder market growth. The supplier and the buyer's bargaining power may affect the market growth. The strict rules by the governments are another significant factor restraining the market. The rise in the competition for new techniques will challenge the HPLC market in the coming years. The lack of awareness about HPLC techniques in some emerging countries may be a drawback for the market.

Impact of COVID-19 on the global HPLC Market:

COVID-19 was well known as the coronavirus globally. The WHO announced COVID-19 as a pandemic in March 2020. More than 200 countries have announced a strict lockdown guideline to curb the spread of the novel coronavirus disease. Due to the lockdown, all companies got shut down and saw huge losses during the pandemic. The High-Performance Liquid Chromatography market has faced many difficulties sustaining its growth. The break of the supply chain is the major drawback for the market. The insufficient funding to research and academic institutes and low demand for the product hinder the market. But a few key players in the market are trying their best to be in the market, such as Agilent Technologies, with established business continuity plans (BCPs) trying their best to secure that their production does not fall behind.




Market Size Available

2022 to 2028

Base Year


Forecast Period

2023 to 2028

Segments Covered

By-Products, Instruments, Consumables, Applications, and Region

Various Analyses Covered

Global, Regional & Country Level Analysis, Segment-Level Analysis, Drivers, Restraints, Opportunities, Challenges; PESTLE Analysis; Porter’s Five Forces Analysis, Competitive Landscape, Analyst Overview of Investment Opportunities

Regions Covered

North America, Europe, Asia Pacific, Latin America, the Middle East, and Africa


This research report on the global high-performance liquid chromatography market has been segmented and sub-segmented based on the products, instruments, consumables, applications, and region.

HPLC Market - By Product:

  • Instruments
  • Consumables
  • Accessories

Based on the product, the HPLC Instruments segment had the largest share in the global HPLC market in 2022. The growing usage of HPLC equipment primarily drives the growth of the instruments segment to analyze various sectors and growing R&D activities from the pharmaceutical, biotech, food, and agriculture industries. As a result, the consumable market is expected to rise at the highest CAGR during the forecast period. In addition, the growing investments in the healthcare sector are favoring the segment’s growth.

HPLC Market - By Application:

  • Clinical Research
  • Diagnostics
  • Forensics

Based on the application, the clinical research segment was estimated to grow with a higher CAGR during the forecast period. It is used to know inorganic impurities such as plant or animal proteins in bulk pharmaceutical materials, excipients, or catalysts. Therefore, the increase in investments in this segment boosts the HPLC clinical research market.

HPLC Market - By Region:

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • The Middle East and Africa

The North America HPLC market holds a significant market share in the global market owing to the presence of major players. North America holds a significant market share during the forecast period. The United States and Canada are the most significant contributors to the North American market. The increase in R&D investments in the US is the primary reason for the market growth. The booming pharmaceutical industry in Canada is feeling the market. The US Food and Drug Administration's recommendations on chromatographic techniques to ensure proper identity, purity, and concentration of pharmaceuticals increase the use of high-performance liquid chromatography techniques. The government's policies and funding are boosting the market growth.

The European HPLC market is predicted to account for the second-largest global market share during the forecast period. The increased investments by major players in the pharmaceutical and biotechnology industry are propelling the market. The growing demand for the LC-MS technique and increased R&D investments are boosting the market. Moreover, the major contributor to the European market was the United Kingdom, Germany, and Russia. The rise in awareness of HPLC techniques and government policies affects the market.

The HPLC market in Asia-pacific is expected to witness a significant growth rate due to numerous companies in this region. Asia-pacific is expected to witness a significant growth rate during the forecast period. Increasing interest in research activities in developing countries like China, India, and Japan will boost market expansion. In addition, the rise in awareness about HPLC techniques propels the market. The easy government policies and the low maintenance cost are grabbing the investor's attention, which will lead to an increase in the HPLC market in the Asia Pacific in upcoming years.

The Latin America HPLC market is anticipated to grow steadily during the forecast period. The presence of emerging economies and the growing R&D efforts by the market participants are driving the regional market growth.

The HPLC market in MEA is projected to grow at a moderate CAGR during the forecast period.


A few of the noteworthy leading the global high-performance liquid chromatography market profiled in this report are Waters Corporation, Agilent Technologies, Shimadzu Corporation, Thermo Fisher Scientific Inc., GE Healthcare, PerkinElmer Inc., Bio-Rad Laboratories Inc., Gilson Inc., Phenomenex Inc., and JASCO Inc.

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How much was the global HPLC market worth in 2021?

The global high-performance liquid chromatography market size was worth USD 3.6 billion in 2021.

What is the projected market value of HPLC market by 2027?

The global HPLC market is anticipated to be worth USD 5.02 billion by 2027.

Which segment by product held the major share of the global HPLC market in 2021?

Based on product, the instruments segment captured the most significant share of the global HPLC market in 2021.

Who are the promising players in the HPLC market?

Waters Corporation, Agilent Technologies, Shimadzu Corporation, Thermo Fisher Scientific Inc., GE Healthcare, PerkinElmer Inc., Bio-Rad Laboratories Inc., Gilson Inc., Phenomenex Inc., and JASCO Inc. are a few of the companies playing a notable role in the HPLC market.

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