North America Protein expression Market Research Report – Segmented By Expression Systems, Products, Application, End User, and country (United States, Canada and Rest of North America) - Industry Analysis on Size, Share, Trends, COVID-19 Impact & Growth Forecast | 2024 to 2029

Updated On: January, 2024
ID: 735
Pages: 133

North America Protein Expression Market Size (2023 to 2028)

The protein expression market size in North America was worth USD 910.56 Million in 2023 and is estimated to be growing at a CAGR of 7.36% to reach USD 1298.74 Million by 2028.

Protein expression is the process of altering, synthesizing, and controlling the proteins in living organisms. Proteins are controlled and manufactured depending upon the practical need in the host cell. Biotechnology-based companies create novel therapeutics with negligible side effects, thereby generating a huge market for Protein expression.  

Factors such as an increase in the pharma division’s research and development movement, prospects in proteomics, rising rates of chronic diseases, and government initiatives drive the expansion of the North American protein expression market. In addition, this regional market is also expected to be aided by the growth of the biologics market worldwide. The increasing support from private and public organizations through biotechnology investments is undoubtedly a key driver helping the North American protein expression market. The market's growth is also expected to be accelerated by an increase in the number of research institutes in the biosciences industry. In addition, the rising prevalence of successful treatment approaches is having a substantial impact on market growth.

The rising prevalence of chronic disorders across the region is another significant factor expected to push the market forward. Furthermore, as people become more aware of the negative consequences of molecular drugs, they are turning to biologics, boosting the demand for protein expression. The continued investment in genomics and proteomics by manufacturers and government is projected to generate attractive prospects for the protein expression market in the North American region to develop during the forecast period.

However, the expansion of the protein expression market in the North American region is predicted to be hampered by expensive product development costs and a complex regulatory environment. Over the projection period, the high cost of protein expression systems and the absence of effective techniques for post-translational modifications are projected to limit the market growth.

This research report on the North American protein expression market has been segmented and sub-segmented into the following categories:

By Expression Systems: 

  • Yeast Expression
  • Insect Expression
  • Cell-Free Expression
  • Bacterial Expression
  • Algal Expression
  • Mammalian Expression


  • Reagents
  • Services
  • Instruments
  • Others

By Application: 

  • Industrial Proteins
  • Cell Culture
  • Research
  • Therapeutic Proteins
  • Transfection Technologies
  • Others

By End User: 

  • Biotechnology
  • Pharmaceutics
  • Academia

By Country: 

  • The United States
  • Canada
  • Rest of North America

Geographically, the protein expression market in the North American region led the global market in 2020. The increase in capital income in both developed and emerging countries boosts market demand. In addition, pharmaceutical companies increased vaccines and antibody manufacturing rates are projected to outshine the market demand. According to the American Cancer Society’s January 2022 report, there will be an expected 1,898,160 new cancer cases, with 608,570 individuals dying from it. The growing need for gene and monoclonal antibody-based therapies in treating diseases including cancer, rare diseases, and other disorders is also propelling the North American protein expression market in the area.

The U.S. protein expression market dominated the North American market in 2020, and it is more likely to continue its dominance throughout the forecast period. The U.S. accounts for over 70% of the whole market region. The market growth is driven by increasing investments in research, rising usage of protein technology, and the rapidly evolving pharmaceutical industries. Furthermore, the presence of many key market participants in the U.S. is also helping the market to register a better growth rate. In addition, in the United States, opportunities in proteomics have boosted the market even further.

On the other end, the Canadian protein expression market is expected to do well during the forecast period. According to Statistics Canada’s “The Canadian Research and Development Pharmaceutical Sector” report from May 2022, the pharmaceutical sector contributed nearly USD 15 billion in value to the Canadian economy in 2018 while spending between USD 1.5 billion and USD 2 billion on research and development. The market is rising due to a growing patient population and increased research and development spending in the region.


Companies playing a dominant role in the North America Protein Expression Market profiled in this report are Agilent Technologies, Life Technologies Corporation, Bio-Rad Laboratories, New England BioLabs, Merck Millipore, Takara Bio, Thermo Fisher Scientific, and Promega Corporation.

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