Cell Sorting Market

Cell Sorting Market Size (2023 to 2028)

The global cell sorting market is estimated to be worth USD 348.76 Million by 2028 from USD 247.85 Million in 2023, growing at a CAGR of 7.07% during the forecast period.

Cell Sorting Market Share Insights:

• Based on technology, the FACS-based droplet sorting segment held the major share of the global market in 2022.
• Based on application, the research segment captured a major global cell sorting market share in 2022.
• Based on end-user, the research institutes segment had the leading global cell sorting market share in 2022.
• North America was the biggest regional market worldwide in 2022.

Cell sorting is an essential tool broadly used in many components of biomedical, biological research, and clinical therapy. Cell sorting is used to separate specific cells from the heterogeneous cell mixture. Cell sorting reagent allows the isolation of any cell from any species. Flow cytometers assist these systems in separating varied types of cells based on their properties. Fluorescence-Activated Cell Sorting (FACS) and cell imaging microscopes are the methods used by this system to characterize the various particles or cells. Cell-sorting system helps in rare cells' precise isolation from a sample of heterogeneous cells, thereby enabling the downstream study of cells for varied applications. Cell-sorting system has several applications, from malignancy genomics, primary research and clinical trials to forensic and non-invasive prenatal diagnosis.

MARKET DRIVERS:

The growing usage of cell sorting in the development of personalized medicine primarily drives the cell sorting market growth. Cell sorting technologies play a vital role in the development of personalized medicine processes. These technologies are used for the isolation and analysis of specific cells, such as tumor cells, immune cells and stem cells. The analysis of some of the rare cells that are often present in the human body in a less number and complicated to study using traditional technologies is required for the development of personalized medicine. In such situations, cell sorting technologies have been used to study such rare cells. Cell sorting technologies are also used for the development of immunotherapy to treat cancer patients and regenerative medicine to replace or regenerate damaged or diseased cells, tissues or organs.

Technological advancements further propel the cell sorting market growth. The market participants in cell sorting have developed advanced cell sorting systems that offer higher throughput, improved sensitivity and greater accuracy. Due to these benefits, the adoption of these cell sorting technologies has improved significantly in the research and clinical settings in recent years and this trend is likely to continue in the coming years and contribute to the cell sorting market growth.

The growing funding from governmental and non-governmental organizations to conduct R&D in the life sciences industry including cell sorting, the rising prevalence of chronic diseases, such as cancer, autoimmune diseases and infectious diseases, growing adoption of flow cytometry in research and the emergence of microfluidics-based cell sorting technologies that offer higher throughput, improved precision, and greater flexibility compared to traditional cell sorting systems boost the cell sorting market growth. The growing demand for cell-based assays in drug discovery and development, rising demand for biologics and biosimilars, increasing prevalence of infectious diseases, such as COVID-19, rising focus on stem cell research and increasing adoption of single-cell analysis further promote the market growth.

MARKET RESTRAINTS:

High costs associated with cell sorting instruments are one of the key factors hampering market growth. The scarcity of skilled professionals and the technological complexity of cell sorting hinder market growth. The stringent regulatory environment, limited throughput of cell sorting instruments, the competition from the alternative technologies available for cell analysis and sorting, including flow cytometry and microfluidic devices, and ethical concerns about the use of cell sorting technologies further inhibit the market growth.

Impact of COVID-19 on the global cell sorting market:

COVID-19 is a newly discovered novel coronavirus that causes an infectious disease. The disease has spread to almost every nation since the COVID-19 virus outbreak in December 2019, prompting the World Health Organization to declare it a public health emergency. Cell sorting is a technique that involves separating cells from an organism and sorting them according to their type. Differences in cell size, surface protein expression, and morphology are used to distinguish the cells. Cell sorting is a complicated mechanism of analysis in which fluorophore-conjugated antibodies are isolated from one another based on which fluorophore they were stained with. The increasing incidence of lung, colorectal, breast, and liver cancers, among others, is expected to speed up cancer cell-sorting procedures. In addition, many laboratories are interested in the production and clinical trials of the SARSCoV2 vaccine. By sorting unfixed antigen-specific lymphocytes, laboratories will be responsible for a significant part of this initiative. As a result, it's important and timely that we understand risk assessment and proven infectious cell sorting procedures.  As a result, the cell sorting market had moderate growth during this pandemic.

REPORT COVERAGE:

This research report on the global cell sorting market has been segmented and sub-segmented based on the technology, product, application, end-user, and region.

Cell Sorting Market - By Technology:

• FACS-based Droplet Sorting
• MACS
• Microfluidics

Based on the technology, the fluorescence-based droplet cell sorting segment had the largest share of the global cell sorting market in 2022. FACS offers fast, objective, and quantitative recording accuracy and complete applications, which surge the segment growth globally. On the other hand, high costs associated with fluorescence-based droplet cell sorting are expected to inhibit the segment's growth rate during the forecast period.

The microfluidics segment is projected to showcase the fastest CAGR due to new products invention, which is driving high demand. In addition, the cost-effective nature of microfluidics is further boosting the adoption of this technology and resulting in the segment's growth.

Cell Sorting Market - By Product:

• Cell Sorters
• Reagents
• Consumables

Based on the product, the cell sorters segment captured the leading share in the global cell sorting market in 2022 and is expected to dominate the market throughout the forecast period. The invention of new instruments has improved the sorting procedure, leading to quick results.

The reagents and consumables segment had a considerable share in the global cell sorting market in 2022 and is expected to hold a strong foothold during the forecast period. Reagents and consumables are used in various applications, one of the key factors propelling the segment’s growth.

Cell Sorting Market - By Application:

• Research
• Clinical

Based on the application, the research segment is expected to grow at a promising CAGR due to increasing cancer research. The clinical application segment is anticipated to have a lucrative growth rate as a frequent increase in diseases like HIV and cancer. In addition, the increasing adoption of cellular analysis in research activities is primarily driving the segment’s growth.

The clinical application is anticipated to do well during the forecast period. The increasing patient poor suffering from various diseases worldwide fuels the segment’s growth.

Cell Sorting Market - By End-User:

• Research Institutes
• Biopharma Companies
• Medical Schools

The research institutes segment accounts for the largest share of the cell sorting market throughout the forecast period based on the end-user. The segment is driven by the growing number of research activities in cellular analysis, increasing cell-based therapies and applications, and growing investments and funds in cancer and stem cell research to propel the segment's growth globally.

Medical schools are estimated to have considerable growth in the cell sorting market due to increasing collaborations, mergers, and acquisitions between pharma and biotech companies, which leads to growth in several research activities.

Cell Sorting Market - By Region:

• North America
• Europe
• Asia Pacific
• Latin America
• The Middle East and Africa

Regionally, the cell sorting market in North America is estimated to have the largest share during the forecast period, followed by Europe and Asia-Pacific. Huge investments in pharmaceutical and biotechnology companies and the growing obtainment of cell sorting towards cancer research are expected to drive the growth of the North American market. The U.S. cell sorting market is expected to lead the North American market due to the growing incidence rate of cancer, which drives this region's growth. Nearly 133 million Americans, which means more than 40% of the population, are affected by chronic diseases.

The cell sorting market in Europe was the second-largest regional market worldwide in 2022 and is predicted to grow at a promising CAGR during the forecast period. A strong focus on biomedical research and the presence of several leading research institutes and academic centers involved in cutting-edge studies in Europe majorly drive the European cell sorting market growth. The presence of well-developed healthcare systems and the rising prevalence of chronic diseases fuels the demand for advanced cell sorting technologies for diagnostic and therapeutic purposes, which is contributing to the growth rate of the European market. The rising support for life sciences research from the governments of European countries, the increasing number of collaborations between academic and industrial entities and the presence of key market players further boost the growth rate of the European market.

The cell sorting market in Asia-Pacific is projected to have the highest growth potential by 2028. Emerging markets in developing countries like India and China have become attractive places for companies developing and marketing cell sorters. Factors contributing to the growth of the Asia-Pacific cell sorting technologies market include increased funding for cancer research activities and increasing support from the government to reinforce the biotechnology industry.

The cell sorting market in Latin America accounted for a considerable share of the global market in 2022 and is estimated to grow at a healthy CAGR during the forecast period owing to the rising burden of chronic diseases, such as cancer and infectious diseases and increasing demand for advanced diagnostic and research tools like cell sorting technologies.  High capability of stem cells and growth in cancer research and advancements in technology and increased chronic diseases in the cell sorting market during the analysis period. Brazil is one of the largest leading countries in this region, followed by Mexico, Argentina, and Columbia.

The cell sorting market in the Middle East & Africa is anticipated to have the least and slow growth rate in the cell sorting market of this region.

KEY MARKET PARTICIPANTS:

Some of the notable participants leading the global cell sorting market covered in this report are Becton, Dickinson, and Company (U.S.), Bio-Rad Laboratories, Inc. (U.S.), Beckman Coulter, Inc. (U.S.), Miltenyi Biotec GmbH (Germany), Affymetrix Inc. (U.S.), Sony Biotechnology, Inc. (U.S.), Sysmex Partec GmbH (Japan), Cytonome/ST, LLC (U.S.), On-Chip Biotechnologies Co., Ltd. (Japan), and Union Biometrica, Inc. (U.S.)

RECENT MARKET HAPPENINGS:

• In April 2019, Miltenyi Biotec introduced a new platform for fully automated and high-content imaging at the AACR ANNUAL MEETING 2019 in ATLANTA, the MACSima Imaging Platform.  
• In June 2019, Beckman Coulter Life Sciences announced its acquisition of Cytobank, a software platform for multi-parametric single-cell data analysis, software as a service company based in Santa Clara, California. 
• In March 2019, the reconstruction of kidney tubules derived from human kidney adult stem cells in microfluidic chips. The tubules show cilia at the luminal side and ion transporters at the blood side. 
• In January 2019, STEMCELL Technologies launched mTeSR Plus, an enhanced version of mTeSR 1, a widely accepted feeder-free human pluripotent stem cell maintenance medium. It has undergone beta testing with several Stem Cell Coredinates group members. 
• In March 2018, Terumo BCT, a U.S.-based global leader in blood component and cellular technologies, selected services and consulting firm Capgemini to set up two global innovation and development (I&D) centers in India. 
• In October 2018, UniCAR- Therapy Bio-Medicine technology chose Terumo BCT and its cell expansion devices to implement automation in its cell therapy manufacturing process for chimeric antigen receptor CAR T-cell therapies.