Global High-Resolution Melting Analysis Market Size, Share, Trends, COVID-19 Impact & Growth Analysis Report – Segmented By Product and Service (Reagents and Consumables, Instruments, Software and Services), Application (SNP Genotyping, Mutation Discovery, Species Identification, Pathogen Identification, Epigenetics and Other Applications), End-User & Region - Industry Forecast from 2024 to 2029

Published: January, 2024
ID: 2727
Pages: 170

Global High-Resolution Melting Analysis Market Size (2023 to 2028)

The size of the global high-resolution melting analysis market is predicted to be worth USD 298.2 million in 2023 and USD 355.9 million by 2028, growing at a CAGR of 3.6% during the forecast period. 

MARKET DRIVERS:

The growing demand for precision medicine primarily drives the growth of the HRM analysis market. Precision medicine is a powerful and innovative approach to preventing and treating disease after considering the differences in genetic combinations, lifestyle, and environmental factors. Recent developments in next-generation sequencing (NGS), genomics, and extensive data analysis have strengthened the precision medicine approach. The growing investments to conduct R&D activities further fuels the growth rate of the HRM analysis market. The global high-resolution melting analysis market is likely to have a promising future due to the ongoing research and development sponsored by several prominent companies in this field. For instance, the United States FDA approves many treatments designed to meet a specific genomic profile or the genetic makeup of the patient's tumor.

Factors such as the rising prevalence of chronic diseases and favorable government initiatives fuel the growth rate of the HRM analysis market. Benefits such as no probe use, closed tube system, prevention of post-PCR sample contamination, and high precision of melting profile analysis drive the growth of the HRM analysis market. The growing number of applications of HRM analysis such as epigenetics and digitizing mutations propel the growth of the global high-resolution melting analysis market.

The growing support from the regulatory bodies in favor of HRM analysis contributes to market growth. The FDA has previously addressed several treatment options designed to meet the requirements of a specific genetic makeup or genomic profile of a patient's tumor. It, in turn, is expected to drive demand for HRM analysis in the coming years. The growing efforts in biotechnology research, well-established reimbursement policies and increasing investments by the governmental organizations in academic institutions support the HRM analysis market growth.

MARKET RESTRAINTS:

The technical limitations associated with HRM-QPCR analysis are key factors that hamper the market growth. Problems related to data storage and reducing the cost of other genotyping technologies hinder market growth. The expected reduction in other genotyping technologies is a significant challenge to the global HRM analysis market. In addition, the security concerns associated with data storage are another major challenge.

Impact of COVID-19 on the global high-resolution melting analysis market

Since the COVID-19 virus outbreak in December 2019, the disease has spread to more than 180 countries worldwide, and the World Health Organization has declared it a public health emergency. The global impacts of the 2019 coronavirus disease (COVID-19) are already starting to be felt and will significantly affect the high-resolution melting analysis market in 2020. The COVID-19 outbreak has had effects in many aspects, such as flight cancellations; travel bans and quarantines; restaurants closed; restricted interior events; declared an emergency in many countries; a massive downturn in the supply chain; the unpredictability of the stock market; declining business security, growing public panic, and uncertainty about the future. COVID-19 can influence the global economy in three ways, directly influencing production and demand, creating supply chain and market interference, and its financial impact on businesses and financial markets. However, due to the reduced impact of COVID-19 and the growing adoption of new normalization, the high-resolution melting analysis market is anticipated to have a quick recovery and register a healthy growth rate during the forecast period.

REPORT COVERAGE:

REPORT METRIC

DETAILS

Market Size Available

2022 to 2028

Base Year

2022

Forecast Period

2023 to 2028

Segments Covered

By-Products and Services, Application, End-User, and Region

Various Analyses Covered

Global, Regional & Country Level Analysis, Segment-Level Analysis; DROC, PESTLE Analysis; Porter's Five Forces Analysis, Competitive Landscape, Analyst Overview of Investment Opportunities

Regions Covered

North America, Europe, APAC, Latin America, Middle East & Africa

 

This research report on the global high-resolution melting analysis market has been segmented based on Product and Service, Application, End User, and geography.

High-Resolution Melting Analysis Market - By Product and Service:

  • Reagents and Consumables
    • Specialized PCR Reagents
    • Intercalating Dyes
  • Instruments
  • Software and Services

Based on product and services, the reagents and consumables segment is anticipated to account for the major share of the global market during the forecast period owing to the rapid adoption of high-resolution melting analysis (HRMA) in various applications such as genotyping, DNA methylation analysis, and mutation scanning. The growing number of research activities in molecular biology, genetics, and personalized medicine further fuels the demand for reagents and consumables in HRMA and contributes to segmental growth. Factors such as cost-effectiveness, growing demand for research about cancer, HIV, and other genetic disorders and rising investments from public and private organizations, funds, and approvals further promote the growth rate of the reagents and consumables segment in the worldwide market.

The instruments segment is anticipated to account for a considerable share of the global market during the forecast period. The growing number of research and diagnostic laboratories where HRMA is widely utilized is one of the key factors propelling segmental growth. The integration of advanced features like real-time data analysis and user-friendly interfaces in instruments contributes to segmental growth. Continuous product innovations and investments in research and development by key market players further support the growth of the instruments segment in the high-resolution melting analysis market.

High-Resolution Melting Analysis Market - By Application:

  • SNP Genotyping
  • Mutation Discovery
  • Species Identification
  • Pathogen Identification
  • Epigenetics
  • Other Applications

Based on application, the SNP genotyping segment is predicted to capture the largest share in the high-resolution melting analysis market during the forecast period owing to the growing investments to conduct R&D activities, an increasing patient population suffering from infectious diseases, genetic disorders, and chronic diseases. The growing number of genotyping-based research and development activities is further boosting the growth rate of the SNP genotyping segment in the worldwide market. The growing research and development activities in genetics and genomics, rising demand for personalized medicine and pharmacogenomics, increasing need for accurate genotyping techniques and the growing number of advancements in high-throughput genotyping technologies drive the growth of the SNP genotyping segment.

The mutation discovery segment is expected to witness a healthy CAGR during the forecast period owing to the rising focus on understanding the genetic basis of diseases and identifying disease-causing mutations. The growing number of advancements in sequencing technologies and their integration with High-Resolution Melting Analysis, growing demand for precision medicine and targeted therapies, rising prevalence of genetic diseases and increasing need for efficient mutation detection methods.

High-Resolution Melting Analysis Market - By End User:

  • Research Laboratories and Academic Institutes
  • Pharmaceutical and Biotechnology Companies
  • Hospitals and Diagnostic Centres
  • Other End Users

Based on the end-user, the research laboratories and academic institutes segment captured a significant share of the global HRM analysis market in 2022. Factors such as growing demand for simple and effective molecular diagnostics and technological advancements from genotyping utilizing labeled probes for HRM promote the segment's growth. Growing demand for rapid and robust genotype analysis of higher samples for enormous-scale genotyping impacts segment growth. A favorable regulatory environment is a critical factor in the development of the academic research segment. Besides, according to the OECD, there has been a significant increase in the number of patents granted in biotechnology due to intellectual property importance. The development in molecular biology, biotechnology, and medicine is expected to increase the demand for human resource management products in the academic research segment.

High-Resolution Melting Analysis Market - By Region:

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • The Middle East and Africa

The high-resolution melting analysis market in North America accounted for the largest share of the global market in 2022 and the lead of the North American region is estimated to continue throughout the forecast period. Factors such as the presence of well-established healthcare infrastructure, technological advancements in genetic research and the high prevalence of genetic disorders primarily drive the North American market growth. A strong focus on personalized medicine and genomics research in the North American region further fuels the demand for high-resolution melting analysis technologies and contributes to the North American market growth. The growing number of initiatives from the North American governments to support genetic research and the presence of key market players in the region support the North American market growth.

The European HRM analysis market captured the second-largest share in the global market in 2022 and is predicted to register a healthy CAGR during the forecast period owing to the rising awareness and establishment of HRM procedures. The growing research and development activities in genetic analysis, favorable government policies supporting genomic research and rising awareness about genetic diseases fuel the growth of the European market. The presence of advanced healthcare systems, strong academic and research institutions and an increasing number of collaborations between academia and industry also contribute to market growth in Europe.

The HRM analysis market in Asia-Pacific is estimated to grow at the highest CAGR during the forecast period because of exponentially greater population numbers. Therefore, the Asia-Pacific region is predicted to be the fastest-growing industry during the forecast period. The rising focus on precision medicine, growing healthcare expenditure and growing investments in genetic research and development drive the HRM analysis market in APAC. The presence of a large population, high prevalence of genetic disorders and increasing awareness about personalized medicine drive the adoption of high-resolution melting analysis technologies and boost the APAC market growth. The growing number of advancements in healthcare infrastructure and an increasing number of research collaborations further contribute to market growth in the Asia Pacific.

The Latin American HRM analysis market is predicted to witness a steady CAGR during the forecast period owing to the growing number of improvements in the healthcare infrastructure, increasing government initiatives in genetic research and rising awareness about genetic diseases driving market growth in the Latin American region. The presence of a large patient population, expanding research capabilities, and growing adoption of advanced genomic technologies contribute to the growth rate of the Latin American market. Countries such as Brazil, Mexico, and Argentina are expected to have increased adoption of HRM analysis in the coming years, resulting in market expansion in this region.

The HRM analysis market in MEA is expected to register a moderate CAGR during the forecast period.

NOTABLE COMPANIES IN THIS MARKET:

The significant players in the global high-resolution melting analysis market include Thermo Fisher Scientific Inc. (U.S.), F. Hofmann-La Roche Ltd. (Switzerland), Bio-Rad Laboratories (U.S.), and QIAGEN N.V. (Netherlands). Other players in the market include Agilent Technologies Inc. (U.S.), bioMérieux S.A. (France), Illumina, Inc. (U.S.), Meridian Bioscience, Inc. (U.S.), Novacyt (France), Azura Genomics (U.S.), Canon Biomedical (U.S.), and PREMIER Biosoft (U.S.),

RECENT HAPPENINGS IN THIS MARKET:

  • In October 2020, Bio-Rad Laboratories, Inc. announced the global launch of its CFX Opus 96 and CFX Opus 384 real-time PCR systems, as well as BR.io, a platform for analysis, data management, and cloud-based instrument connectivity.
  • In September 2020, PREMIER Biosoft announced the release of GlycanExplorer ™ software version 1.0. This software was designed in alliance with Thermo Fisher Scientific to characterize biotherapeutic glucans. 
  • In September 2020, Meridian Bioscience, Inc., a significant supplier of diagnostic test solutions and critical raw materials for the life sciences, is gratified to announce the launch of a new pair of anti-SARS-CoV-2. Highly sensitive to trimeric spike protein to promote the improvement of COVID-19 tests from patient saliva.

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Frequently Asked Questions

What was the size of the high-resolution melting analysis market worldwide in 2021?

The global high-resolution melting analysis market size was valued at USD 278.8 million in 2021.

What is the growth rate of the global high-resolution melting analysis market?

The global high-resolution melting analysis market is anticipated to grow at a CAGR of 3.6% from 2022 to 2027.

Which segment by application held the promising share in the high-resolution melting analysis market?

Based on application, the SNP genotyping segment had the most significant share of the global market in 2021.

Who are the leading players in the high-resolution melting analysis market?

Thermo Fisher Scientific Inc. (U.S.), F. Hofmann-La Roche Ltd. (Switzerland), Bio-Rad Laboratories (U.S.), and QIAGEN N.V. (Netherlands). Other players in the market include Agilent Technologies Inc. (U.S.), bioMérieux S.A. (France), Illumina, Inc. (U.S.), Meridian Bioscience, Inc. (U.S.), Novacyt (France), Azura Genomics (U.S.), Canon Biomedical (U.S.), and PREMIER Biosoft (U.S.) are some of the notable companies in the high-resolution melting analysis market.

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