Microcarrier Market

Global Microcarrier Market Size (2023 to 2028)

The global market size for microcarriers is predicted to be worth USD 3.01 billion by 2028 from USD 2.15 billion in 2023, growing at a CAGR of 6.98% from 2023 to 2028.

Microcarriers are tiny beads made of various materials such as gelatin, dextran, cellulose, plastic, and glass. They help increase the viability of cells by providing anchorage or an attachment surface for the suspended cell culture. They also increase production capacity, improve culture robustness, make process scaling easier, and lower the cost of cell manufacturing. As a result, they're commonly used in cell-line manufacturing and bioreactors. A microcarrier is a support matrix in bioreactors that permits adherent cells to grow. For example, microcarriers are commonly utilized to generate protein-producing or virus-producing adherent cell populations in the large-scale commercial manufacturing of biologics (proteins) and vaccinations. Microcarrier cell culture is often done in spinner flasks, although alternative containers, such as rotating wall microgravity bioreactors or fluidized bed bioreactors, may also support microcarrier-based cultures.

Impact of COVID-19 on the global microcarrier market:

COVID-19 is an infectious disease-causing coronavirus that has only recently been discovered. Following the World Health Organization's (WHO) declaration of the epidemic as a pandemic, a combination of big pharmaceutical corporations and small start-ups rushed to create treatments and vaccinations. Companies have increased their research and development efforts to create vaccinations and treatments to combat the virus. Vaccine-related research in pharmaceutical and biotechnological firms, research centers, and academic and research institutes is critical, and operations and output have been largely unaffected. The availability of financing and the demand for cell culture supplies, particularly microcarrier products, are likely to expand as research scales up. COVID-19 Patients are now being treated symptomatically after vaccinations, and antiviral drugs have been authorized or are in development. The COVID-19 pandemic was a significant factor in increasing vaccine manufacture to fight the virus.

MARKET DRIVERS:

Increased R&D expenditure by pharmaceutical and biotechnology companies and a shift away from stainless-steel bioreactors in favor of single-use bioreactors are driving the market forward. Clinical trials have shown cell-based vaccinations to be as effective, safe, and productive as egg-based vaccines. Microcarriers allow producers to increase the number of cells cultivated in a single tank, allowing for more efficient large-scale production in bioreactors with capacities higher than 1,000 liters. New Microcarriers, such as dissolvable Microcarriers and temperature-sensitive Microcarriers, enable adherent cells to be optimized for production. Factors such as rising demand for cell-based vaccines and therapies, the rapid rise of the biologics and biosimilar markets, and increased R&D and funding for cell therapy research drive the microcarrier market.

The rising prevalence of chronic diseases worldwide is expected to boost the use of microcarriers.

Compared to typical tissue culture plastics, microcarriers have a greater surface area. They serve a crucial function in boosting the cell population, which can aid researchers in developing a variety of treatments. One of the most common uses for microcarriers is the production of vaccinations. Governments worldwide are boosting their spending on various sorts of healthcare research, and corporations are being encouraged to expand their research and development operations to take advantage of new cell therapy technology. Microcarriers are quickly becoming an essential component of 3D cultures, and the growing market for 3D cell culture is a viable application arena for microcarriers.

MARKET RESTRAINTS:

Microcarriers adhered to the cells, which must be collected via a costly down-streaming process. These are the most significant obstacles that the microcarrier market is facing and are impeding its growth of the microcarrier market. In addition, the high cost of cell biology research and the lack of inexpensive serum-free media are other significant challenges anticipated to limit the market's expansion during the forecast period.

REPORT COVERAGE:

This market research report on the global microcarrier market has been segmented and sub-segmented based on product, application, end-user, and region.

Microcarrier Market – By Product:

• Consumables
• Equipment

Based on the product, the consumables segment held the largest share of the global microcarrier market in 2022. The increased use of various microcarrier beads, mediums, and reagents for various culture methods and applications is a key factor driving the consumables segment's rise throughout the forecast period.

Microcarrier Market – By Application:

• Cell therapy
• Vaccine manufacturing
• Biologics manufacturing

Over the forecast period, the cell therapy segment is expected to grow at the fastest rate by application. Microcarriers aid in the development of cost-effective cells by lowering both fixed and variable costs in large-scale manufacturing. The current situation has changed due to technological improvements, and the importance of microcarriers in cell treatment has grown. As a result, these microcarriers are thought to be useful beads for large-scale cell manufacturing or cell treatment.

Microcarrier Market – By End-User:

• Pharmaceutical & Biotechnology Companies
• Contract Research Organizations & Contract Manufacturing Organizations
• Academic and Research Institutes
• Cell Banks

Microcarriers will be increasingly used by academic and research institutes to test and produce a wide range of medicines and vaccines and assist patients in combating terminal diseases. Researchers sometimes want a larger surface area and a larger cell population to conduct a more profound analysis while creating cell treatments. Microcarriers are frequently utilized in this situation because they have a more significant surface area and can assist in enlarging the cell population.

Microcarrier Market – By Region:

• North America
• Europe
• Asia-Pacific
• Latin America
• Middle East and Africa

Geographically, most of the global microcarrier market was controlled by the North American region in 2022. This is mainly due to the region's growing gene therapy and cell therapy research and the organizations that support it. The American Society of Gene and Cell Therapy, for example, is responsible for supporting research and is also pressuring biopharmaceutical and biotech corporations to improve their R&D. In addition, the biologics industry in the United States is experiencing solid and quick expansion, which is one of the primary drivers accelerating the microcarrier market in this region.

Because of technological advancements in company R&D, Europe ranked second in the global market, resulting in increased acceptance of microcarrier products.

The Asia Pacific market is expected to grow at the fastest CAGR during the forecast period due to pharmaceutical companies' geographical expansion in emerging countries, collaborations, and partnerships between government organizations and biopharmaceutical manufacturers.

KEY MARKET PARTICIPANTS:

Thermo Fisher Scientific, Danaher, Corning Incorporated, Merck KGaA, GE Healthcare, Becton, Dickinson and Company, Lonza, Eppendorf AG, and Sartorius AG are a few of the prominent companies operating in the global microcarrier market profiled in this report.

RECENT HAPPENINGS IN THIS MARKET:

• The Australian Government announced to invest of USD 25 million in Australian-led stem cell research in 2021 to help discover and develop new, safe, and effective cures for catastrophic diseases and injuries.
• Clover Biopharmaceuticals chose GE's FlexFactory biomanufacturing platform for their new Chinese manufacturing site in 2018.