qPCR Reagents Market

Global qPCR Reagents Market Size (2022 to 2027)

The global qPCR reagents market is estimated to be worth USD 1.76 billion in 2022 and is forecasted to grow at a CAGR of 7.75% to reach USD 2.55 billion by 2027.

Global qPCR Reagents Market Share Insights:

• Based on the detection method, the probe & primer-based qPCR segment accounted for the major share of the market in 2021.
• Based on the packaging type, the qPCR core kits segment had the leading market share in 2021.
• The North American qPCR market was worth USD 560 million in 2021.
• The qPCR market in Europe is estimated to value at USD 740 million by 2027.
• The qPCR market in Asia-Pacific is expected to grow at a CAGR of 9.7% from 2022 to 2027.

A qPCR is also known as a real-time polymerase chain reaction and is a laboratory method of molecular biology dependent on the polymerase chain reaction. It involves screening the magnification of a specific DNA segment while the polymerase chain reaction is undergoing. It can be applied in two variations, the semi-quantitative real-time polymerase chain reaction and the quantitative real-time polymerase chain reaction. Applications of qPCR include gene expression, gene typing, miRNA analysis, pre-amplification, and virus detection. The process is usually carried out in a thermal cycler, which can illuminate each sample with a light beam of at least one specified wavelength. In addition, the thermal cycler can rapidly heat and chill samples.

MARKET DRIVERS:

Factors such as the increasing patient population affected by genetic disorders and other infectious diseases, the growing geriatric population, and the advancements in technology in the life sciences are propelling the qPCR reagents market growth.

The prevalence of genetic disorders is significant, and an estimated six out of 10 people face health difficulties with some genetic connection. The impact of these health difficulties can range from mild to very severe. For example, an estimated 9% of the total population of the United States is suffering from one of the infectious diseases. According to the statistics published by the World Health Organization (WHO), 350 million people worldwide are affected by genetic disorders. In addition, 1 in 800 live births with Down syndrome, 1 in 2500 live births with cystic fibrosis, 1 in 500 African American births with sickle cell anemia, 1 in 300 Ashkenazi Jewish births with Tay Sachs disease, and 1 in 5000 male births with hemophilia are suffering from some genetic disorder.

In addition, other factors contributing to the qPCR reagents market growth include the rising funding from the public and private sectors and conferences and workshops held on the topic. In addition, growing market penetration in emerging countries and moving from plant-derived to genome-based drug discovery generate profitable market opportunities. The global qPCR reagents market growth is further driven by increasing public and private investment, funding and grants for PCR-based research, and the success of the human genome project.

Furthermore, the growing penetration of international life science companies in the qPCR reagents market, growing policy focus on improved understanding of gene-based disease diagnosis and treatment, increased governmental and non-governmental funding for developing new qPCR technologies, and supporting cancer research provide growth opportunities to the qPCR reagents market.

MARKET RESTRAINTS:

However, the technical limitations associated with qPCR and the lack of technical expertise to operate qPCR equipment are the major factors restraining the market growth. In addition, the high cost of qPCR is expected to impede market growth.

Impact of COVID-19 on the global qPCR reagents market:

The introduction of the new coronavirus (COVID-19) has rapidly developed during the pandemic period. As a result, the global qPCR reagents market has accelerated growth due to COVID-19. The continuous COVID­19 pandemic endures establishing demand for diagnostic screening. RT-PCR AND qPCR reagents are used to conduct sample tests to confirm the COVID-19 status in a person. qPCR is one of the qualitative recognitions of nucleic acids from SARS-CoV-2. The potentiality of RT-qPCR is examined for recognizing at least one single positive sample with a massive count of negative examples. However, the qPCR is a high-cost assay unavailable for most diagnostic centers and laboratories worldwide. Nonetheless, With the support of COVID-19, the global qPCR market is expected to grow at a much better pace during the forecast period.

REPORT COVERAGE:

This research report on the global qPCR reagents market has been segmented and sub-segmented based on detection method, packaging type, Application, end-user, and Region.

qPCR Reagents Market – By Detection Method:

• Dye-Based qPCR Reagents
• Probes and Primer-Based qPCR Reagents 

Based on the detection method, the Probe-based qPCR reagents segment is anticipated to dominate with the highest growth rate during the forecast period. This is because it offers many advantages, such as multiplexing, which can detect different targets simultaneously. 

However, the dye-based qPCR reagents used in DNA amplification are also expected to show significant growth during the forecast period. The Dye is used to create a fluorescence background in DNA amplification which becomes stronger the more the DNA binds to dsDNA. Therefore, the technique's efficiency is helping it gain revenue during the forecast period. 

qPCR Reagents Market – By Packaging Type:

• qPCR Core Kits
• qPCR Mastermixes

The segment of qPCR Core Kits is expected to lead the global qPCR reagents market by packaging type during the forecast period. Factors such as low prices for core kits (as opposed to Mastermixes), versatility for end-users (as it is best suited for researchers to build independent response protocols), and growing private-public funding for life science research are strongly favoring the growth of the segment.

However, due to its several advantages, the qPCR master mixing segment is expected to grow significantly during the forecast period. The segment helps the researcher collect a perfect mix of DNA polymerase, dNTPs, MgCl2, and buffer without mixing errors. It helps reduce the time consumed in research, and it also prevents the possibility of sample contamination. Therefore, it is a straightforward and accessible method to help the segment grow. 

qPCR Reagents Market – By End User:

• Hospitals & Diagnostic Centre
• Research Laboratories & Academic Institutes
• Pharmaceutical and Biotechnology Companies
• Clinical Research Organizations
• Forensic Laboratories

Based on End-User, the hospital and diagnostic centers segment is expected to account for the leading share in the global qPCR reagents market. Due to strengthening the healthcare system for successful diagnosis and treatment of diseases, increasing qPCR reagents for diagnostic applications, and other advantages offered by qPCR.

However, the research laboratories and academic institutes market is expected to grow significantly during the forecast period due to the rising R&D activities in the polymerase chain reaction market. The increasing interest in developing new drugs and research results are helping the segment's growth. 

qPCR Reagents Market – By Application:

• Diagnostics
• Research
• Forensic

Based on the Application, the research application is projected to dominate the market between 2021 to 2026. Furthermore, it will continue to dominate in the forecast period due to widespread use in research areas such as stem cells, microbiology, and agriculture.

However, the forensic segment is also expected to show significant growth during the forecast period due to the applications of qPCR in forensic requirements. Forensic work requires studying the evidence found at the scene in cases to determine several factors about the victim or the preparator. The analysis of each DNA sample has a standard short tandem repeat (STR) analysis which is done with the help of qPCR, thus supporting segment growth. 

qPCR Reagents Market – By Region:

• North America
• Europe
• Asia-Pacific
• Latin America
• The Middle East and Africa

Geographically, the global qPCR reagents market was dominated by North America in 2019, with the Region accounting for 38% of the overall market share. North America was followed next in line by Europe and Asia-Pacific. Asia-Pacific is expected to grow rapidly in the coming years, as is evident from the high CAGR value for the Region. Another market that shows promise in the coming years in Latin America.

The North American qPCR reagents market is strongly driven by the availability of advanced healthcare infrastructure, increasing public and private investments, and pharmaceutical and biotechnology companies. In the regional market, the United States recorded the largest share of the qPCR reagents market, and it is anticipated to witness a predominant share during the forecast period. This is because of the technological advances in the life sciences sector, increasing healthcare spending, and favorable reimbursement policies. On the other hand, the Canadian qPCR reagents market is projected to showcase a considerable share in the coming years.

The European qPCR reagents market was the second-largest shareholding region in the global qPCR reagents market in 2020. The occurrence of infectious diseases, increasing research and development activities, and the accomplishment of the human genome project are fuelling regional market growth. In addition, the emerging countries in the Region, such as Germany, the UK, Spain, Italy, and France, are expanding the European regional market with a significant market share. Germany accounts for the largest share of the European qPCR reagents market owing to the technological developments in life sciences sectors, key market payers, and the prevalence of chronic diseases.

On the other hand, the APAC qPCR reagents market has been one of the fastest-growing regions globally in the qPCR reagents market. However, it is anticipated to grow during the forecast period. The market growth is expected to be driven by improving the healthcare sector, raising awareness related to gene-based disease treatment, and expanding the geriatric population. Moreover, highly populated emerging countries such as China and India contribute to the APAC regional market growth. Over the forecast period, China held the largest share of the qPCR market and more likely witnessed a prominent share during the forecast period. In addition, the growing geriatric population, increasing prevalence of infectious diseases, and growing life sciences industries boost the market growth. 

The Latin American qPCR reagents market is expected to grow at a CAGR of 8.44% from 2022 to 2027.

The qPCR reagents market in the MEA region is expected to be worth USD 440 million by 2027.

KEY MARKET PLAYERS:

A few promising companies in the global qPCR reagents market profiled in this report are Thermo Fisher Scientific, Bio-Rad Laboratories, Qiagen N.V., F. Hoffmann-La Roche Agilent Technologies Inc., Takara Bio, Affymetrix Inc., Promega Corporation, Sigma-Aldrich Corporation, and Quanta Biosciences.

RECENT HAPPENINGS IN THIS MARKET:

• In October 2022, a new high-throughput and comprehensive method for identifying infectious diseases based on syndromic markers were developed and validated by Takara Bio USA, Inc. and BioExcel Diagnostics, two innovative life science reagent and instrument companies. Takara Bio USA, Inc. is a wholly-owned subsidiary of Takara Bio Inc.
• In September 2022, Integrated DNA Technologies introduced the PrimeTimeTM 1-Step 4X Broad-Range qPCR Master Mix to address the growing demand for an inhibitor-resistant, high-performance master mix that enables direct amplification of unprocessed samples.
• In May 2022, Anitoa Systems, a US-based start-up, released a portable RT-PCR molecular test to detect dengue virus infections. The novel test uses a member of the Maverick qPCR series of four- to six-channel tiny footprint real-time PCR equipment.