Polymerase Chain Reaction Market

Global Polymerase Chain Reaction Market Size (2024 to 2029)

The size of the global polymerase chain reaction market was valued at USD 9.42 billion in 2024. It is estimated to be growing at a CAGR of 6.60% to reach USD 12.97 billion by 2029.

The polymerase chain reaction duplicates or produces billions or millions of copies of a particular DNA/ genetic sample. This process helps scientists to collect a minute sample and produce billions of copies of genetic material. The molecular biology field utilizes this polymerase chain reaction more than any other field. These polymerase chain reaction technologies duplicate the millions of copies of a piece of deoxyribonucleic acid or any other genetic material. These technologies identify criminals and child identities in the forensics department. These devices also diagnose tuberculosis, AIDS, Lyme, and middle ear infections. Also, in biotechnology and microbiology, and the academic field, these polymerase chain reaction technologies are used to identify microorganisms and their culture and cause diseases. Polymerase chain reaction technologies are also used in genetic engineering, molecular biology, and research. For example, polymerase chain reaction technologies play a significant role in drug discovery and clinical diagnostics and help scientists in their studies. In addition, polymerase chain reaction technologies also play a significant role in DNA sequencing and cloning.

MARKET DRIVERS

The rising prevalence of infectious diseases and increased viral and other chronic infections with the highest spread ratio propel the global polymerase chain reaction market growth.

According to the Centre for Disease Control and Prevention, around 5000 deaths have been noted due to influenza infection registered in the United States, according to reports as of 2015. However, even with the highest spread ratio, this rising number of infections and other diseases can be curbed by PCR technique developments. Hence, this is an augmenting factor for market growth. In addition, an increase in polymerase chain reaction adoption for various drug developments, disease identifications, and research applications is expected to boost the global polymerase chain reaction market growth.

The growing population suffering from genetically inherited diseases is another factor contributing to the PCR market growth.

The continuous increase in the cases of genetically inherited diseases such as thalassemia, cystic fibrosis, haemophilia and others have increased the demand for the polymerase chain reaction services due to the use of procedures like prenatal genetic testing, which allows diagnosis and finding treatments for such problems before their advancement in the womb of the mother. The WHO estimates that 10 out of every 1000 people are affected by a genetic disorder, further promoting the importance of the market. 

An increase in the number of research developments and funding activities in gene therapy and other genetics and biological fields also boosts the market’s growth rate. Furthermore, the growing adoption of personalized medicines, personalized health check-ups, and various health benefits due to schemes are further expected to accelerate the global polymerized chain reaction market. In addition, increasing awareness and acceptance of polymerase chain reaction technologies accelerate the market's growth rate.

MARKET RESTRAINTS

The rise in non-validated tests and other fraud systems is expected to hamper the global polymerase chain reaction market.

High costs associated with the PCR instruments and reagents are majorly hampering the polymerase chain reaction market growth. Due to these high costs, the affordability of PCR instruments and reagents has become difficult for smaller laboratories and institutions. The scarcity of skilled professionals that can operate and interpret the results of polymerase chain reactions is another major factor hindering the growth rate of the polymerase chain reaction market. The presence of alternative technologies for nucleic acid amplification such as loop-mediated isothermal amplification (LAMP) and digital PCR are limiting the adoption of PCR technology and the market’s growth rate. The stringent regulatory environment for PCR technology is further limiting the adoption of this technology among clinical settings, which is impacting the market growth negatively. Poor awareness levels among some researchers, clinicians, or policymakers regarding PCR technology is another major factor limiting the adoption of PCR technology and limiting the market growth.

REPORT COVERAGE

SEGMENTATION ANALYSIS

Global Polymerase Chain Reaction Market Analysis By Type

The PCR consumables segment had 69.7% of the global market share in 2023.

The PCR consumables segment is still looking lucrative and likely to continue its dominating position in the global market throughout the forecast period. High demand for genetic testing and technologically sophisticated diagnostic tests in countries with unmet health needs are propelling the expansion of PCR consumables segment in the global market. In addition, introducing new products will likely lead to the segment's development. For example, Biocore Co. Ltd. released the first dPCR-based NIPT kits to diagnose chromosomal anomalies in March 2018.

The PCR instruments segment is another major segment and is expected to register promising growth during the forecast period due to technological advancements in polymerase chain reaction instruments. 

Global Polymerase Chain Reaction Market Analysis By Application

The gene expression segment held 36.2% of the global market share in 2023.

Not being the largest segment in 2023, the gene expression segment is predicted to grow at the fastest CAGR in the global market during the forecast period. The domination of the gene expression segment is majorly driven by the application of genomics in the polymerase industry. In addition, genomes help determine the fundamental nature of several food products, helping establish their reaction to certain diseases and helping determine personalized diet treatments. Therefore, the gene expression segment is expected to grow significantly during the forecast period. 

The DNA fingerprinting segment is also expected to grow significantly during the forecast period due to the several advantages of DNA fingerprinting. The DNA fingerprint is unique to each individual and therefore is used in investigations from crime scenes with the collection of hair stands, nails, teeth, etc., which can all determine unique DNA. It is also used in court proceedings for paternity testing cases and biometrics and safety biotechnologies, thus pushing the market to grow.

REGIONAL ANALYSIS

North America captured 34.1% of the global market share in 2023 and emerged as the most dominating region in the worldwide market.

These two regions are relied upon to hold their position throughout the forecast period. The North American area was among the first to support and implement PCR-based applications to diagnose irresistible sicknesses, for example, HIV. Factors such as the establishment of new biotechnologies and pharmaceuticals, equipment and reagents necessary for carrying out this process, technological advancements, research and developments, and others drive market growth for the polymerase chain reaction market in North America. Favorable government regulatory guidelines and reimbursement programs further drive the North American market growth. The Department of Health and Human Services announced in February 2020 that the emergency use of diagnostics for COVID-19 diagnosis had been approved. The number of diagnostics products launched in the region improved due to this approval. In the regional market, the United States contributed the largest market share of polymerase chain reactions. The presence of advanced healthcare infrastructure and government initiatives are propelling the country's market growth. The Canadian polymerase chain reaction market is slightly contributing to regional market growth.

Europe is likely to be a notable region in the global PCR market.

Europe is estimated to be the second-largest regional market in the global polymerase chain reaction market during the forecast period. It is likely to maintain its growth in the next five years. Growth in healthcare expenditure and technological advancements in the healthcare sector are propelling market growth in the region. The UK, Germany, France, Spain, and Italy are the major growth contributors in the region. over the years, the UK accounted for the largest market share of the polymerase chain reaction market and is forecasted to grow throughout the forecast period.

Asia Pacific is predicted to showcase the most elevated CAGR during the forecast period.

The Asia Pacific holds a promising share of the global market due to its rapidly growing population and advancements in medical technologies. In addition, other factors include increased chronic diseases, increased adoption of personalized medicines, awareness in early detection of diseases, and increased market value for this market in the Asia Pacific region. Emerging countries like China, Japan, and India significantly contribute to the APAC market, and the support will likely be maintained throughout the forecast period.

The Latin American PCR market is predicted to hold a considerable share of the worldwide market during the forecast period. Brazil followed by Mexico captured the major share of the Latin American market in 2023 and the same is trend is predicted to continue during the forecast period.

The PCR market in MEA expects slow growth due to a lack of skilled staff, laboratories, and other industries, a lack of awareness of biotechnologies and drug developments, and a high literacy rate.

KEY PLAYERS IN THE GLOBAL POLYMERASE CHAIN REACTION MARKET

Companies leading the global polymerase chain reaction market profiled in the report are Beckman Coulter, Clontech Laboratories, Eppendorf, Fluidigm, PerkinElmer, bioMérieux, Harvard Bioscience, Maxim Biotech, Promega, and Siemens Healthcare.

RECENT HAPPENINGS IN THE GLOBAL MARKET

• In September 2022, Temasek invested $85 million in Molbio Diagnostics at a unicorn valuation. The Goa-based diagnostics chain Molbio Diagnostics Pvt. Ltd. has received an investment of $85 million (about 680 crores) from the Singaporean investment company Temasek. According to someone who knows the situation, the company will have a post-round valuation of $1.6 billion. The most recent fundraising consists of primary and secondary market transactions with partial exits from angel investors.
• In October 2022, Abbott received urgent FDA approval for the first commercial monkeypox test. Abbott is the first business to offer a commercial test under the EUA process. The Alinity m System from Abbott automatically completes each step required to run the test, including sample preparation and PCR assembly. Abbott created the method to speed up the testing process for infectious diseases. Abbott has out clinical evaluation research to substantiate the monkeypox test. The test's accuracy in detecting the presence of the monkeypox virus at two and four times the limit of detection was evaluated. All 36 positive samples had the virus, which Alinity m MPXV found. Additionally, the test accurately stated that the virus was absent from 35 test-negative samples.
• In October 2022, Provista Diagnostics successfully launched a suite of PCR testing services, according to Todos Medical. Gerald Commissiong, CEO of Todos Medical Ltd., informs Stephen Gunnion of Proactive that the company's CLIA/CAP accredited lab Provista Diagnostics has completed a pilot launch of a polymerase chain reaction (PCR) testing services in the small Florida town of Dunnellon. According to Commissiong's statement, Proactive, non-COVID-related testing will play a more significant role in Provista's business strategy as it prepares to introduce its breast cancer blood test, Videssa, in 2023.

DETAILED SEGMENTATION OF THE GLOBAL POLYMERASE CHAIN REACTION MARKET INCLUDED IN THIS REPORT

This market research report on the global polymerase chain reaction market has been segmented and sub-segmented based on type, application, and region.

By Type

• PCR consumables
• PCR instruments

By Application

• DNA fingerprinting
• DNA sequencing
• DNA cloning
• gene expression

By Region

• North America
• Europe
• Asia Pacific
• Latin America
• The Middle East and Africa