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Global Protein Sequencing Market Size, Share, Trends, COVDI-19 Impact & Growth Analysis Report – Segmented By Product and Service, Application, End-User & Region (North America, Europe, APAC, Latin America, Middle East and Africa), Industry Forecast (2023 to 2028)

Published: March, 2023
ID: 12876
Pages: 190
Formats: report pdf report excel report power bi report ppt

Global Protein Sequencing Market Size (2023 to 2028)

The global protein sequencing market is estimated to be growing at a CAGR of 5.77% from 2023 to 2028 and be worth USD 1434 million by 2028 from USD 1083 million in 2023.

Protein sequencing is a sequencing technology that uses the mass spectrum to determine and analyze the amino acid sequence. Researchers can use this method to learn more about protein structure. Protein sequencing has become a popular high-throughput proteomic technology with various applications, and protein sequencing is done using various computational and experimental methods, including Edman degradation and mass spectrometry. Several biotechnology and pharmaceutical businesses are investing heavily in protein sequencing as a tool for medication development. Furthermore, advances in high-throughput technology have enabled rapid and parallel protein sequencing. Even modest amounts of protein can be sequenced at high resolution to aid in the characterization of gene products and subcellular structures.

Impact of COVID-19 on the global protein sequencing market:

COVID-19 is a highly infectious virus that spreads through human contact. SARS-CoV-2 and HCoV-19 are the pathogens that cause COVID-19, a novel type of pneumonia that began in Wuhan, China, and has since spread to almost every country. COVID-19 was declared a global pandemic by the World Health Organization (WHO) on March 11, 2020, due to rapid transmission across country borders and many confirmed cases. As this virus's surface protein changes due to mutation, increasing research activity in protein sequencing has become necessary. As a result, the protein sequencing market dropped in demand during the lockdown. Still, as a result of the circumstances and increased awareness among researchers about the relevance of protein sequencing studies, the market reached new heights.


The increased focus of biotechnology and pharmaceutical companies on target-based medication development operations in various developing and developed areas is one of the factors propelling the global protein sequencing market growth.

Technological developments in mass spectrometers are a good example. Individual peptide residues may now be detected due to improvements in nanopore sensors and single-molecule fluorescent devices. In addition, the market is being supported by increased funding for proteomics research in several emerging and developed countries. An increase in demand for protein biomarkers in the drug development process is one of the significant factors accelerating the market’s growth rate.

Protein sequencing is gathering steam as a tool for detecting new peptides in human antibodies, and antigens are becoming more widely used. Nonetheless, technological developments in identifying isobaric residues in protein sequences are projected to open up a large number of new opportunities in the global protein sequencing market. Furthermore, developments in clinical mass spectrometry and analytical methodologies are expected to drive the protein sequencing market growth over the forecast period. In addition, new business opportunities have arisen due to recent advancements in de novo peptide sequencing and analytical technologies and the usage of neural networks.


High infrastructure costs would constrain the market's expansion during the forecast period. In addition, over the forecast period, factors such as the preparation of pure protein samples and the requirement for qualified researchers and laboratory personnel will challenge the global protein sequencing market's expansion.




Market Size Available

2023 to 2028

Base Year


Forecast Period

2023 to 2028

Segments Covered

By Product and Service, Application, End-User & Region

Various Analyses Covered

Global, Regional & Country Level Analysis, Segment-Level Analysis, DROC, PESTLE Analysis, Porter’s Five Forces Analysis, Competitive Landscape, Analyst Overview of Investment Opportunities

Regions Covered

North America, Europe, APAC, Latin America, Middle East & Africa


This report on the global protein sequencing market has been segmented and sub-segmented into products & services, applications, end-user, and region.

Global Protein Sequencing Market Analysis – By Product & Service:

  • Sample Preparation Products & Services
  • Protein Sequencing Products
  • Reagents & Consumables
  • Instruments
  • Analysis Products/Software
  • Protein Sequencing Services

The launch of technologically advanced instruments, software, and services for protein sequencing, the high cost of sequencing infrastructure, the complexities associated with protein sequencing procedures, and the availability of advanced sequencing infrastructure among service providers are all factors driving growth in the protein sequencing services segment.

Global Protein Sequencing Market Analysis – By Application:

  • Biomarker Discovery
  • Protein Engineering Studies
  • Biotherapeutics

Protein Engineering Studies is predicted to be the fastest-growing segment in terms of application. Protein engineering is manipulating protein structures to achieve desired qualities or the creation of proteins with specific architectures. Bioformulations such as antibodies, nucleic acid products, and vaccines make up the bulk of therapeutic medications on the market today. The incorporation of unnatural amino acids is a field in protein engineering that the firms concentrate on for site-specific conjugation of functional moieties to biopharmaceuticals.

Global Protein Sequencing Market Analysis – By End-User:

  • Academic Institutes & Research Centers
  • Pharmaceutical & Biotechnology Companies

Based on the end-user, the academic institutes & research centers segment led the global protein sequencing market in 2021 due to governmental and private institutes' increased funding for proteome research. Protein sequencing is used in proteomic research at academic institutes and research centers. However, these institutes rely on protein sequencing suppliers to conduct proteomic research due to a lack of infrastructure, a limited number of samples, and budget limits to buy protein sequencing consumables. Protein sequencing services, such as mass spectrometry and Edman degradation, are also available through numerous academic institutes and research organizations.

Global Protein Sequencing Market Analysis – By Region:

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East and Africa

Because of increased technological advancements and a more robust healthcare infrastructure, North America is likely to be the most significant protein sequencing market. The pharmaceutical sector in the United States is one of the most research-intensive industries. And the pharmaceutical business is heavily committed to implementing advanced solutions to improve pipeline development and patient care. Furthermore, there is a growing emphasis on target-based medication development, with protein sequencing studies assisting in creating target-based drugs. Additionally, both government and non-government entities are funding research in proteomics.

Europe has the world's second-largest market share. The expansion of the protein sequencing market in Europe is likely to be fueled by an increase in demand for protein sequencing and increased awareness.

During the forecast period, the protein sequencing market in the Asia Pacific is expected to account for a large share of the protein sequencing market in terms of value. During the projection period, China is expected to have the quickest growth rate. In addition, increasing government initiatives and investments in life science research and development in countries like Japan and India will likely boost the growth of the protein sequencing market over the forecast period.


Companies playing a vital role in the global protein sequencing market profiled in this report are Thermo Fisher Scientific, Inc., Shimadzu Corporation, Agilent Technologies, SGS S.A., Rapid Novor, Charles River Laboratories, Bioinformatics Solutions, Proteome Factory, Selvita, and Waters Corporation.


  • Shimadzu expanded its mass spectrometry platform in 2018 by introducing a new Q-TOF instrument.
  • NIST introduced TMAP in 2019 to allow NIST scientists and engineers to bring their lab-created ideas to market quickly. TMAP (Technology Maturation Accelerator Program) is a platform that aims to help numerous technologies get over the "valley of death" that occurs between the prototype and implementation stages.

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What are the key drivers of growth in the protein sequencing market?

The key drivers of growth in the protein sequencing market include the increasing demand for personalized medicine, rising prevalence of chronic diseases, technological advancements in protein sequencing techniques, and growing government funding for proteomics research.


What are the main challenges faced by the protein sequencing market?

The main challenges faced by the protein sequencing market include high cost of equipment and services, lack of skilled professionals, and the need for sophisticated data analysis software.


What are the latest technological advancements in the protein sequencing market?

The latest technological advancements in the protein sequencing market include high-throughput mass spectrometry, advanced software for data analysis, and new techniques for post-translational modification analysis.


Which geographical regions are expected to see the highest growth in the protein sequencing market?

North America is expected to see the highest growth in the protein sequencing market, owing to the presence of well-established healthcare infrastructure and high demand for personalized medicine.


What are some of the key players operating in the protein sequencing market?

Some of the key players operating in the protein sequencing market include Thermo Fisher Scientific, Danaher Corporation, Bio-Rad Laboratories, Waters Corporation, and GenScript Biotech Corporation.


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