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Global Protein A Resins Market Size, Share, Trends, COVID-19 Impact & Growth Analysis Report – Segmented By Product Type (Natural Protein A Resin, Recombinant Protein A Resin), Application, End Users, Matrix Type & Region - Industry Forecast (2022 to 2027)

Published: January, 2022
ID: 337
Pages: 175
Formats: report pdf report excel report power bi report ppt

Protein A Resins Market Size (2022 to 2027)

The size of the global protein a resins market is expected to be worth USD 729.1 million by 2027 from USD 492.6 million in 2022, growing at a CAGR of 8.2% from 2022 to 2027. The market is showcasing the evident potential in the mentioned forecasting period.

The growing demand for the best treatment of chronic diseases to get better results that are cost-effective and widely accepted. Protein A resins are commonly used in chromatography as well.


Increasing research on monoclonal antibodies and the growing usage of chromatography in drug discovery and protein engineering has given rise to a wide range of protein-based drugs that accelerate the global protein A resins market.

The global protein A resins market is expected to grow at a steady growth rate during the forecast period, owing to increasing applications of monoclonal antibody diagnostics and therapies to manage chronic diseases such as cancer, rheumatoid arthritis, and others. Furthermore, increasing research interest in synthetic biology to the adoption of protein products to make protein-infused drugs and formulations, collaboration and acquisitions of major market players, and growing technological developments are anticipated to favor the growth of the protein A resins market. In addition, growing demand for pre-packaged disposable columns, increased demand for therapeutic antibodies, and increased pharmaceutical R&D spending are supporting the market's growth rate. In Europe, key pharmaceutical and biopharmaceutical research centers have been established over the past several years. Additionally, regulatory agencies' increased approvals of monoclonal antibody products to meet the growing demand for immunotherapy are estimated to further fuel the protein A resins market growth.

Many significant advances have been observed in monoclonal antibodies used to treat many chronic and infectious diseases. Protein A resins are widely used to purify monoclonal antibodies, a critical factor that improves growth prospects for the next forecast period. In addition, massive clinical trials in synthetic biologics and monoclonal antibodies are expected to accelerate the rise of the global A resins market.


However, the high costs associated with these high-end products may restrain the market's growth during the forecast period. Additionally, the availability of alternatives such as crystallization, ultrafiltration, and others as purification methods could slow the development of the market during the forecast period.




Market Size Available

2021 to 2027

Base Year


Forecast Period

2022 to 2027

Segments Covered

By Product Type, Application, End-User, Matrix Type, and Region

Various Analyses Covered

Global, Regional & Country Level Analysis, Segment-Level Analysis; DROC, PESTLE Analysis; Porter's Five Forces Analysis, Competitive Landscape, Analyst Overview of Investment Opportunities

Regions Covered

North America, Europe, APAC, Latin America, Middle East & Africa

Market Leaders Profiled

GE Healthcare, Repligen Corporation, Novasep, Tosoh Bioscience, GenScript, Thermo Fisher Scientific, EMD Millipore, and Expedeon Ltd.


This research report on the global protein a resins market has been segmented & sub-segmented based on the product type, application, end-user, matrix type, and region.

Protein A Resins Market - By Product Type:

  • Natural
  • Recombinant

Based on product type, the recombinant protein A resins segment is anticipated to account for the largest share of the market during the forecast period. Recombinant protein A is produced in E. coli and functions the same way as normal protein A resins. The recombinant protein type is favored where another production origin provides less non-specific binding.

Protein A Resins Market - By Application:

  • Immunoprecipitation
  • Antibody Purification

Based on the application, the segment of immunoprecipitation is expected to show the highest CAGR during the forecast period. In the research and development sector, immunoprecipitation is widely applicable. As protein A resins are used in immunoprecipitation techniques, their demand will go hand in hand with the increasing demand for immunoprecipitation. In addition, the growing demand for therapeutic antibodies and high antibody research and development activities will also contribute to improving the segment's growth to some extent.

Protein A Resins Market - By Matrix Type:

  • Glass or Silica
  • Agarose
  • Organic Polymer

Based on the matrix type, the glass or silica-based matrix segment is expected to show significant growth over the forecast period owing to improved longevity, mechanical strength, and ability to integrate high metal dopant absorption.

Protein A Resins Market - By End User:

  • Biopharmaceutical Manufacturers
  • Clinical Research Laboratories
  • Academic Institutes

Based on the end-user, the biopharmaceutical manufacturers segment is anticipated to lead the market during the forecast period. Biopharmaceutical companies extensively use protein A resins to purify monoclonal antibodies with great alarm. Therefore, the biopharmaceutical industry's development of therapeutic monoclonal antibodies is expected to rise to meet its growing demand. As monoclonal antibodies' production increases, the need for protein A resins for large-need purification will increase. In addition, the ever-increasing trend of outsourcing large-scale production to contract research organizations would also increase the clinical research laboratories' end-user segment in the market.

Protein A Resins Market - By Region:

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East and Africa

The North American region was the largest market for Protein A resin, accounting for approximately 37% in 2020 due to many investments in the development of monoclonal antibodies, followed by Europe. The European protein A resin market was dominated by the German protein A resin market in 2020 and is expected to show a positive trend throughout the projection period. Most sales would be due to drug discovery and development and the growing demand for immunotherapy drugs to treat chronic diseases. As a result, the uptake of protein A resins products is increasing at a reasonable rate. In addition, increased investment in protein research is attracting market players to establish their businesses in Germany.

The UK Protein A resins market is expected to grow at over 7.4% CAGR during the forecast period. However, the increase in the adoption by various industries and the presence of the major market players in the country will influence the market's growth in the future. In addition, the region has a high demand for recombinant proteins, immunoglobulins, and protein antigen complexes, leading to an expansion of immunotherapy applications in the UK.

Other European countries such as Sweden, Switzerland, Netherlands, and France are expected to have a healthy market rate during the projected period. The presence of the major market players in these countries has significantly impacted the European protein A resins market growth. In addition, the increasing rate of chronic diseases such as rheumatoid arthritis will generate significant market growth. For example, in Sweden, the overall nationwide incidence of rheumatoid arthritis was around 42 per 100,000, with a high rate of incidences occurring in the age group of 70–79 years for both women and men.

Asia Pacific region is estimated to be the fastest-growing region with a healthy compound annual growth rate due to many untapped markets and growing awareness about the developments in the market.


Companies leading the global protein A resins market profiled in the report are GE Healthcare, Repligen Corporation, Novasep, Tosoh Bioscience, GenScript, Thermo Fisher Scientific, EMD Millipore, and Expedeon Ltd. Major Players in the market enter into strategic agreements to develop raw materials required to manufacture Protein A resins.

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What was the size of the protein a resins market worldwide in 2021?

The global protein a resins market size was valued at USD 455.3 million in 2021.

Which segment by product type accounted for the major share in the protein a resins market?

Based on the product, the recombinant segment accounted for the leading share of the market in 2021.

Which region was the leading in the global protein a resins market in 2021?

Geographically, the North American region accounted for the major share in the global protein a resins market in 2021.

What are some of the promising companies in the protein a resins market?

GE Healthcare, Repligen Corporation, Novasep, Tosoh Bioscience, GenScript, Thermo Fisher Scientific, EMD Millipore, and Expedeon Ltd are a few of the notable companies in the protein a resins market.

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