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Global High-Resolution Melting Analysis Market Size, Share, Trends, COVID-19 Impact & Growth Analysis Report – Segmented By Product And Service, Application, End-User & Region - Industry Forecast (2022 to 2027)

Published: January, 2022
ID: 2727
Pages: 170
Formats: report pdf report excel report power bi report ppt

Global High-Resolution Melting Analysis Market Size (2022 to 2027)

The size of the global high-resolution melting analysis market is predicted to be worth USD 287.88 million in 2022 and USD 343.57 million by 2027, growing at a CAGR of 3.6% during the forecast period

The high-resolution melting analysis is a powerful and robust methodology in molecular biology to detect epigenetic differences, polymorphisms, and mutations in double-stranded DNA samples. It was first discovered and developed by Idaho Technology and the University of Utah. High-resolution melting analysis has several advantages over genotyping technologies, such as cost-effectiveness, it is robust and rapid compared to genotyping technologies, and it is relatively straightforward.


Increasing investment in R&D, increasing applications of this technology in epigenetics, and digitizing mutations are significantly driving the growth of the global high-resolution melting analysis market.

Benefits such as no probe use, closed tube system, prevention of post-PCR sample contamination, and high precision of melting profile analysis further drive the growth of the HRM analysis market.

The global high-resolution melting analysis market is likely to have a successful future due to the ongoing research and development in this field sponsored by several prominent companies operating in this particular field. For example, the United States FDA approves many treatments designed to meet a specific genomic profile or the genetic makeup of the patient's tumor.

Additionally, factors such as the increasing prevalence of chronic diseases, increasing demand for personalized medicine, and supportive government initiatives are expected to impact the HRM testing market positively. Personalized medicine, also known as precision medicine, is a powerful and innovative approach to preventing and treating disease after considering the differences in different genetic combinations, lifestyle, and environmental factors. Recent developments in next-generation sequencing (NGS), genomics, and big data analysis have contributed to the strengthening of the precision medicine approach. TheIn addition, the FDA has previously addressed several treatment options designed to meet the requirements of a specific genetic makeup or genomic profile of a patient's tumor. It, in turn, is expected to drive demand for HRM analysis over the forecast period.

Opportunities for growth in biotechnology research, well-established reimbursement policies, increased government investment in academic institutions. And a favorable regulatory environment is a key factor in the development of the academic research segment. Besides, according to the OECD, there has been a significant increase in the number of patents granted in biotechnology due to intellectual property importance. The development in molecular biology, biotechnology, and medicine is expected to increase the demand for human resource management products in the academic research segment.


A technical limitation associated with HRM-QPCR analysis is hampering the market growth. Problems related to data storage are limiting the market growth. Reducing Cost of Other Genotyping Technologies Hinder Market Growth

The expected reduction in other genotyping technologies is a significant challenge to the global HRM analysis market. In addition, the security concerns associated with the storage of data are another major challenge.

Impact of COVID-19 on the global high-resolution melting analysis market

Since the COVID-19 virus outbreak in December 2019, the disease has spread to more than 180 countries worldwide, and the World Health Organization has declared it a public health emergency. The global impacts of the 2019 coronavirus disease (COVID-19) are already starting to be felt and will significantly affect the high-resolution melting analysis market in 2020. The COVID-19 outbreak has had effects in many aspects, such as flight cancellations; travel bans and quarantines; restaurants closed; all restricted interior events; declared an emergency in many countries; a massive downturn in the supply chain; the unpredictability of the stock market; declining business security, growing public panic, and uncertainty about the future. COVID-19 can influence the global economy in three ways, directly influencing production and demand, creating supply chain and market interference, and its financial impact on businesses and financial markets.




Market Size Available

2021 to 2027

Base Year


Forecast Period

2022 to 2027

Segments Covered

By-Products and Services, Application, End-User and Region

Various Analyses Covered

Global, Regional & Country Level Analysis, Segment-Level Analysis, DROC, PESTLE Analysis, Porter’s Five Forces Analysis, Competitive Landscape, Analyst Overview on Investment Opportunities

Regions Covered

North America, Europe, APAC, Latin America, Middle East & Africa


This research report on the global high-resolution melting analysis market has been segmented based on Product and Service, Application, End User, and geography.

High-Resolution Melting Analysis Market - By Product and Service:

  • Reagents and Consumables
    • Specialized PCR Reagents
    • Intercalating Dyes
  • Instruments
  • Software and Services

The HRM reagents and consumables exist as one of the high potential product segments of the HRM analysis market based on the products and services. Factors like cost-effectiveness and growing demand for research about cancer, HIV, and other genetic disorders. Amplifying investments from public and private organizations, funds, and approvals and having consciousness about personalized medicine concepts are leading the market growth rate.

High-Resolution Melting Analysis Market - By Application:

  • SNP Genotyping
  • Mutation Discovery
  • Species Identification
  • Pathogen Identification
  • Epigenetics
  • Other Applications

Based on application, the SNP genotyping segment holds the largest share in the high-resolution melting analysis market based on the application analysis. The segment growth is due to intensifying investments for research and developments, increasing infectious diseases, genetic disorders, and other chronic diseases. The massive number of genotyping-based research and development activities drives the high-resolution melting analysis market during the assessment period.

High-Resolution Melting Analysis Market - By End User:

  • Research Laboratories and Academic Institutes
  • Pharmaceutical and Biotechnology Companies
  • Hospitals and Diagnostic Centres
  • Other End Users

Based on the end-user, the research laboratories and academic institutes segment hold the highest share in the high-resolution melting analysis market based on end-user analysis. This part's growth is due to increasing demand for simple and effective molecular diagnostics, advancements in technology from the genotyping by utilizing labeled probes for HRM. Growing demand for quick and powerful genotype analysis of higher samples for enormous scale genotyping impacts the segment growth.

High-Resolution Melting Analysis Market - By Region:

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • The Middle East and Africa

North America accounted for the largest market share of 45.6% in 2019. The key factors attributing its high revenue share are the increased investments in research and development, high-quality healthcare infrastructure, and the availability of better reimbursement and health care options.

Europe comes in second in terms of market share owing to the rising awareness and establishment of HRM procedures.

However, Asia-Pacific is estimated to grow at the highest CAGR during the forecast period because of exponentially greater population numbers. The Asia-Pacific region is predicted to be the fastest-growing industry during the forecast period. The main factors contributing to this are strong population growth, an increasing number of cancers, and other chronic diseases, which lead to significant unmet medical needs.


The significant players in the global high-resolution melting analysis market include Thermo Fisher Scientific Inc. (U.S.), F. Hofmann-La Roche Ltd. (Switzerland), Bio-Rad Laboratories (U.S.), and QIAGEN N.V. (Netherlands). Other players in the market include Agilent Technologies Inc. (U.S.), bioMérieux S.A. (France), Illumina, Inc. (U.S.), Meridian Bioscience, Inc. (U.S.), Novacyt (France), Azura Genomics (U.S.), Canon Biomedical (U.S.), and PREMIER Biosoft (U.S.),


  • On October 8, 2020, Bio-Rad Laboratories, Inc. announced the global launch of its CFX Opus 96 and CFX Opus 384 real-time PCR systems as well as, a platform for analysis, data management, and cloud-based instrument connectivity.
  • On September 26, 2020, PREMIER Biosoft today announced the release of GlycanExplorer ™ software version 1.0. This software was designed in alliance with Thermo Fisher Scientific for the characterization of biotherapeutic glucans. 
  • On September 14, 2020, Meridian Bioscience, Inc., a significant supplier of diagnostic test solutions and critical raw materials for the life sciences, is gratified to announce the launch of a new pair of anti -SARS-CoV-2. Highly sensitive to trimeric spike protein to promote the improvement of COVID-19 tests from patient saliva.

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