Digital PCR and qPCR Market

Digital PCR and qPCR Market Size (2023 to 2028)

The global Digital PCR and qPCR market is expected to grow at a CAGR of 8.96% from 2023 to 2028 and the market size is expected to be worth USD 6.67 bn by 2028 from USD 4.34 billion in 2023.

Digital PCR and qPCR Market Share Insights:

• Based on product, the consumables and reagents segment accounted for the largest share of the global digital PCT and qPCR market in 2022.
• Based on technology, the quantitative PCR segment led the market in 2022.
• Based on application, the research and forensics segment dominated the market in 2022.
• Based on end-user, the pharmaceutical and biotechnological companies segment accounted for the leading share of the market in 2022.
• The North American region held 40.2% of the global market share in 2022.
• The European region accounted for a notable share of the worldwide market in 2022. 

Polymerase Chain Reaction (PCR) is an analytical process extensively used in molecular biology to make multiple copies of DNA segments. PCR can generate millions of copies from one DNA segment.

MARKET DRIVERS:

The increasing adoption rate of real-time PCR and digital PCR to diagnose genetic disorders and infectious diseases such as tuberculosis, malaria, and others is propelling the global digital PCR and qPCR market growth.

Digital PCR and qPCR devices are highly efficient for estimating disease-causing microbes and diagnostics analysis. The emergence of innovative and advanced genomic analysis products worldwide and the growing focus of government and private organizations to develop novel and innovative digital PCR and qPCR products are favoring the market growth.

In addition, the growing incidence of genetic disorders and other chronic diseases such as cancer and technological advancements, growing healthcare expenditure, and emerging economies such as China, Canada, India, U.K, Japan, and other developed and developing countries across the world are anticipated to support the growth rate of the digital PCR and qPCR market. Benefits offered by digital PCR over traditional PCR, such as accuracy, better sensitivity, and enhanced flexibility, are estimated to promote the global digital PCR and qPCR market growth during the forecast period. In addition, increasing qPCR consumables, reagents, and other clinical applications is a plus to the market's growth rate.

In the recent past, the increasing demand for fast diagnostics, the frail population, growing patient count suffering from infectious and genetic disorders such as cancer, HIV, and Hepatitis are expected to have a favorable impact on the global digital PCR and qPCR market growth. In addition, the growing investments from market participants to conduct R&D and develop advanced PCR products are expected to favor the market’s growth rate in the coming years.

MARKET RESTRAINTS:

However, technical glitches and the high initial costs associated with digital PCR & qPCR are restraining the market growth. In addition, the high costs associated with the instrument's need for capital investments on a large scale to develop advanced devices further limit the market’s growth rate. Technical limitations related to PCR also control the adoption rate, another major factor challenging the growth of the global digital PCR and qPCR market.

Impact of COVID-19 on the global digital PCR and qPCR market:

COVID-19 is a global public health emergency unlike any other, affecting almost every industry. But COVID-19's sudden outbreak has driven some healthcare firms to find a solution for deadly and harmful diseases. The PCR industry has been positively impacted due to the virus and is forecasted to hit new growth heights shortly. Polymerase chain reaction (PCR) technology is used in various applications, including DNA cloning, genetic disease identification, functional gene analysis, infectious disease detection, and forensic sciences. The use of digital PCR and real-time PCR in diagnostic and drug development has seen an increase in demand in the recent past. Digital PCR is most used to distinguish allele expression, monitor viral infection in individual bacterial cells, and detect fetal DNA in the bloodstream.

To detect COVID-19, industry players are concentrating on developing droplet digital PCR kit tests. Regulatory agencies have also shown interest in approving these experiments to combat the COVID-19 pandemic's consequences. Several businesses have altered their business models to deal with the pandemic. As a result, the company increased its emphasis on research and development to improve COVID-19 droplet digital PCR kits, aiding revenue growth. Thermo Fisher developed multiplex PCR kits and assays for diagnostics and testing applications to tackle the COVID-19 outbreak. The company obtained an emergency use authorization from the U.S. Food and Drug Administration for its SARSCoV2 multiplex real-time PCR test, and in 2020, it introduced AcroMetrix Coronavirus 2019 RNA Control. Considering all these factors, the global digital PCR and the qPCR market have had favorable growth due to the impact of COVID-19.

REPORT COVERAGE:

This research report on the global digital PCR and QPCR market has been segmented and sub-segmented based on the product, technology, application, end-user, and region.

Digital PCR and qPCR Market – By Product:

• Consumables & Reagents
• Instruments

Based on product, the consumables and reagents segment dominated the global market in 2022 and is anticipated to be contributing significantly to the growth of the global digital PCR and qPCR market during the forecast period owing to factors such as increased applications of qPCR reagents such as assay kits and master mixes and increasing investments from private and public organizations. 

Digital PCR and qPCR Market – By Technology:

• Quantitative PCR
• Digital PCR

Based on the technology, the quantitative PCR segment is expected to account for the largest share during the forecast period due to the rising focus on enhancements of Point of care (POC) platforms, the ongoing stipulation in areas like genetic variation analysis, and gene expression analysis and genotyping.

On the other hand, digital PCR is expected to showcase a healthy CAGR in the coming years. Digital PCR is a next-generation testing process that assists inaccurate quantification of nucleic acids. These systems provide better sensitivity and precision related to other PCR strategies based are likely to strengthen the growth during the forecast period.

Digital PCR and qPCR Market – By Application:

• Tumors
• Blood Testing
• Pathogen Detection
• Research & Forensics

Based on the application, the research and forensics segment is projected to lead the global digital PCR and qPCR market during the forecast period owing to the increased government and other private organizations for the research and the funds and investments offered.

The blood testing segment is also anticipated to perform well during the global digital PCR and qPCR market forecast period. Increasing the utilization of qPCR in disease diagnosis, the swelling of infectious and genetic diseases, and mounting public attention on early and efficient disease diagnosis and treatment make this segment grow higher.

Digital PCR and qPCR Market – By End User:

• Hospitals
• Research & Forensic Centers
• Pharmaceutical & Bio-Technological Firms
• Academic Institutions

Based on end-user, the pharmaceutical and biotechnological companies segment is forecasted to hold a significant share of the global digital PCR and qPCR market during the forecast period. It is expected to register a healthy CAGR.

Digital PCR and qPCR Market – By Region:

• North America
• Europe
• Asia Pacific
• Latin America
• The Middle East and Africa

Geographically, the North American digital PCR and qPCR market led the global market in 2022, followed by Europe and the Asia Pacific. Owing to technological developments and increasing investments from the private sector, investments are anticipated to fuel the market’s growth rate in the North American region. In addition, the growth of the North American market is further driven by factors such as growing support and funding from governments to upgrade qPCR and digital PCR technology, increasing cancer patient count, and an ongoing cutback in the average price of gene sequencing.

The digital PCR and qPCR market in Europe held the second-largest global market share in 2022 and is anticipated to hold a substantial share of the global market during the forecast period. A wide range of applications of qPCR and digital PCR technologies utilized in areas such as human genetic testing and forensic sciences are some factors propelling the market growth in the European region.

The digital PCR and qPCR market in Asia-Pacific is predicted to grow at a prominent CAGR during the forecast period. An increase in the patient count suffering from chronic and infectious diseases integrated with growing alertness amid patients regarding early diagnosis of the disorders is projected to boost the market growth globally. India is projected as one of the capable markets in the APAC in digital PCR and qPCR market, especially for the country's everyday importance of cancer and cardiovascular diseases. According to the International Agency for Research on Cancer, the country reported 1.2 million cancer cases in 2018, the country's primary cause of death rate.

The digital PCR and qPCR market in Latin America is projected to have a steady growth rate during the forecast period. YOY growth in the aging population, a considerable number of vital regional players, and growing R&D applications. The Brazilian market is predicted to lead the Latin American market during the forecast period due to the growing demand for quick diagnostics and quickly advanced technologies.

The digital PCR and qPCR market of the Middle East & Africa region is anticipated to have a minimal share during the forecast period. However, rapid technological advancements like high-performance development bolstered the region's market growth.

KEY MARKET PARTICIPANTS:

Some of the notable companies dominating the Global Digital PCR and qPCR Market profiled in this report are Thermo Fisher Scientific Inc., F Hoffman-La Roche Ltd., Bio-Rad Laboratories, Qiagen N.V., Taraka Bio Inc., Affymetrix Inc., Agilent Technologies Inc., Fluidigm Corporation, Danaher Corporation, and Becton & Dickson Company.

HAPPENINGS IN THIS MARKET IN THE RECENT PAST:

• Recently, HDPCR multiplexing technology has been developed that combines proprietary data science algorithms that enrich the multiplex levels of common real-time and digital PCR to detect 5-50 target sites in a reaction at a low cost. In addition, a profusion of bacterial allosteric transcription factors (sTF) has been discovered to study various tiny molecules. A TF-based nicked DNA segment-assisted signal transduction system (a TF-NAST) is used.
• Agilent technologies inc. completed the acquisition of scientific co. Ltd. in 2018. With this deal, Agilent Technologies Inc. expanded its distribution channel in South Korea and other Asian Markets.
• Abbott Company collaborated with the Japanese Red Cross Society in 2019. As a result, Abbott has locked the agreement to supply plasma screening and blood screening devices and consumables for tests and serological instrumentation in Japan. This collaboration helps Abbott expand its distribution network and share the company's value in Japan. 
• Qiagen Company started developing a series of technically advanced systems for digital PCR in 2019.