The size of the global In Situ Hybridization market was worth USD 621.78 million in 2020 and is estimated to be growing at a CAGR of 5.75% to reach USD 822.32 million by 2025. The market is showcasing evident potential in the mentioned forecasting period. The market continues to gain momentum with rapid development in the medical industry.
In situ hybridization (ISH) is a hybridization that involves a labeled complementary DNA, RNA, or modified nucleic acids strand to spot or localize a specific DNA or RNA sequence in a portion or part of tissue i.e., in situ. The effective techniques presently include: in situ hybridization to mRNA with oligonucleotide and RNA probes; analysis with light and electron microscopes; whole-mount in situ hybridization; double detection of RNAs and RNA plus protein; and fluorescent in situ hybridization to spot chromosomal sequences.
The global in situ hybridization market is primarily driven by the increased cases of diseases like Cancer and an increase in the overall geriatric population. The growing diagnosis of disease due to more availability of facilities to people has also boosted the market. Advancement in therapeutic applications has contributed significantly to the overall growth of the market. Rising government initiatives due to a large number of cases is also a positive factor influencing the market. Rising healthcare expenses due to increasing disposable income have increased the overall revenue of the market.
The development of high value in-situ hybrid technologies and the increased adoption of in situ hybridization in developing countries such as China, India, and others will create new opportunities for the global in situ hybridization market. The growth of the population affected with diseases across the world and the demand for an accurate and effective diagnosis of these diseases is expected to offer lucrative opportunities for the growth of the in-situ hybridization market during the forecast period. The increasing adoption rate of FISH probes in vitro for diagnosing various infectious diseases is likely to create growth opportunities during the forecast period.
The factors that challenge the growth of the in-situ hybridization market are higher research and development costs, strict government regulations, and the approval process are the main constraints of the in situ hybridization market.
Furthermore, market growth is expected to restrain by the high research and development costs associated with this market. Due to increased research costs, governments try to find less expensive solutions, so less money is allocated to research and development divisions. The governments also have implied strict regulations in this process due to the complexity of the procedure and its use in the market. It has led to a delay in approvals for the companies, thus restraining the in situ hybridization market. The lack of skilled professionals who can efficiently use this technique to detect the diseases at early stages also hampers the market growth. It will continue to do so if the significant initiative is not introduced to make the technique more familiar.
COVID-19 Impact on the Global In-Situ hybridization Market
COVID-19 has positively impacted the market. With the help of in situ hybridization technology, scientists are trying to study the coronavirus's biology and its effects on the human body. The governments and private institutions have increased this division's funding for more research and development in this field. The lockdown imposed worldwide has affected the process of research by slowing them due to the unavailability of the workforce. It has created a gap between supply and demand.
Market Size Available
2019 to 2025
2020 to 2025
By Type, Product, Technique, Application, End User and Region
Various Analyses Covered
Global, Regional & Country Level Analysis, Segment-Level Analysis, , PESTLE Analysis, Porter’s Five Forces Analysis, Competitive Landscape, Analyst Overview on Investment Opportunities
North America, Europe, APAC, Latin America, Middle East & Africa
This research report on the Global In Situ Hybridization Market segmented and sub-segmented into the following categories and analyzed market size and forecast for each segment until 2025.
In Situ Hybridization Market – By Technique:
Based on technique, the fluorescent in-situ hybridization (FISH) market segment contributed a significant share to the global market and is likely to grow rapidly with the highest CAGR during the forecast period owing to the factors such as the high resolution of this technique, the increasing adoption of research activities and laboratories for the diagnosis of cancer, chromosomal abnormalities, and infectious diseases among others.
CISH is also expected to grow at a promising rate during the forecast period, mainly due to an increase in cancer cases around the world and the spread of other infectious diseases.
In Situ Hybridization Market – By Application:
Based on application, the cancer diagnosis segment is anticipated to grow rapidly during the forecast period and likely to contribute significant share during the forecast period owing to the catalyzing factors such as the increasing prevalence of cancer, the increased adoption of FISH in the diagnosis of cancer and the growing demand for FISH-based diagnostics.
The neuroscience segment is expected to grow at a prominent CAGR during the forecast period. The main reason for this growth is the increased adaptation of this technology and the increasing number of neuroscience problem cases.
Cytology and infectious Disease segments will also increase in terms of their revenue as this technique becomes more popular and thus cheaper.
In Situ Hybridization Market – By End User:
Based on end-user, in 2019, the molecular diagnostic laboratories segment has contributed the largest share among end-users. It is anticipated to grow at the highest CAGR during the forecast period due to the availability of expertise in molecular diagnostic laboratories for the FISH technique, the increased prevalence of cancer associated with genetic abnormalities, and the increased adoption of FISH in diagnosing cancer and genetic abnormalities.
In Situ Hybridization Market – By Type:
In Situ Hybridization Market – By Product:
The probes and kits had the largest market share in 2019 and are expected to grow with a healthy rate during the forecast period. The growing use of reagents in research and diagnostic devices is a significant factor responsible for giving a high growth rate to this segment. Another major factor contributing to the growth rate is the need for reliable, specific, and rapid detection of cancer and genetic disorders in the early stages.
The instruments segment is expected to register a reasonable growth rate during the forecast period as the adaptation of this technique increases among the medical companies, and there is a rise in the growth of infectious disease and cancer-related problems.
In Situ Hybridization Market – By Region:
The Global In Situ Hybridization Market was dominated by North America, with the largest market share globally and was followed by Europe.
North America led the world in terms of revenue in 2019 and is expected to grow reasonably in the forecast period. The increasing incidence of cancer and infectious diseases in the region is driving the focus on developing personalized medicine and diagnostics tests, thus contributing largely to such growth rates. The strong demand for early cancer detection capabilities has mad ensure that ISH-based markets register steady growths during the forecast period. Research laboratories and academic institutes with modern facilities have helped in this market development and contributed to growth.
Europe had the second largest market share in 2019. The primary factor is the rise in the geriatric population and the development of a quality healthcare system worldwide. The rising government initiatives have further boosted the regional market. The presence of skilled professionals will also help in increasing the regional market revenue and growth factor.
The Asia Pacific is expected to register the highest growth among all other regions during the forecast period. Emerging markets such as India and China offer significant growth opportunities for MDx-based technology (including ISH) owing to the rising geriatric population and the growing prevalence of infectious diseases in these countries. The development of healthcare facilities has also improved this market. Increasing investments by respective government bodies and leading players in these countries ensure that the growth rate and revenue will increase in the future.
NOTABLE COMPANIES IN THE MARKET
Some of the companies playing a crucial role in the Global In Situ Hybridization Market profiled in this report are Abbott Laboratories, Inc. (U.S.), F. Hoffmann-La Roche AG (Switzerland), Leica Biosystems Nussloch GmbH (Germany), Agilent Technologies (U.S.), Thermo Fisher Scientific, Inc. (U.S.), Merck KGaA (Germany), PerkinElmer, Inc. (U.S.), Exiqon A/S (Denmark), BioGenex Laboratories, Inc. (U.S.), Advanced Cell Diagnostics, Inc. (U.S.), and Bio SB Inc. (U.S.).
RECENT MARKET DEVELOPMENTS:
1.1 Market Definition
1.2 Study Deliverables
1.3 Base Currency, Base Year and Forecast Periods
1.4 General Study Assumptions
2. Research Methodology
2.2 Research Phases
2.2.1 Secondary Research
2.2.2 Primary Research
2.2.3 Econometric Modelling
2.2.4 Expert Validation
2.3 Analysis Design
2.4 Study Timeline
3.1 Executive Summary
3.2 Key Inferences
4. Drivers, Restraints, Opportunities, and Challenges Analysis (DROC)
4.1 Market Drivers
4.2 Market Restraints
4.3 Key Challenges
4.4 Current Opportunities in the Market
5. Market Segmentation
5.1.4 Y-o-Y Growth Analysis, By Technique
5.1.5 Market Attractiveness Analysis, By Technique
5.1.6 Market Share Analysis, By Technique
5.2.2 Cancer Diagnosis
5.2.5 Infectious Disease
5.2.6 Y-o-Y Growth Analysis, By Application
5.2.7 Market Attractiveness Analysis, By Application
5.2.8 Market Share Analysis, By Application
5.3 End User
5.3.2 Molecular Diagnostic Laboratories
5.3.3 Academic And Research Institutions
5.3.4 Y-o-Y Growth Analysis, By End User
5.3.5 Market Attractiveness Analysis, By End User
5.3.6 Market Share Analysis, By End User
5.4.4 Y-o-Y Growth Analysis, By Type
5.4.5 Market Attractiveness Analysis, By Type
5.4.6 Market Share Analysis, By Type
5.5.3 Probes & Kits
5.5.4 Y-o-Y Growth Analysis, By Type
5.5.5 Market Attractiveness Analysis, By Type
5.5.6 Market Share Analysis, By Type
6. Geographical Analysis
6.1.1 Regional Trends
6.1.2 Impact Analysis
6.1.3 Y-o-Y Growth Analysis
184.108.40.206 By Geographical Area
220.127.116.11 By Technique
18.104.22.168 By Application
22.214.171.124 By End User
126.96.36.199 By Type
188.8.131.52 By Product
6.1.4 Market Attractiveness Analysis
184.108.40.206 By Geographical Area
220.127.116.11 By Technique
18.104.22.168 By Application
22.214.171.124 By End User
126.96.36.199 By Type
188.8.131.52 By Product
6.1.5 Market Share Analysis
184.108.40.206 By Geographical Area
220.127.116.11 By Technique
18.104.22.168 By Application
22.214.171.124 By End User
126.96.36.199 By Type
188.8.131.52 By Product
6.2 North America
6.1.2 United States
6.3.6 South Korea
6.5 Latin America
6.4.5 Rest of Latin America
6.6 Middle East & Africa
7. Strategic Analysis
7.1 PESTLE analysis
7.2 Porter’s Five analysis
7.2.1 Bargaining Power of Suppliers
7.2.2 Bargaining Power of Consumers
7.2.3 Threat of New Entrants
7.2.4 Threat of Substitute Products and Services
7.2.5 Competitive Rivalry within the Industry
8. Market Leaders' Analysis
8.1 Abbott Laboratories, Inc
8.1.2 Product Analysis
8.1.3 Financial analysis
8.1.4 Recent Developments
8.1.5 SWOT analysis
8.1.6 Analyst View
8.2 F. Hoffmann-La Roche AG
8.3 Leica Biosystems Nussloch GmbH
8.4 Agilent Technologies
8.5 Thermo Fisher Scientific, Inc.
8.6 Merck KGaA
8.7 PerkinElmer, Inc.
9. Competitive Landscape
9.1 Market share analysis
9.2 Merger and Acquisition Analysis
9.3 Agreements, collaborations and Joint Ventures
9.4 New Product Launches
10. Market Outlook and Investment Opportunities
a) List of Tables
b) List of Figures