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Global High-Resolution Melting Analysis Market Size, Share, Trends, COVID-19 Impact & Growth Analysis Report – Segmented By Product and Service (Reagents and Consumables, Instruments, Software and Services), Application (SNP Genotyping, Mutation Discovery, Species Identification, Pathogen Identification, Epigenetics and Other Applications), End-User & Region - Industry Forecast from 2022 To 2027

Published: January, 2022
ID: 2727
Pages: 170
Formats: report pdf report excel report power bi report ppt

Global High-Resolution Melting Analysis Market Size (2022 to 2027)

The size of the global high-resolution melting analysis market is predicted to be worth USD 287.88 million in 2022 and USD 343.57 million by 2027, growing at a CAGR of 3.6% during the forecast period.

Global High-Resolution Melting Analysis Market Share Insights:

  • Based on product and service, the HRM reagents and consumables segment led the market in 2021.
  • Based on end-user, the research laboratories and academic institutes segment captured the most significant share of 72.6% of the global market in 2021.
  • Based on region, North America dominated the market and held 33% of the global market share in 2021.
  • The European region is estimated to be valued at USD 80.5 million by 2027.
  • The Asia-Pacific region is projected to grow at a CAGR of 5.2% from 2022 to 2027.

The high-resolution melting analysis is a powerful and robust methodology in molecular biology to detect epigenetic differences, polymorphisms, and mutations in double-stranded DNA samples. Idaho Technology and the University of Utah first discovered and developed it. High-resolution melting analysis has several advantages over genotyping technologies, such as cost-effectiveness, being robust, rapid compared to genotyping technologies, and relatively straightforward.

MARKET DRIVERS:

Increasing investment in R&D, increasing applications of this technology in epigenetics, and digitizing mutations propel the growth of the global high-resolution melting analysis market.

Benefits such as no probe use, closed tube system, prevention of post-PCR sample contamination, and high precision of melting profile analysis drive the growth of the HRM analysis market. Furthermore, the global high-resolution melting analysis market is likely to have a promising future due to the ongoing research and development sponsored by several prominent companies in this field. For instance, the United States FDA approves many treatments designed to meet a specific genomic profile or the genetic makeup of the patient's tumor.

In addition, factors such as the increasing prevalence of chronic diseases, increasing demand for personalized medicine, and supportive government initiatives are expected to positively impact the HRM testing market. Personalized medicine, also known as precision medicine, is a powerful and innovative approach to preventing and treating disease after considering the differences in genetic combinations, lifestyle, and environmental factors. Recent developments in next-generation sequencing (NGS), genomics, and extensive data analysis have strengthened the precision medicine approach. In addition, the FDA has previously addressed several treatment options designed to meet the requirements of a specific genetic makeup or genomic profile of a patient's tumor. It, in turn, is expected to drive demand for HRM analysis over the forecast period. Furthermore, growing efforts in biotechnology research, well-established reimbursement policies, and increased government investments in academic institutions are expected to reflect in the growth of the HRM market during the forecast period.

MARKET RESTRAINTS:

The technical limitations associated with HRM-QPCR analysis are key factors that hamper the market growth. Problems related to data storage and reducing the cost of other genotyping technologies hinder the market growth. The expected reduction in other genotyping technologies is a significant challenge to the global HRM analysis market. In addition, the security concerns associated with data storage are another major challenge.

Impact of COVID-19 on the global high-resolution melting analysis market

Since the COVID-19 virus outbreak in December 2019, the disease has spread to more than 180 countries worldwide, and the World Health Organization has declared it a public health emergency. The global impacts of the 2019 coronavirus disease (COVID-19) are already starting to be felt and will significantly affect the high-resolution melting analysis market in 2020. The COVID-19 outbreak has had effects in many aspects, such as flight cancellations; travel bans and quarantines; restaurants closed; restricted interior events; declared an emergency in many countries; a massive downturn in the supply chain; the unpredictability of the stock market; declining business security, growing public panic, and uncertainty about the future. COVID-19 can influence the global economy in three ways, directly influencing production and demand, creating supply chain and market interference, and its financial impact on businesses and financial markets. However, due to the reduced impact of COVID-19 and the growing adoption of new normalization, the high-resolution melting analysis market is anticipated to have a quick recovery and register a healthy growth rate during the forecast period.

REPORT COVERAGE:

REPORT METRIC

DETAILS

Market Size Available

2021 to 2027

Base Year

2021

Forecast Period

2022 to 2027

Segments Covered

By-Products and Services, Application, End-User, and Region

Various Analyses Covered

Global, Regional & Country Level Analysis, Segment-Level Analysis; DROC, PESTLE Analysis; Porter's Five Forces Analysis, Competitive Landscape, Analyst Overview of Investment Opportunities

Regions Covered

North America, Europe, APAC, Latin America, Middle East & Africa

 

This research report on the global high-resolution melting analysis market has been segmented based on Product and Service, Application, End User, and geography.

High-Resolution Melting Analysis Market - By Product and Service:

  • Reagents and Consumables
    • Specialized PCR Reagents
    • Intercalating Dyes
  • Instruments
  • Software and Services

The reagents and consumables segment dominated the market and occupied the major share of the global market in 2021. The HRM reagents and consumables exist as one of the high-potential product segments of the HRM analysis market. Factors such as cost-effectiveness and growing demand for research about cancer, HIV, and other genetic disorders. Rising investments from public and private organizations, funds, approvals, and a growing preference for precision medicine concepts promote the segment's growth rate.

High-Resolution Melting Analysis Market - By Application:

  • SNP Genotyping
  • Mutation Discovery
  • Species Identification
  • Pathogen Identification
  • Epigenetics
  • Other Applications

Based on application, the SNP genotyping segment holds the largest share in the high-resolution melting analysis market during the forecast period. The increasing investments primarily drive the segment's growth to conduct R&D, growing the number of patients suffering from infectious diseases, genetic disorders, and chronic diseases. In addition, the massive number of genotyping-based research and development activities is further predicted to boost the growth rate of the SNP genotyping segment.

High-Resolution Melting Analysis Market - By End User:

  • Research Laboratories and Academic Institutes
  • Pharmaceutical and Biotechnology Companies
  • Hospitals and Diagnostic Centres
  • Other End Users

Based on the end-user, the research laboratories and academic institutes segment captured a significant share of the global HRM analysis market in 2021. Factors such as growing demand for simple and effective molecular diagnostics and technological advancements from genotyping utilizing labeled probes for HRM promote the segment's growth. Growing demand for rapid and robust genotype analysis of higher samples for enormous-scale genotyping impacts segment growth. A favorable regulatory environment is a critical factor in the development of the academic research segment. Besides, according to the OECD, there has been a significant increase in the number of patents granted in biotechnology due to intellectual property importance. The development in molecular biology, biotechnology, and medicine is expected to increase the demand for human resource management products in the academic research segment.

High-Resolution Melting Analysis Market - By Region:

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • The Middle East and Africa

The high-resolution melting analysis market in North America accounted for the largest share of the global market in 2021. Furthermore, the domination of the North American region is projected to continue throughout the forecast period owing to increased investments to do R&D, high-quality healthcare infrastructure, and the availability of better reimbursement and healthcare options.

The European HRM analysis market captured the second-largest share in the global market in 2021 and is predicted to register a healthy CAGR during the forecast period owing to the rising awareness and establishment of HRM procedures.

However, the HRM analysis market in Asia-Pacific is estimated to grow at the highest CAGR during the forecast period because of exponentially greater population numbers. Therefore, the Asia-Pacific region is predicted to be the fastest-growing industry during the forecast period. The main factors contributing to this are strong population growth, increasing cancers, and other chronic diseases, which lead to significant unmet medical needs.

The Latin American HRM analysis market is predicted to witness a steady CAGR during the forecast period. Countries such as Brazil, Mexico, and Argentina are expected to have increased adoption of HRM analysis in the coming years, resulting in market expansion in this region.

The HRM analysis market in MEA is expected to register a moderate CAGR during the forecast period.

NOTABLE COMPANIES IN THIS MARKET:

The significant players in the global high-resolution melting analysis market include Thermo Fisher Scientific Inc. (U.S.), F. Hofmann-La Roche Ltd. (Switzerland), Bio-Rad Laboratories (U.S.), and QIAGEN N.V. (Netherlands). Other players in the market include Agilent Technologies Inc. (U.S.), bioMérieux S.A. (France), Illumina, Inc. (U.S.), Meridian Bioscience, Inc. (U.S.), Novacyt (France), Azura Genomics (U.S.), Canon Biomedical (U.S.), and PREMIER Biosoft (U.S.),

RECENT HAPPENINGS IN THIS MARKET:

  • In October 2020, Bio-Rad Laboratories, Inc. announced the global launch of its CFX Opus 96 and CFX Opus 384 real-time PCR systems, as well as BR.io, a platform for analysis, data management, and cloud-based instrument connectivity.
  • In September 2020, PREMIER Biosoft announced the release of GlycanExplorer ™ software version 1.0. This software was designed in alliance with Thermo Fisher Scientific to characterize biotherapeutic glucans. 
  • In September 2020, Meridian Bioscience, Inc., a significant supplier of diagnostic test solutions and critical raw materials for the life sciences, is gratified to announce the launch of a new pair of anti-SARS-CoV-2. Highly sensitive to trimeric spike protein to promote the improvement of COVID-19 tests from patient saliva.

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FAQ's

What was the size of the high-resolution melting analysis market worldwide in 2021?

The global high-resolution melting analysis market size was valued at USD 278.8 million in 2021.

What is the growth rate of the global high-resolution melting analysis market?

The global high-resolution melting analysis market is anticipated to grow at a CAGR of 3.6% from 2022 to 2027.

Which segment by application held the promising share in the high-resolution melting analysis market?

Based on application, the SNP genotyping segment had the most significant share of the global market in 2021.

Who are the leading players in the high-resolution melting analysis market?

Thermo Fisher Scientific Inc. (U.S.), F. Hofmann-La Roche Ltd. (Switzerland), Bio-Rad Laboratories (U.S.), and QIAGEN N.V. (Netherlands). Other players in the market include Agilent Technologies Inc. (U.S.), bioMérieux S.A. (France), Illumina, Inc. (U.S.), Meridian Bioscience, Inc. (U.S.), Novacyt (France), Azura Genomics (U.S.), Canon Biomedical (U.S.), and PREMIER Biosoft (U.S.) are some of the notable companies in the high-resolution melting analysis market.

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